Bugs and Drugs

Question 1

Gram + cocci (streptococcus)

Answer 1

1st line:
- Penicillin
- Ampicillin
- Amoxicillin

Alternatives:
- Semi-pen
- cefazolin
- macrolides
- quinolones
- vancomycin
- BL/BLI
- ceftriaxone
- clindamycin
- TMP/SMX
- carbapenem

Question 2

MSSA

Answer 2

1st line:
- cefazolin
- semi-pen

Alternatives:
- Macrolides
- clindamycin
- quinolones
- vanco
- BL/BLI
- ceftriaxone
- TMP/SMX
- rifampin
- carbapenem
- linezolid
- daptomycin

Question 3

MRSA

Answer 3

1st line:
- vancomycin

Alternatives:
- linezolid
- daptomycin
- tigecycline

Question 4

Enterococcus

Answer 4

1st line:
- ampicillin + gentamycin

Alternatives:
- vancomycin + gentamycin
- linezolid
- carbapenem
- daptomycin
- tigecycline

Question 5

Gram negative bacilli (E.coli, Enterobacter, H. Influenzae)

Answer 5

1st line:
- ceftriaxone

Alternatives:
- gentamicin
- BL/BLI
- quinolones
- TMP/SMX
- ampicillin

Question 6

P. Aeruginosa

Answer 6

1st line:
- pip/taz + tobramycin or cipromycin
- cefepime + tobramycin or cipromycin

Alternatives:
- carbapenem + tobramycin or cipromycin

Question 7

Anaerobic gram negative bacilli

Answer 7

1st line:
- clindamycin
- metronidazole
- BL/BLI

Alternatives:
- carbapenem