bug to drug Flashcards

1
Q

MRSA

A

some 3rd gen cephalosporins (CTX
some 4th gen cephalosporins (cefepime)

TMP/SMX

macrolides (azithro, clarithro, erythro)

vancomycin

linezolid

clindamycin

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2
Q

CoNS

A

3rd gen cephalosporins (CTX)

4th gen cephalosporins (cefepirne)

vancomycin

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3
Q

resistant strep pneumoniae

A

3rd gen cephalosporins (CTX)

4th gen cephalosporins (cefepirne)

vancomycin

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4
Q

VRE

A

3rd gen cephalosporins (CTX)

4th gen cephalosporins (cefepirne)

daptomycin but not as good for e. faeclum?

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5
Q

staph aureus (MSSA)

A
penicillin
nafcillin
piperacillin, ticarcillin
above + BLI
carbapenems

ist generation cephalospoirns (cefaz/keflex)

3rd generation cephalosporins (CTX)

4th generation cephalosporins (cefepime)

ciprofloxacin
levofloxacin and moxifloxacin work, but work better for staph

aminoglycosides (gent, tobra, erythro)

TMP/SMX (staph more than strep)

vancomycin

linezolid

daptomyin

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6
Q

strep pneumo (not resistant)

A
PCN
ampicillin
amoxicillin
above + BLI
piperacillin, ticarcilin
above + BLI
carbapenems

some 2nd gen cephalosporins (cefurox)

3rd gen cephalosporins (CTX)

4th gen cephalosporins (cefepime)

ciprofloxacin, levofloxacin, moxifloxacin

aminoglycosides (gent, tobra, amik)

TMP/SMX (staph more than strep)

vancomycin

linezolid

daptomyin

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7
Q

e. coli
strep A-G
viridans streptococci

A

Penicillin
piperacillin, ticarcillin
+ BLI
carbapenems

3rd gen cephalosporins (CTX)

4th gen cephalosporins (cefepime)

sometiems ciprofloxacin

aminoglycosides (gent, tobra, amik)
macrolides (azithro, clarithro, erythro)

bancomycin

linezolid

daptomycin

lincomycin

clindamycin

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8
Q

oral anaerobes

A

clindamycin

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9
Q

GPR bacteria

A

b. cereus
b. anthracis
listeria
c. perfringens
c. diff
corynebacteria
nocardia

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10
Q

GPR drugs (that work on all)

A

ampicillin, amoxicillin
carbapenems

levofloxacin, moxifloxacin

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11
Q

c. perfringens

A

PCN

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12
Q

listeria

A

ampicillin or amoxicillin (or PCN?) plus BLI

aminoglycosides (gent, tobra, amik) synergy

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13
Q

nocardia

A

3rd gen cephalosporins (CTX)

TMP/SMX

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14
Q

anthrax

A

ciprofloxacin

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15
Q

c. diff

A

metronidazole

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16
Q

GNC bugs

A

n. meningitids
n. gonorrhea
moraxella

17
Q

GNC drugs

A

carbapenems
other beta lactams sometimes except nafcillin, diclox (never works)

3rd gen cephalosporins (CTX) sometimes ceftaz

sometimes 2nd gen cephalospoirns (cefurox)

4th gen cephalosporins (cefepime)

monobactam (aztreonam)

all quniolones (ceprofloxacin, levofloxacin, moxifloxacin)

sometimes macrolides (azithromycin, clarithromycin, erythromycin)

18
Q

non-resistant GNR bugs

A
e coli
h. flu
salmonella
shigella
campylobacter
francisella
yersinia
b. fragilis
prevotella (anaerobes)
legionella
mycoplasma
chlamydia
19
Q

GNRs (all) drugs

A

piperacillin, ticarcillin
carbapenems

3rd gen cephalosporins (CTX) (Ceftaz)
4th gen cephalosporins (cefepime)

aztreonam

ciprofloxacin

gentomycin, tobra, amik (aminoglycosides)

sometimes TMP/SMX

20
Q

GNR anaerobes

A

best drug metronidazole!

beta lactams with BLIs
carbapenems

cefotetan (2nd gen cephalo)

moxifloxacin

50% clindamycin

21
Q

E. coli

A

some ampicillin amoxicillin
add bli for better coverage

keflex/cefaz some (1st ten cephalosporin)
cefurox some (2nd gen)

TMP/SMX some

22
Q

H. flu

A

cefuroxime (2nd gen cephalosporin)

macrolides (azithro, clarithro, erythro)

23
Q

legionella

A

levofloxacin
moxifloxacin

macrolides (azithro, clarithro, erythro)

24
Q

atypical GNRs

A

moxifloxacin

macrolides (azithro, clarithro, erythro)

25
Q

resistant GNRs (bugs)

A
serratia
pseudomonas
acinetobacter
citrobacter
enterobacter
klebsiella
26
Q

drugs for resistant GNRs

A

piperacillin, ticarcillin with BLI
carbapenems

3rd gen cephalosporins (ceftaz)

4th gen cephalosporins (cefepime)

sometimes aztreonam

sometimes quinolines (ciprofloxacin, levofloxacin, moxifloxacin)

sometimes aminoglycodises (gentamycin, tobramycin, amik)

27
Q

stentrophomonas

A

TMP/SMX