buffer and henderson-hasselbalch equation Flashcards

1
Q

Most brands of antifreeze contain

A

ethylene glycol
✔sweet taste
✔initial effect drunkenness

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2
Q

ethylene glycol is metabolized in the liver to

A

glycolic acid

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3
Q

Why Is Glycolic Acid Toxic?

A

overwhelms the buffering ability of the HCO3− in the blood, causing the blood pH to drop

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4
Q

acidosis

A

When the blood pH is low, its ability to carry O2 is compromised

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5
Q

treatment for acidosis

A

give the patient ethyl alcohol, which has a higher affinity for the enzyme that catalyzes the metabolism of ethylene glycol

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6
Q

solutions that resist changes in pH
when an acid or base is added

A

buffers

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7
Q

how do buffers act

A

neutralizing acid or base that is
added to the buffered solution

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8
Q

Many buffers are made by mixing a solution of a ___ with a solution of ___ containing its ___

A

weak acid, soluble salt, conjugate base anion

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9
Q

added acid reacts with the __ to make more __
added base reacts with the __ to make more __

A

A-, HA

HA, A-

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10
Q

Buffers can also be made by mixing a ___, (B:), with a ___ of its ___

A

weak base, soluble salt, conjugate acid

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11
Q

amount of acid or base a buffer can neutralize

A

buffering capacity

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12
Q

pH range the buffer can be effective

A

buffering range

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13
Q

The effectiveness of a buffer depends on two factors

A

(1) the relative amounts of acid and base, and (2) the absolute concentrations of acid and base

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14
Q

A buffer will be most effective when the

A

+largest mol

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