buffer and henderson-hasselbalch equation Flashcards
Most brands of antifreeze contain
ethylene glycol
✔sweet taste
✔initial effect drunkenness
ethylene glycol is metabolized in the liver to
glycolic acid
Why Is Glycolic Acid Toxic?
overwhelms the buffering ability of the HCO3− in the blood, causing the blood pH to drop
acidosis
When the blood pH is low, its ability to carry O2 is compromised
treatment for acidosis
give the patient ethyl alcohol, which has a higher affinity for the enzyme that catalyzes the metabolism of ethylene glycol
solutions that resist changes in pH
when an acid or base is added
buffers
how do buffers act
neutralizing acid or base that is
added to the buffered solution
Many buffers are made by mixing a solution of a ___ with a solution of ___ containing its ___
weak acid, soluble salt, conjugate base anion
added acid reacts with the __ to make more __
added base reacts with the __ to make more __
A-, HA
HA, A-
Buffers can also be made by mixing a ___, (B:), with a ___ of its ___
weak base, soluble salt, conjugate acid
amount of acid or base a buffer can neutralize
buffering capacity
pH range the buffer can be effective
buffering range
The effectiveness of a buffer depends on two factors
(1) the relative amounts of acid and base, and (2) the absolute concentrations of acid and base
A buffer will be most effective when the
+largest mol