brugada syndrome

Question 1

what is brugada syndrome

Answer 1

inheritable condition

pts have idiopathic ventricular fibrillation and no evidence of causative structural cardiac disease

Question 2

how many genes can be associated with brugada syndrome

Answer 2

12

Question 3

is brugada syndrome more common in men or women

Answer 3

8x more likely in men

Question 4

is brugada syndrome autosomal dominant or recessive

Answer 4

autosomal dominant

Question 5

what are the VF triggers in brugada syndrome

Answer 5

usually rest or sleep

fever
excessive alcohol, large meals
drug triggers include beta blockers, psychotropics, analgesics and anaesthetics

Question 6

what is the clinical presentation of brugada syndrome

Answer 6

AF is common
risk of polymorphic VT and VF

Question 7

what are the investigations used in brugada syndrome

Answer 7

ECG

Question 8

what are the ECG findings in brugada syndrome

Answer 8

ST elevation and right bundle branch block in V1-V3

findings may be intermittent and change over time

Question 9

what is the diagnostic test for brugada syndrome

Answer 9

provocation ECG testing

Question 10

outline the management of brugada syndrome

Answer 10

ICD
avoid triggers
genetic testing and extend this to family