brucella

Question 1

where does brucella come from ?

Answer 1

cows
sheep
cattle
pigs

Question 2

what are the transmission modes off brucella ?

Answer 2

1- orally - ingestion of unpasteurized milk
2- inhalation
3- skin direct contact
4- conjunctiva

Question 3

what is the incubation period of brucella ?

Answer 3

1-3 weeks

Question 4

what is the presentation of brucellosis ?

Answer 4

fever
rigors
hepatosplenomegaly
low backache
hepatosplenomegaly
lymphadenopathy
spondylitis
endocarditis

Question 5

what is the prognosis of brucellosis ?

Answer 5

full recovery

Question 6

what is the most sensitive test used for the diagnosis of brucellosis ?

Answer 6

ELISA

Question 7

what is the treatment for adults and non localised disease ?

Answer 7

doxycycline plus gentamicin

or
doxycycline plus rifampcin

Question 8

what is the treatment of bone disease in brucellosis ?

Answer 8

doxycycline
plus rifampcin plus gentamicin

or
ciprofloxacin and rifampcin

Question 9

what is the treatment for neurobrucellosis ?

Answer 9

doxycycline plus rifampcin plus ceftriaxone

Question 10

what is the treatment for endocarditis ?

Answer 10

almost always needs surgical intervention
plus
doxycycline
rifampicin
co-trimoxazole
gentamicin

Question 11

what is the treatment of brucellosis in pregnancy ?

Answer 11

rifampcin
co trimoxazole

Question 12

what test can be used for the diagnosis of brucella and what is the gold standard ?

Answer 12

tube agglutination test
gold standard is bone marrow biopsy