Bronchoscopy and EBUS Flashcards
Which patients most commonly have EGFR mutations?
female non smoking asians
What are the most common sites for extrathoracic metastases of lung cancer?
brain
liver
adrenals
bone
What type of lesions is flexible bronchoscopy used to sample?
central lesions
What type of lesions is radial EBUS used to sample?
peripheral lesions
What type of lesions is linear EBUS used to sample?
peribronchial/peritracheal/mediastinal
What determines the M component of the TNM staging?
malignant pleural/pericardial effusions, contralateral tumour nodules or extrathoracic tumour metastases
How is stage I and II NSCLC treated?
surgical resection or stereotactic ablative radiotherapy with curative intent -> adjuvant chemo/radiotherapy in selected cases
How is stage III NSCLC (LN metastases) treated?
wide range of options including chemo/radiotherapy and sometimes surgery in selected cases
How is stage IV NSCLC treated?
chemotherapy, targeted molecular agent, immunotherapy
What is the treatment for SCLC?
chemotherapy +/- prophylactic cranial irradiation
What is the risk of death in bronchoscopy?
1 in 2500
Which malignancy is the leading cause of cancer death?
lung cancer
What is the commonest histopathological subtype of lung cancer?
adenocarcinoma
What is the most common type of mutation in non small cell lung cancer?
KRAS
