broncholitis/RSV Flashcards

1
Q

what is bronchiolitis?

A

inflammation of the fine bronchioles and small bronchi

  • lower resp tract infection
  • usually due to viruses (particularly respiratory syncytial virus (RSV))
  • under 2 years old, peak at 6 months
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2
Q

RSV?

A

most frequent cause of hospitalization in children less than 2 years of age

  • higher rates in indigenous populations in Northern Canada
  • 1% mortality rate, 3% in underlying conditions
  • RSV to asthma link
  • can live on surfaces for several hours, hands for 30 minutes
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3
Q

increased risk of RSV

A
  • if born in november, december, january
  • siblings in day care
  • more than 6 individuals
  • low birth weight
  • male
  • formula fed (immune system isnt as good)
  • eczema family history
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4
Q

initial manifestations of RSV

A
  • rhinorrhea
  • pharyngitis
  • coughing
  • wheezing
  • ear/eye drainage
  • intermittent fever
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5
Q

with progression the symptoms of RSV…

A
  • increased coughing and wheezing
  • tachypnea and retractions
  • cyanosis
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6
Q

severe RSV?

A
  • tachypnea (over 70 breaths/min)
  • listlessness
  • apnea
  • poor air exchange
  • decreased breath sounds
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7
Q

assessment for RSV?

A
  • color
  • movements (headbob)
  • work of breathing
  • auscultation (stridor, wheezing)
  • secretions
  • circulation and hydration
  • caregivers
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8
Q

work of breathing findings?

A
  • resp rate
  • nasal flare
  • tracheal tug
  • in drawing, retractions
  • seesaw breathing
  • sounds: grunting
  • coughing
  • crying
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9
Q

circulation and hydration findings?

A
  • mucous membranes (color, moisture)
  • peripheral and central color mottling normal
  • Ins and outs (IV hydration if nothing by mouth)
  • weight: not only for intake and output, medications are weight based!!
  • nutritional status: at a nutritional risk, if baby cannot coordinate movement for sucking at risk
  • assess sucking reflex!
  • RR greater than 55??/
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10
Q

diagnostics for RSV?

A
o Nasopharyngeal swab- RSV antigen 
	o Chest x-ray: hyperinflation 
	o Arterial blood gases 
	o CBC, electrolytes 
Any other associated infections?
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11
Q

therapeutic management of RSV?

A
  • treat symptoms
  • cool humidified oxygen
  • adequate fluids
  • airway maintenance
  • antipyretics (whether to treat or not??see how child is doing, may be a physiologic response, only treat if over 38.5…)
  • home vs hospital (only children with resp distress and who are at risk (have other comorbidities) stay
  • tachypnea
  • supplemental humidified oxygen
  • brochodilator (assess for response, not every child will be ordered them, only stay on if helpful)
  • epinephrine nebs (hypertonic nebs, stimulate alpha and beta 2 receptors, relaxes smooth muscles of bronchial tree, relieving bronchial spasm)
  • 3% NS nebs (improves mucociliary clearance- like a mucolytic)
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12
Q

nursing diagnosis for RSV (common…)

A
  • ineffective breathing pattern
  • potential fluid volume deficit
  • potential fluid and electrolyte imbalance
  • potential alteration in nutritional status
  • potential discomfort
  • potential anxiety
  • potential knowledge deficit
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13
Q

nursing interventions for RSV?

A
  • VS routine and PRN
  • oxygen above 96%
  • blow by (nasal prologns too big)
  • NS drops prn
  • cardiac sling
  • sat probe change q4h (burns)
  • stirct ins and outs
  • daily weight
  • NPO if RR over 55 bpm
  • hydrate the mother if BF, small frequent feeds
  • group care (everyone assessing the child)
  • tylenol
  • droplet precautions
  • grouping with other RSV positive patients
  • nursing assignment to limit contact with non-RSV patients
  • encourage breastfeeding
  • management of secretions
  • provide meds (small masks, syringe meds)
  • oral and IV hydration
  • frequent monitoring
  • health promotion opportunities
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14
Q

goal of pharmacology care?

A

prevent and control symptoms

  • reduce freq and severity of exacerbations, improve health status, improve exercise tolerance
  • nursing considerations: pre/post resp assess, pt teaching, life span considerations
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15
Q

drugs by inhalation: MDI

A

metered-dose inhaler

  • pressured devices
  • 1 minute in between
  • teaching is important
  • spacers
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16
Q

drugs by inhalation: respimats

A
  • fine mist

- less drug in mouth and oropharynx

17
Q

dry-powder inhalers (DPI)

A

micronized powder
breath activated
spacers not used

18
Q

nebulizers?

A

mist

for some this may be more effective

19
Q

with spacer….

A

57% inhaler device, 22% mouth and throat, 21% lungs

20
Q

without spacer…

A

10% inhaler device, 81% mouth and throat, 9% lungs

21
Q

short-acting beta 2 agonists?

A

bronchial smooth muscle relaxation causing bronchodilation through activating beta2-adrenergic receptors

  • indication: prevention or relief of bronchospasm in asthma or COPD, used PRN inhaled
  • side effects: may see nausea in larger doses, anxiety, palpitations, tremors, increased heart rate—> tachydysrhythmias
    contraindication: BETA BLOCkers!! or taking MAOIs/other sympathomimetics r/t risk of hypertension
  • SALBUTAMOL
22
Q

long-acting beta 2 agonists?

A

bronchial smooth muscle relaxation causing bronchodilation
-prevention/long term control of bronchospasm in asthma or COPD
-fixed schedule (not PRN, must be given with a glucocorticoid in asthma. inhaled)
may increase risk of death if used MONOTHERAPY
-effect may be diminished if taking beta blockers, avoid taking MAOIs other sympathomimetics r/t hypertension

23
Q

anticholinergics?

A

blocks muscarinic receptors in the bronchi—> reduced bronchoconstriction
-indication: slower onset compared to beta agonists. used for prevention of bronchospasm. COPD “off label” for asthma
-inhaled, 1 min gap between inhalers
-SE: dry mouth, throat, nasal congestion, not readily absorbed systemic but if it does can increase intraocular pressure
-contraindications: pt with acute angle glaucoma or prostate enlargement. possible additive toxicity in use with other anticholinergic drugs
EXAMPLE: IPRATOPIUM

24
Q

methylxanthines?

A

mech: bronchodilation by relaxing smooth muscle of the bronchi
-not firmly established, likely from blocking adenosine receptors
-indication: chronic, stable, asthma. decrease frequency and severity of attacks. no longer recommended in COPD. oral or IV
side effects: toxicity!! nausea, vomiting, diarrhea, insomnia, restlessness
contraindications: caffeine, tobacco, marijuana, many drug interactions
example: AMINOPHYLLINE, THEOPHYLLINE

25
Q

bronchodilators life span considerations (children)

A

special delivery devices
SABA approved over 2, may be used younger
methyxanthines: all ages
anticholinergics safety not ensured under 11!!

26
Q

pregnant and older adults bronchodilators

A

weigh benefits vs. risks

27
Q

inhaled coritcosteroids???

A

reduces inflammation, decreases edema and results in bronchodilation. increases responsiveness to beta agonists (ex. salbutamol)
indications: persistent asthma, often used in conjunction with beta agonists. may also be used in COPD
side effects? no adrenal suppression so no serious toxicity
-oral pharyngeal candidiasis, dysphonia
-delay growth in children?
-long term bone loss
not many contraindications when inhaled
-BECLOMETHASONE, budesonide

28
Q

leukotriene receptor antagonists??

A

suppress effects of leukotrienes (which promote smooth muscle constriction, vessel permeability, and inflammatory responses directly)
-decreases bronchoconstriction
-indication: maintenance therapy in chronic asthma, second line therapy
-adults, children 5 and above
-oral
side effects: headache and GI, arthralgia, and myalgia, neuropsychiatric effects (depression, suicidal thoughts)
interactions?? various drugs!!! aspirin, eryhtomycin, warfarin
ex. ZAFIRLUKAST

29
Q

leukotriene receptor antagonists are NOT….

A

recommended for pts going through acute changes, will mimic signs and symptoms

30
Q

opioids for RSV?

A

low doses of opioids very effective in decreasing perception of dyspnea (morphine sulphate)

  • promote comfort, decrease RR effort to calm them and help relax
  • used as adjunct but do not know how, exact mechanism unknown
31
Q

antitussives?

A

cough suppressents, ONLY WHEN ONGOING DRY NONPRODUCTIVE COUGH

  • cannot give with secretions and mucus
  • opioid based (codeine)
32
Q

expectorants?

A

reduce viscosity of secretions for easier removal

33
Q

mucolytics?

A

break down chemical structure of mucus for easier removal by coughing

34
Q

risk factors for infants developing severe RSV?

A

being less than 6 weeks old

  • prematurity under 6 months of age
  • underlying resp or cardiac conditions
  • immunocompromise
35
Q

RSV is transmitted from exposure to….

A

contaminated secretions, can live on fomites for several hours!! hands for 30 mins

36
Q

pathophysiology of RSV?

A

affects epithelial cells of resp tract

  • cilitaed cells well, protrude into lumen, lose their cilia
  • fusion of infected membrane with cell membranes of adjacent epithelial cells—> forming giant cell
  • bronchial mucosa swells, lumins subsequently filled with mucus and exudate
  • walls of bronchi and bronchioles infiltrated with inflammatory cells
  • hyperinflation, obstructive emphysema (overinflation from air trapped) resulting from partial obstruction, patchy areas of atelectasis
37
Q

a single dose of bronchodilator is often prescribed and then…

A

if symptoms improve, it is condinued

38
Q

prevention of RSV?

A
  • palivizumab, monoclonal antibody given monthly in IM injection during RSV symptoms
  • lyophilized powder form of palivizumab should be admin within 6 hrs of being reconstitued with sterile water