Bronchiectasis and CF

Question 0

Causes of bronchiectasis

Answer 0

CF, Young’s, PCD/Kartagener’s, post viral (measles, pertussis etc), AI, obstruction, aspergillosis, idiopathic

Question 1

Main organisms causing bronchiectasis

Answer 1

H.influenzae, S.pneumoniae, S.aureus, P.aeruginosa

Question 2

CXR in bronchiectasis

Answer 2

Cystic shadows, thickened bronchial walls “tramline and ring shadows”

Question 3

Mutation causing CF

Answer 3

CFTR gene on chromosome 7 for Cl- channel

Question 4

Diagnosis of CF

Answer 4

Sweat test. Na+ and Cl- >60mmol/L

Question 5

General tests in CF

Answer 5

FBC, U&E, LFT, clotting, vit A D E levels, annual GTT, aspergillus serology, faecal fat analysis, sputum culture, CXR, abdo USS

Question 6

Median survival for CF in the UK

Answer 6

~40 years