brief brain tumours Flashcards
1
Q
mets
A
- most common CNS tumour
tumours that spread
- lung
- breast
- bowel
- melanoma
- kidney
2
Q
glioblastoma multiforme
A
- most common primary tumour
- poor px - less 1 yr
- solid
- central necorsis
- enhancing rim
- disruption of blood brain barrier -> vasogenic oedema
- pleomorphic tumour cells border necrotic areas
3
Q
mx of glioblastoma multiforme
A
surgery
post op chemo +- radio
dexamethasone - oedema
4
Q
meningioma
A
- second most common brain tumour in adults
- benign
- next to dura
- sx by compression
- located at the falx cerebri, superior sagittal sinus, convexity or skull base.
- Spindle cells in concentric whorls and calcified psammoma bodies
5
Q
ix for meningioma
A
contrast CT and MRI
6
Q
mx of meningioma
A
observation
radiotherapy
surgical resection
7
Q
vestibular schwannoma
A
- aka acoustic neuroma
- benign - from 8th CN
- in cerebellopontine angle
- hearing loss, facial nerve palsy, tinnitis
- bilateral in neurofibromatosis 2
- Antoni A or B patterns are seen. Verocay bodies (acellular areas surrounded by nuclear palisades)
8
Q
rx of vestibular shwannoma
A
observation
radiotherapy
surgery
9
Q
pilocystic astrocytoma
A
- most common primary brain tumour in children
- Rosenthal fibres (corkscrew eosinophilic bundle)
10
Q
medulloblastoma
A
- aggressive paediatric brain tumour
- from infratentorial compartment
- Small, blue cells. Rosette pattern of cells with many mitotic figures
11
Q
mx of medulloblastoma
A
surgery
chemo
12
Q
ependymoma
A
in 4th ventricle
may cause hydrocephalus
perivascular pseudorosettes
13
Q
oligodendroma
A
benign
slow growing
frontal lobes
calcifications - fried egg appearance
14
Q
haemangioblastoma
A
vascular tumour of cerebellum
von hippel-lindau
foam cells, high vascularity
15
Q
craniopharyngioma
A
- paediatric
- supratentorial tumour
- solid/cystic
- hormonal disturbance, hydrocephalus, bitemporal hemianopia
18
Q
A
meningioma
19
Q
A
glioblastoma
