Breastfeeding Flashcards
1
Q
What is RID?
A
Relative infant dose
2
Q
How do you calculate RID?
A
Infant dose/mother dose
3
Q
What is the milk to plasma ratio?
A
The ratio of the concentration of drug in the mother’s milk / concentration in mother’s plasma
4
Q
Why is the milk to plasma ratio poor?
A
Provides relative rate of entry into milk not an absolute clinical dose to infant
5
Q
What are the best properties for a drug given to a breastfeeding mother? (3)
A
Highly protein bound
Short half life
Low bioavailability
