Breast Cancer Flashcards

1
Q

Where do breast cancers usually begin devloping?

A

In the ducts

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2
Q

What are the signs and symptoms of breast cancer?

A

A new lump
Nipple change
Skin change
Unusual nipple discharge
Shape change

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3
Q

What are the risk factors for developing breast cancer?

A

Non-modifiable
- Being a woman
- Aging
- Family history
- BRCA1 and BRCA2 genes

Modifiable
- Obesity
- High alcohol consumption
- Sedentary lifestyle

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4
Q

What is ductal carcinoma in situ?

A

When cancer cells are in the breast duct, have not yet spread outside the duct and into surrounding breast tissue

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5
Q

What is invasive ductal carcinoma?

A

When cancer cells invade into surrounding breast tissue from the breast duct and have the ability to metastasize to lymph nodes and other organs

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6
Q

What is inflammatory breast cancer?

A

An aggressive breast cancer characterised by progressive inflammation of the breast, turning from pink to red or purple, becoming swollen and heavy

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7
Q

What screening options are there for breast cancer?

A

Mammograms
- Breast tissue X-ray

Ultrasound
- Especially in younger women or women with dense breast tissue

MRI

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8
Q

What is the triple test for breast cancer?

A

History and physical exam

Imaging

Biopsy

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9
Q

What are some treatment options for berast cancer?

A

Surgery
- Lumpectomy
- Partial or total mastectomy +/- reconstruction

Chemotherapy

Radiotherapy

Targeted therapies
- Monoclonal antibodies
- Antibody-drug conjugates

Endocrine therapy
- Blocks oestrogen production stunting breast cancer growth

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