Breast - Benign Disease Flashcards

1
Q

Failure of development of the breast at puberty is uncommon- this is usually related to what condition?

A

Turner’s syndrome

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2
Q

When is a fibroadenoma most likely to be diagnosed?

A

In the early reproductive years, most commonly the 3rd decade

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3
Q

What are the 3 potential outcomes of a fibroadenoma?

A

1/3rd regress, 1/3rd stay the same, 1/3rd get bigger

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4
Q

When should a fibroadenoma be excised?

A

If it is growing or changing, or if it is > 3cm

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5
Q

Fibrocystic change can affect women of any reproductive age, but is most common when?

A

Aged 40-50

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6
Q

What are the main symptoms of fibrocystic change?

A

A discrete lump or lumpy breasts, and cyclical pain

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7
Q

What benign breast lesion is this describing: a circumscribed lesion composed of cell types normal to the breast but present in an abnormal proportion or distribution?

A

Hamartoma

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8
Q

Why may sclerosing lesions of the breast mimic carcinoma?

A

Because the mass can feel irregular and they are histologically similar

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9
Q

Which sclerosing lesions of the breast are not malignant per se but may show epithelial proliferation, and in situ or invasive carcinomas may occur within them?

A

Radial scar and complex sclerosing lesion

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10
Q

What is the difference between a radial scar and a complex sclerosing lesion?

A

Radial scar = 1-9mm, complex sclerosing lesion = > 9mm

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11
Q

What treatment is required for sclerosing lesions of the breast?

A

Excision

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12
Q

What is usually the cause of fat necrosis of the breast? What medication may be implicated?

A

Local trauma / warfarin

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13
Q

How does fat necrosis usually present?

A

A hard, painless lump

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14
Q

What is the biggest risk factor for developing duct ectasia?

A

Smoking

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15
Q

When does duct ectasia typically occur?

A

Around the menopause

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16
Q

Breast pain, bloody and/or purulent nipple discharge and nipple retraction/distortion are features of what benign breast condition?

A

Duct ectasia

17
Q

Which benign breast condition may be described as feeling like a ‘bag of worms’?

A

Duct ectasia

18
Q

What are the two main aetiologies behind acute mastitis and breast abscess?

A

Lactation and duct ectasia

19
Q

Lactational mastitis or breast abscess is most likely to be caused by which organism?

A

Staph Aureus

20
Q

How should breast mastitis be treated? What additional treatment is required for a breast abscess?

A

Antibiotics (usually flucloxacillin) / aspiration or incision and drainage is also required for an abscess

21
Q

What is the advice given regarding breastfeeding to women with lactational mastitis or breast abscess?

A

Continue breastfeeding

22
Q

If a case of mastitis is unresponsive to antibiotic therapy, and is spread all over the breast, what other diagnosis must be considered?

A

Inflammatory breast cancer

23
Q

What are some measures which may improve cyclical mastalgia?

A

A firm, well-fitting bra, exercise, evening primrose oil

24
Q

What may be a useful treatment for non-cyclical mastalgia?

A

Topical NSAIDs

25
What is the most likely diagnosis for the development of a firm, vertical, cord-like structure after breast trauma?
Mondor's disease (phlebitis of superficial veins)
26
How is Mondor's disease managed?
It will usually resolve spontaneously in 8-12 weeks
27
What may differentiate a Phyllodes tumour from a fibroadenoma?
Occurs in older women and is often larger
28
How should a Phyllodes tumour be treated?
Excision with 1cm margins
29
Why should those who have had a Phyllodes tumour be closely followed up?
They are prone to local recurrence
30
How do intraductal papillomas usually present?
Nipple discharge which may or may not be bloody
31
How should breast papillomas be treated?
Excision with 1cm margins