Breast - Assessment of Disease Flashcards

1
Q

What are the 3 areas of triple assessment for breast disease?

A

Clinical, imaging, pathology

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2
Q

For women aged < 35, what imaging investigation(s) should be performed in the initial assessment of any breast symptom?

A

Ultrasound

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3
Q

For women aged > 35, what imaging investigation(s) should be performed in the initial assessment of any breast symptom?

A

Ultrasound and mammogram

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4
Q

When should women aged < 35 ever receive a mammogram?

A

If they have been diagnosed with breast cancer

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5
Q

What is the most important imaging technique for women who are symptomatic of breast disease?

A

Ultrasound

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6
Q

Why are mammograms more sensitive in women aged > 35?

A

They have less fibro-glandular tissue and more fatty tissue

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7
Q

Calcification on mammography is usually a sign of what?

A

DCIS

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8
Q

90% of spiculate masses on mammography are what?

A

Invasive cancers

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9
Q

Central necrosis on mammography is usually a sign of what?

A

DCIS

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10
Q

Stellate lesions on mammography are usually a sign of what?

A

Invasive carcinoma

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11
Q

Breast lumps have to be greater than what diameter to be identified on ultrasound or mammography? What investigation can be used to identify breast lumps as small as 1mm?

A

5mm / MRI

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12
Q

What screening do patients with BRCA mutations receive?

A

Annual breast MRI and mammogram up to the age of 50, then join the regular screening programme

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13
Q

If imaging finds a cystic breast lump, what should be done next?

A

Aspiration of the lump

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14
Q

If imaging finds a cystic lump, and this is aspirated but a residual mass remains, what should be done next?

A

Core needle biopsy

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15
Q

If imaging finds a cystic lump, and bloody fluid is aspirated, what should be done next?

A

Send for cytology

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16
Q

What is the most common way of obtaining a sample for breast cytology?

A

FNA

17
Q

What is the most common way of obtaining a sample for breast histopathology?

A

Core needle biopsy

18
Q

How is a core needle biopsy carried out on a breast lump which is not palpable?

A

It can be ultrasound, x-ray (stereotactic) or MRI guided

19
Q

What is the difference between B5a and B5b histopathology samples?

A

B5a = carcinoma in situ, B5b = invasive carcinoma

20
Q

What is the main advantage of histopathology over cytology for breast disease?

A

Only histopathology can determine between carcinoma in situ and invasive carcinoma