breast Flashcards
nipple bleeding in younger woman
intraductal papilloma
usually no discrete mass
if under 35, USS better than mma
what is trastuzumab?
mab aka herceptin
contraindicated in heart disease
most common breast cancer?
invasive ductal carcinoma
where does pagets disease metastasise to?
axillary lymph nodes!!
halo sign on mammogram, soft fluctuant mass,
cyst
how does duct ectasia present?
slit like nipple retraction
green brown nipple discharge
give example of aromatase inhibitors?
anastrazole
what are side effects of aromatase inhibitors?
osteoporosis - bisphosphonates alendronate assess BMD first and then regularly
menopausal symptoms
how are axillary mets treated?
axillary radiotherapy
who is breast ca screening offered to?
47-73
mammogram every 3 years
breast discharge in teenager?
hormonal changes
how might implant rupture present?
snowstorm appearance on mammogram
what are the side effects of tamoxifen?
DVT
irregular bleeding
endometrial cancer
how do you treat post op in brca
radiotherapy
when would you use chemo in brca?
if mets to ln
when to remove fibroadenoma?
if >3cm, causing discomfort
what will be raised in inflammatory breast cancer?
ca 15-3
how does inflammatory breast cancer present?
swollen breast, no fever, discharge
when to prescribe abx in mastitis?
if systemic symptoms
fissure present
symptoms last over 12 hours
if woman wants breast conservation in brca, what can be given to shrink tumour?
neo-adjuvant chemo
what population is periductal mastitis common in?
smokers, recurrent infections
advise stop smoking
treat with co-amoxiclav
what type of chemo used in brca patients who are node positive?
FEC-D
how to differentiate duct ectasia from intraductal papilloma?
duct ectasia - multiple ducts
intraductal papilloma - discharge from single duct
which cancer is comedo necrosis most common in?
ductal carcinoma in situ
