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ABSITE 2019 > Breast > Flashcards

Breast Flashcards

1
Q

Hormone responsible for duct development

A

Estrogen

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2
Q

Hormone responsible for lobular development

A

Progesterone

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3
Q

Hormone responsible for breast swelling, growth of glandular tissue

A

Estrogen

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4
Q

Hormone responsible for increased maturation of glandular tissue, withdrawal causes menses

A

Progesterone

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5
Q

Hormones to cause ovum release

A

FSH, LH surge

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6
Q

Winged scapula, innervates serratus anterior

A

Long thoracic nerve

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7
Q

Weak adduction, innervates latissimus dorsi

A

Thoracodorsal nerve

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8
Q

Innervates pectoralis major and pectoralis minor

A

medial pectoral nerve

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9
Q

Innervates pectoralis major only

A

lateral pectoral nerve

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10
Q

Most commonly injured nerve w/ ALND and modified radical mastectomy

A

Intercostobrachial nerve (numbness in medial arm/axilla)

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11
Q

Blood supply to breast is from (4)

A

internal thoracic a
intercostal a
thoracoacromial a
lateral thoracic a

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12
Q

Valveless vein plexus that allows direct hematogenous metastasis of breast cancer to spine

A

Batson’s plexus

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13
Q

Primary axillary adenopathy

A

1 in lymphoma

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14
Q

What node status is + supraclavicular nodes

A

N3 disease

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15
Q

Most common bug in breast abscess

A

s. aureus

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16
Q

Noncyclical mastodynia, erythema of breast, creamy discharge from nipple

A

Periductal mastitis

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17
Q

Poland Syndrome

A

Hypoplasia of chest wall
Amastia
Hypoplastic sholder
No pectoralis muscle

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18
Q

Treatment of mastodynia

A 
Danazol
OCP
NSAIDs
Evening primrose oil
Bromocriptine
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19
Q

Mondor’s disease

A

Superficial vein thrombophlebitis of breast
Feels cordlike
Tx w/ NSAIDs

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20
Q

Which types of fibrocystic disease have to be resected due to cancer risk (2)

A

Atypical ductal
Lobular hyperplasia
**Does NOT need negative margins

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21
Q

Most common cause of bloody nipple discharge

A

Intraductal papilloma

22
Q

Prominent fibrous tissue compressing epithelial cells

A

Fibroadenoma

23
Q

What 3 criteria must be met in patient <40 w/ suspected fibroadenoma to observe

A

1) mass needs to feel clinically benign
2) US/Mammo consistent w/ fibroadenoma
3) FNA/CNBx to confirm fibroadenoma
If not 3/3 then requires excisional biopsy
If >40 then –> excisional biopsy

24
Q

Most aggressive subtype of DCIS

A

Comedo pattern - high risk for recurrence

25
Q

Treatment for DCIS

A

Lumpectomy and XRT

Need 1cm margins

26
Q

Treatment for Comedo type DCIS

A

Simple mastectomy and SLNB

27
Q

DCIS on mammogram

A

Cluster of calcifications on mammogram, not palpable

28
Q

LCIS on mammogram

A

No calcifications, not palpable

29
Q

What type of cancer do patients w/ LCIS develop

A

Ductal CA

30
Q

Margins needed for LCIS

A

Do NOT need negative margins

31
Q

LN Levels Mastectomy

A

I: lateral to pec minor
II: deep to pec minor
III: medial to pec minor

32
Q

Nodes between pec major and pec minor

A

Rotter’s nodes

33
Q

Most common site for distant metastasis

A

bone (lung, liver, brain)

34
Q

BRCA I lifetime risk
Female Breast cancer
Ovarian Cancer
Male Breast Cancer

A

60
40
1

35
Q

BRCA II lifetime risk
Female Breast cancer
Ovarian Cancer
Male Breast Cancer

A

60
10
10

36
Q

BRCA screening

A

yearly mammogram and breast MRI starting at age 25

yearly pelvic exam + US, CA-125 starting at age 25

37
Q

Receptor blocker for Her2/neu + breast cancer

A

Trastuzumab (Herceptin)

38
Q

Worse prognosis subtype of ductal cancer

A

Scirrhotic

39
Q

More favorable prognosis subtype of ductal cancer

A

medullary (increased lymphocytes)

40
Q

Treatment of Ductal Cancer

A

MRM

Breast conserving + post op XRT

41
Q

Worse prognosis sybtype of lobulcar cancer

A

Signet ring cells

42
Q

Treatment of Lobular cancer

A

MRM

Breast conserving + post op XRT

43
Q

Treatment of inflammatory cancer

A

Neoadjuvant chemo + MRM + adjuvant chemo/XRT

44
Q

Indication for SLNB

A

Tumors >1cm w/o clinical nodes

45
Q

Indication for XRT after mastectomy

A

advance nodal disease (>4 nodes, N2-N3)
skin/chest wall involvement
+ margins
T3-T4

46
Q

Who gets chemotherapy

A

> 1cm + negative nodes

+ nodes

47
Q

Occult breast cancer

A

axillary metastases w/ unknown primary

48
Q

Paget’s disease

A

scaly skin lesion on nipple, associated w/ DCIS or ductal CA

49
Q

Spread of phyllodes tumor

A

hematogenous

50
Q

Stewart-Treves syndrome

A

Lymphangiosacroma from chronic lymphedema following axillary dissection **presents w/ dark purple nodule or lesion on arm 5-10 years after surgery

ABSITE 2019 (8 decks)

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