Breast Flashcards
Outline triple assessment for Breast disease and the score system
-Clinical examination
-Imaging (USS and mammogram)
-Histology (biopsy)
Done via P score
Breast cyst character and shape
- Fertile women
- Fluctuate during menses
- Firm and mobile
Fibroadenoma character and shape
- 2nd most common
- Mobile “breast mouse”
- Can become GIANT fibroadenoma
Galactocele
Milk filled cyst periareola region
Duct Ectasia
- Commonly affects older women
- Dilated sub-areolar ducts
- Palpable mass behind areola
- Nipple changes and disharge
Management of mastitis - most common bacteria involved
- Heat and continue feeding, antibiotics 10-14 days
- Staph/Strep
What hormone is corrolated most with increased breast cancer risk
oestrogen
Most common 2 non-invasive breast cancers
- Ductal carcinoma in situ - PRECANCEROUS lesion
- Lobular carcinoma in situ (2nd most common)
Most common invasive carcinoma of the breast
Invasive ductal carcinoma (then lobular)
3 most common sites for breast metastasis
Bone, liver and lungs
Receptors targeted by tamoxifen and its most noted risk
- Oestrogen
- Endometrial cancer
MOA of anastrazole/letrozole and clinical indication
Selective aromatase inhibitors cut off tumors oestrogen supply
-Used in women post menopause
Main risk of Herceptin therapy
Cardiomyopathy
Tumor marker for breast cancer
CA15-3
Intraductal papilloma types, character and signs
-Definitive tests
Central type: Benign, near nipple associated with cyclical changes and bloody discharge
Peripheral type: Multiple in number found in younger women and more associated with malignancy
-Galactogram: can view milk ducts
