breast Flashcards
what are suspicious features of a breast lump
- craggy edge
- irregular
- tethering
- growing lump
- pmh breast ca
- skin dimpling
- nipple retraction
- blood stained discharge
what is the best way to take a biopsy?
US guided core biopsy
whats the equivalent background radiation for a mammogram?
2 months to a year
what is the lymphatic drainage of the breast?
axillary nodes
internal mammary nodes
what is the most common form of breast cancer?
invasive ductal carcinoma
what do the pathologists look at to determine the grade of a cancer?
- amount of gland formation
- the nucleus
- the mitotic activity
what can you give for HER2 positive cancers?
Herceptin
What can you give for ER positive cancers?
Tamoxifen
what can we use to estimate breast cancer survival?
predict score
what 3 components are used to determine a cancer’s stage?
- size
- lymph node involvement
- metastases
side effects of tamoxifen
menopausal symptoms eg hot flushes night sweats vaginal dryness loss of libido
also
dvt
endometrial thickening
cataracts
when does cyclical breast pain become most painful?
during the luteal phase (latter half) of the cycle
define adjuvant
therapy with is given after definitive treatment. The aim is to increase the chances of cure.
define neo adjuvant
treatment given before the main treatment with the aim of shrinking the tumour.