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Surgery > Breast > Flashcards

Breast Flashcards

1
Q

most common site of axillary lymph node metastases

A

lateral

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2
Q

most common site of metastasis

A

bone, lung, pleura, liver

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3
Q

carcinoma in situ associated with bilaterality

A

LCIS

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4
Q

common carcinoma in situ in premenopausal women

A

LCIS

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5
Q

True or false: tamoxifen and raloxifene are effective against DCIS and LCIS

A

raloxifene is NOT effective against DCIS and LCIS

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6
Q

surveillance for (+) BRCA: breast exam every __ months and mammography every __ months starting at age __

A

breast exam every 6 months and mammography every 12 months starting at age 25

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7
Q

annual mammographic screening starting at age

A

40

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8
Q

True or false: DCIS and LCIS are anatomic precursors

A

LCIS is not an anatomic precursor

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9
Q

True or false: for DCIS, mastectomy and lumpectomy with adjuvant radiotherapy have similar mortality rate

A

true

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10
Q

True or false: for DCIS, mastectomy and lumpectomy with adjuvant radiotherapy have similar rates of local recurrence

A

lumpectomy with adjuvant radiotherapy has higher rate of local recurrence

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11
Q

Differential diagnosis for Paget’s disease of the nipple, and how to differentiate

A

Paget’s disease: (+) CEA

superficial spreading melanoma: (+) S-100

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12
Q

where are the Paget cells located in the skin?

A

rete pegs

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13
Q

Signet ring cells and Indian file configuration are found in what type of breast cancer?

A

invasive lobular carcinoma

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14
Q

True or false: invasive lobular carcinomas are unilateral

A

multifocal, multicentric and bilateral

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15
Q

Medullary carcinoma can mimic

A

fibroadenoma

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16
Q

Medullary carcinoma is associated with BRCA 1 or BRCA 2?

A

BRCA 1

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17
Q

Mammography: visualizes upper outer quadrant and axillary tail of Specne

A

mediolateral oblique

18
Q

Mammography: visualizes medial aspect of breast

A

craniocaudal

19
Q

Mammography: images the greatest volume of breast tissue

A

mediolateral oblique

20
Q

Mammography: permits greater breast compression

A

craniocaudal

21
Q

Mammographic mimickers of breast cancer

A

radial scars, fibromatosis, granular cell tumor, fat necrosis

22
Q

True or false: multifocality is a contraindication to breast conservation surgery

A

Multicentricity
Prior radiation therapy to the breast or chest wall
Involved surgical margins or unknown margin status after re-excision
Scleroderma or lupus erythematosus

23
Q

Treatment: Her-2/neu (+)

A

doxorubicin, cyclophosphamide, paclitaxel

24
Q

Treatment: Her-2/neu (-)

A

trastuzumab

25
Q

Treatment: breast cancer in second trimester of pregnancy

A

MRM

26
Q

Treatment: breast cancer in third trimester of pregnancty

A

lumpectomy with axillary node dissection

27
Q

Most common type of male breast cancer

A

DCIS

28
Q

Metastasis in cystosarcoma phylloides

A

vascular

29
Q

True or false: cystosarcoma phylloides spreads to axillary lymph nodes

A

cystosarcoma phylloides DOES NOT spread to axillary lymph nodes

30
Q

Rotter’s node

A

interpectoral group (level II)

31
Q

Gynecomastia: (+) redundancy

A

Grade III

32
Q

Malignant risk of sclerosing adenosis and intraductal papilloma

A

none

33
Q

True or false: cancers associated with BRCA1 are well differentiated and hormone receptor positive

A

poorly differentiated and hormone receptor negative

34
Q

True or false: cancers associated with BRCA1 are unilateral

A

bilateral

35
Q

True or false: cancers associated with BRCA2 are well differentiated and hormone receptor positive

A

true

36
Q

True or false: papillary breast carcinoma have high rate of axillary metastasis

A

low rate

37
Q

true or false: breast pain is associated with cancer

A

benign disease

38
Q

chemotherapy for breast cancer

A

doxorubicin-containing

39
Q 
Most common subtype:
A. ER+ and/or PR+, HER2-
B. ER+ and/or PR+, HER2+
C. ER-, HER2+
D. ER-, PR-, HER2-
A

ER+ and/or PR+, HER2-

40
Q

True or false: cystosarcoma phyllodes are poorly demarcated

A

well-demaracted

Surgery (17 decks)

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