Breast Flashcards
How does Phyllodes spread?
What does it stain for?
hematogenously
actin vemectin
atypical ductal/lobular hyperplasia on core needle, next step?
Excisional biopsy
What is the full treatment for inflammatory breast cancer
Neoadjuvant
Total mastectomy with ax dissection
Rads
Adjuvant
Purpose of tissue expanders?
Maintain volume while radiation is done prior to saline implant
Indications for skin biopsy on breast/ dg criteria for inflam breast cancer
Rapid onset of breast erythema, edema, and/or peau d’orange
Duration of no more than 6 months
Erythema occupying at least one-third of the breast
Invasive carcinoma on pathology
Green nipple discharge, think….
fibrocystic changes
The American Society of Breast Surgeons guidelines for selection of patients for PBI includes
The American Society of Breast Surgeons guidelines for selection of patients for PBI includes age ≥45 for invasive disease, ≥50 for in situ disease, tumor size ≤3 cm, resection to negative microscopic margins, and negative axillary nodal status.
Mass felt at lumpectomy site 6 months after lumpectomy, next step?
Mammogram and ultrasound
Z11 trial significance
showed no survival difference between sentinel lymph node biopsy alone versus axillary dissection for patients with T1 or T2 breast cancer with no clinical evidence of lymph node involvement, breast-conservation surgery, and fewer than three positive sentinel lymph nodes
Neoadjuvant vs adjuvant for breast cancer, what is the difference in results
increased rates of breast conservation
Fine, linear, pleomorphic calcifications are concerning for what
DCIS
What lifetime risk is high risk for breast cancer? Gen pop percent?
20; 12
What are the mild, moderate and high risk factors for breast cancer history
Factors that indicate a mildly elevated risk (relative risk <2) include early menarche, late menopause, nulliparity, proliferative benign disease, obesity, alcohol use, and hormone replacement therapy. Risk factors that indicate a relative risk for breast cancer of between 2 and 4 include age older than 35 years at first birth, a first-degree relative with breast cancer, and prior breast cancer. Factors that indicate a relative risk of greater than 4 include pathogenic gene mutations like BRCA1 and BRCA2, mantle radiation between the ages of 10 and 30, or high-risk benign breast lesions such as lobular carcinoma in situ and atypical hyperplasia, especially in patients with a family history of breast cancer.
At what age is breast cancer risk high in association with mantle radiation
10-30
Surgical treatment for inflammatory breast cancer
Modified Radical
Name the major structures of ax dissection/ borders
Borders of axillary dissection
