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12. Chemotherapy > Brands/Generics/Class > Flashcards

Brands/Generics/Class Flashcards

1
Q

Anzemet

  • Forms
  • Class
A

Dolasetron

  • Form: IV & PO
  • Class: 5-HT3 Serotonin Receptor Inhibitors
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2
Q

Kytril
Sancuso

  • Form
    • Sancuso
    • Kytril
  • Class
A

Granisetron

  • Form IV/PO
  • Sancuso: Transdermal 1 patch Q24-48H b/4 chemo. Can be worn for 7 days. Avoid sun
  • Class: 5-HT3 Serotonin Receptor Inhibitors
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3
Q

Zofran
Zuplenz

  • Form
  • Class
A

Odansetron

  • Zofran IV/IM/PO/ODT
  • Zuplenz: thin strip melts on tongue
  • Class: 5-HT3 Serotonin Receptor Inhibitors
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4
Q

Aloxi

  • Form
  • Half life
  • Class
A

PaLONosetron

  • IV/PO
  • LONg t1/2. Use this if worry ~ QT
  • Class: 5-HT3 Serotonin Receptor Inhibitors
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5
Q

Decadron

A

Dexamethasone

  • Corticosteroids
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6
Q

Medrol

A

Methylprednisolone

  • Corticosteroids
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7
Q

Emend

  • Metabolize
  • Class
  • Use in combo:
A

Fosaprepitant (pro-drug): IV
Aprepitant PO

  • Rapidly convert to aprepitant
  • Class: Neurokinin-1-receptor antagonists => working by blocking substance P
  • Used in combo with corticosteroid or 5HT3 inhibitors
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8
Q

Marinol

  • Class
  • Storage
  • Frequency
  • CS:
A

DRONabinol

  • Class: Cannabinoids
  • Refridgerated
  • TID-QID
  • CS: III
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9
Q

Cesamet

  • Class
  • Storage
  • Frequency
  • CS
A

NaBilone

  • Class: Cannabinoids
  • Non-refrigerated
  • BID
  • CS: II
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10
Q

Reglan

  • Form
  • MOA
  • Give w/ what to reduce what SEs
A

Metoclopramide

  • PO/IV/IM
  • MOA: Block dopamine in brain
  • Give w/ Benadryl to reduce extrapyramidal SEs
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11
Q

Diphenhydramine

A
  • Benadryl

- Class: Antihistamines

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12
Q

Atarax

  • Class
A

HyDROXyzine

  • Class: Antihistamines
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13
Q

Lorazepam

  • Class
A

Ativan

  • Class: Benzodiazepines
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14
Q

Alprazolam

  • Class
A

Xanax

  • Class: Benzodiazepines
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15
Q

Epogen
Procrit

  • Indication:
  • Dose/Form/Frequency
  • Exp of Multi-vial
A

Erythropoietin

  • Indication: for chemo induced anemia
  • 150-300 units/kg SC/IV 3x/wk
  • Multi-dose vials: discard 21 days after initial entry
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16
Q

Aranesp

  • Indication:
  • Dose/Frequency
    • Counseling on bottle
  • Storage:
  • – Epogen and Aranesp —-
  • CI
  • Warning
  • Monitoring
A

DARbepoetin alfa

  • Indication: for chemo induced anemia
  • 2.25 mg/kg SC weekly
  • Do not shake
  • Refrigerate/protect from light

—— Epogen, Procrit, Aranesp—-
- CI: Uncontrolled HTN
- Warning: CVD, thromboembolic event, tumor progression.
D/C if Hgb b/w 10-12.
- Monitor:
BP, CBC w/ diff, Hgb
Ferritin: low (give iron, B12, and folate)

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17
Q

Neumega

  • Indication:
  • MOA:
  • Dose/Route
  • Monitor
A

Oprelvekin (Oh Prel ve kin)

  • I: chemo induced thrombocytopenia
  • MOA: Interleukin -11 (IL-11) is a thrombopoietic growth factor that increases platelet production
  • Dose: 50 mcg/kg SQ QD start 6-24H after chemo & cont until platelets count is >50000 cells/mL
  • Monitor: Fluid retention and electrolyte => CHF and arrhythmia
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18
Q

Neupogen

  • Indication
  • Storage
  • Dose
  • SEs
A

FilgrasTIM GCSF

  • I: granulocytes to tx neutopenia. Use to reduce febrile neutropenia after chemo
  • Refrigerate: use w/in 24H if at RT
  • D: 5mcg/kg/day ingle dose SC or IV infusion over 15-30min
  • SE: bone pain
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19
Q

Neulasta

  • Indication:
  • Storage
  • Dose
  • SEs
A

PegfilgrasTIM

  • I: granulocytes to tx neutopenia. Use to reduce febrile neutropenia after chemo
  • Refridgerate/protect from light. Use w/in 48H at RT
  • Dose: 6mg SC x 1 each chemo cycle
  • SE: bone pain
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20
Q

Kayexalate

A

Sodium polystyrene sulfonate (SPS)

  • I: Shift K intracellular
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21
Q

Chemo drugs are never in mg/kg, it’s in:

A
  • mg/m2
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22
Q

One inch = ? cm

A

1’ = 2.54 cm

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23
Q

1kg = ? lb

A

1 kg = 2.2 pounds

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24
Q

PLANTINol

  • Class:
  • SEs
    • Cause most:
  • Give w/ what as ppx to prevent nephrotoxic
  • Give what for promote excretion
  • Reduce nephrotoxicity by:
A

CisPlatin

  • Alkylating agents

SEs

  • Nephrotoxicity
  • Ototoxicity
  • Peripheral Neuropathy
  • Electrolyte imbalance: decr PO4, K, Ca, Mg
  • Cause MOST GI upset
  • Amifostine: given as ppx to prevent nephrotoxicity
  • Manitol: promote excretion

Reduce Nephrotoxicity by:

  • Hydration: 2-3L NS over 8-12H
  • Mannitol 25-50g IV b/4
  • Amifostine: start b/4 chemo
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25
Q

Ethyol

  • Indication
  • SEs
  • D/C which med:
A

Amifostine

  • Give as ppx to prevent nephrotoxicity in cisplatin

SEs

  • Severe HyperTN
  • Infusion rxn: flushing, chills, hiccups, sneezing, n/v
  • D/c all HTN med
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26
Q

Paraplatin

  • Is amifostine indicated for this drug?
A

Carboplatin

  • Amifostine is no indicated => cause less nephrotoxicity
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27
Q

Eloxatin

  • Indication
  • SE
A

OxaliPtin

  • Use for colorectal cancer w/ 5-FU + leucovorin
  • SE: Peripheral neuropathy
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28
Q

Myleran

  • SEs
A

Busulfan

SEs
- Increase uric acid (Hyperuricemia):
Watch for other drugs (thiazide, loop, niacin, low dose ASA)
- Pulmonary fibrosis (SOB & chest x-ray)
- Hyperpigmentation of skin: stop ASAP and give steroid
- SZ
- BMS

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29
Q

Cytoxan

  • Prevent hemorhagic cystitis
  • SEs
  • Monitor
A

C(4)yclophoSphamide

Prevent hemorhagic cystitis

  • Mesna to bind to acrolein
  • Hydration

SEs

  • Hemorhagic cystitis: cause by acrolein
  • Renal tubular necrosis
  • Hepatotoxicity
  • Cardiac SEs
  • Alopecia
  • Sterility

Monitor
- CBC, plt, BUN, UA, Electrolytes, SrCr

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30
Q

Ifex

  • Mesna
A

Ifosfamide

  • Mesna comes with the ifosfamide package
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31
Q

Mesna indication

A
  • Bind to acrolein as ppx to prevent hemorhage cystitis in cyclophosphamide and ifosfamide
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32
Q

BiCNU

  • Indication:
  • SEs
A

C(2)ARMustine

  • I: lipid soluble => treat cns malignancies (brain tumor)

SEs

  • Hepatotoxicity
  • Nephrotoxicity
  • Pulmonary fibrosis => CAR = carbon dioxine = lung toxic
  • Bone marrow suppression
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33
Q

CeeNu

  • Indication:
  • SEs
A

Lomustine

  • I: lipid soluble => treat cns malignancies (brain tumor)

SEs

  • Hepatotoxicity
  • Nephrotoxicity
  • Bone marrow suppression
  • Pulmonary fibrosis
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34
Q

Zanocar

  • SEs
  • Dose limiting due to
A

StrEptozocin

SEs

  • Pancreatic damage
  • Nephrotoxicity
  • Extravasation
  • Dose limiting - 90% get DM I
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35
Q

Alkeran

  • SEs
A

Melphalan

SEs

  • Fertility Impairment
  • BMS
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36
Q

Which drug cause fertility imp and no pharmacist can work while pregnant

A
  • Melphalan (Alkeran)
  • Mechlorethamine (Mustargen)
  • Altretamine (Hexalen)
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37
Q

Mustargen

  • SEs
A

mEchlorethamine

SEs

  • Extravasation: severe necrosis => tx w/ Na thiosulfate
  • Fertility impairment
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38
Q

Hexalen

  • Route
  • Indication
  • SEs
  • MOAIs:
A

Altretamine

  • PO
  • I: tx ovarian cancer

SEs

  • Peripheral Neuropathy
  • Fertility Impairment
  • MOAIs: may cause severe othostatic hypoTN
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39
Q

Mutalane

  • SEs in Pediatric
  • Monitor:
  • Give with MOAIs
A

Procarbazine

  • SEs in Ped: tremors, convulsion
  • Disulfiram rxn
  • M: CBC, renal, hepatic
  • MOAIs: high tyramines or MOAIs = fatal HTNsive crisis
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40
Q

Drugs that have MOAI effects

A
  • Altretamine (Hexalen)

- Procarbazine (Mutalane)

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41
Q

Drugs Cause Tumor Lysis Syndrome

A
  • Bendamustin (Trenda)
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42
Q

Anti-Metabolites

A

Anti-Metabolites

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43
Q

Folinic acid

  • Indication
A

Leukovorin

  • Give with methotrexate as a rescue drug to save the good cells
  • Give with 5-FU to increase its action. When used together, 5-FU works better, thus use less amt of 5-FU
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44
Q

Glucarpidase (Voraxaze)

  • Indication
A
  • An injectable carboxypeptidase enzyme that breaks down MTX in the body so the drug can be easily eliminated when the kidneys are not working properly
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45
Q

5-FU
Adrucil

  • INR
  • SEs
A

FluOrouracil

  • Increase INR

SEs

  • Hand & foot syndrome
  • Mucositis
  • Neurotoxiticy
  • Alopecia
  • Ocular toxicity
  • Photosensitivity
  • Light sensitive
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46
Q

Light sensitive drugs

A
  • Methotrexate
  • 5-FU
  • Cisplatin
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47
Q

Xeloda

  • Indication
  • Dose:
  • Administration
A

Capecitabine - prodrug of 5-FU

Indication

  • Metastatic breast cancer resistant to paclitaxel
  • 1st line for metastatic colorectal carcinoma
  • Dosage Form: PO 150 mg and 500 mg Tab
  • D: Cyclical 1250 mg/m2 BID - 2 wk on 1 wk off
  • Take with water w/in 30 min after AM and PM meals
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48
Q

Purinethol
Purixan

  • SEs
  • DDIs
A

Mercaptopurine (6-MP)

SEs:

  • Hepatotoxicity
  • Hyperuricemia
  • Hyperpigmentation of skin
  • Rash
  • Mucositis
  • Diarrhea

DDIs

  • Allopurinol: will increase 6-MP. 6MP active metabolite is catalyzed by xanthine oxidase. Allopurinol is a xanthine oxidase inhibitor
  • Bactrim: inc 6-MP
49
Q

Cytosar

  • SEs
A

Cytarabine => PPPH

SEs

  • Conjunctivitis/CNS
  • Hepatotoxicity
  • Pancreatitis
  • Pulmonary tox
  • Peripheral neuropathy
  • Cytarabine syndrome: fever, myalgia, bone pain, occasional chest pain, rash
  • *CNS changes when used IV intrathecal
  • *Vision change: conjunctivitis & Keratitis => use dexamethasone eye drops w/ high doses
50
Q

Fludara

  • SEs
A

FludarabiNe

SEs

  • Sig immunosuppression “AIDS in a bottle”
  • Neurotoxicity: irreversible blindness, coma, death
51
Q

Trenda

  • Diluent use:
  • Storage
  • Solution color
  • SEs
A

BENdaMustin

  • D: 100mg/m2 IV on day 1 & 2 of a 28 days cycle up to 6 cycles
  • Diluent: NS
  • Stable 24H refrigerated or 3H RT
  • Colorless/clear lightly yellow soln
  • Protect from light

SEs

  • Myelosuppression
  • Infusion rxn & anaphylaxis
  • Tumor Lysis syndrome
52
Q

Rheumatrex
Otrexup
Trexall

  • Indication
  • Dose
  • SEs
  • Drugs impair MTX excretion
  • Monitor
  • Rescue drugs
A

Methotrexate

Dose

  • RA: 7.5mg/wk PO single dose or 2.5 mg PO Q12H x 3 doses given once weekly. Max 20mg weekly
  • Intrathecal - 12 mg
  • High dose: 500-12000 mg/m2 IV q2-3wks

SEs

  • Hepatotoxicity
  • Renal insufficiency: keep urine alkaline w/ NaHCO3 to prevent crystallization & well hydrated to avoid renal tox
  • Pulmonary tox
  • Photosensitivity => use sunscreen
  • Light sensitive
  • Mucositis
  • Folic acid antagonist => give 1mg/d

Impair MTX excretion:
- NSAIDs, ASA, Penicillins, Bactrim, PPI => stop b/4 MTX

Monitor
- LFT, Renal fxn, CXR, and CBC

Rescue

  • Leukovorin
  • Glucarpidase
53
Q

Antibiotics

A

Antibiotics

54
Q

Bleomycin

- SEs

A
  • Blenoxane

SEs

  • Pulmonary tox: non productive cough. Occur when acc dose > 450-500mg. Never give > 500mg life time
  • Skin tox: hyper-pigmentation: red spots that are not uniform
55
Q

Adriamyacin
Doxil

  • SEs
  • Accumulate life time dose
A

DoxoRUbicin

SEs:

  • CHF: irreversible due to Fe
  • Urine color: red
  • ** Preg Cat D
  • Extravasation: apply COLD (december is cold)

Accumulate life time dose
- 550 mg/m2

56
Q

DaunoXone: Liposomal
Cerubidine: Conventional

  • SEs
  • Accumulate life time dose
A

DaunoRUbicin

SEs:

  • CHF: irreversible due to Fe
  • Urine color: red
  • Extravasation: apply COLD (december is cold)

Acc life time dose
- 900 mg/m2

57
Q

Zinecard

  • Indication
A

Dexrazoxane

  • Iron chelator: protects against cardiotoxicity of doxorubicin and daunorubicin
  • Comes in liposomal form => less toxicity
58
Q

Valstar

  • Turn urine color:
  • SEs:
A

ValRUbicin

  • Transient urine discoloration RED
  • Irritable bladder symptoms
59
Q

Cosmegen

  • SEs
  • CIs
A

DACtomycin

  • Extravasation ass w/ severe necrosis
  • CI: active chicken pox or herpes zoster
60
Q

Novoantrone

  • SEs
A

Mitoxantrone

  • Turn urine to a blue/blue green color and the white part of your eyes turn a bluish colors => this is normal and not a cause for concern
61
Q

Plant Alkaloids

A
  • Docetaxel, paclitaxel
  • Etoposide, Teniposide
  • Irinotecan, Topotecan
62
Q

Taxotere

  • SEs
A

Docetaxel

SEs

  • Hypersensitivity => premed w/ dexamethasone 8mg BID 3-5d, start 1 day prior
  • Fluid retention/Pulmonary edema => use lasix
63
Q

Taxol

  • SE
  • Tube to use
  • Diluent contains
  • CI:
A

PacliTAXel

  • SE: Hypersensitivity => PreMed
  • use NON-PVC tubing
  • Diluent contains: contain EtOH => disulfram rxn
  • CI: Castor oil
64
Q

Toposar

  • SEs
A

EtoPOside

  • Etoposide VP-16: cap refrigerate

SE
- HypoTN due to rapid infusion

65
Q

TeniPOside (Vumon)

  • SEs
A

Vumon

SE
- HypoTN due to rapid infusion

66
Q

Camptosar

  • SE
  • Early treatment
  • Late treatment
A

Ironotecan

SES
- Diarrhea & dehydration: life threatening
- Early: tx w/ atropine - anticholinergic
- Late: Loperimide: regardless of max dose
=> OTC max = 8mg
=> Rx max = 16 mg
=> Replenish fluid & electrolytes

67
Q

Hycamtin

  • SEs
A

Topotecan

SES
- Diarrhea & dehydration: life threatening
- Early: tx w/ atropine - anticholinergic
- Late: Loperimide: regardless of max dose
=> OTC max = 8mg
=> Rx max = 16 mg
=> Replenish fluid & electrolytes

68
Q

Vinka Plant Alkaloids

A

Vinka Plant Alkaloids

69
Q

Oncovin
Marqibo: liposome

  • SEs
A

VinCristine

SEs

  • Most *CNS tox
  • Peripheral neuropathy: most w/ vincristine
  • Constipation: start stool softener
70
Q

Velban

  • SEs
A

VinBlastine

SEs

  • *BMS
  • Peripheral neuropathy: most w/ vincristine
  • Constipation: start stool softener
71
Q

Navelbine

  • SEs
A

VinOrelbine

SEs:

  • Most *alopecia
  • Peripheral neuropathy: most w/ vincristine
  • Constipation: start stool softener
72
Q

Preparing Vinca Plant Akaloids

  • Label required:
A
  • Prepared only in small volume infusion bag for rapid IV infusion per nursing standards
  • Labeled “For IV USE ONLY - FATAL if given intrathecally”
73
Q

Dispensing Intrathecal Chemo

A
  • Labels for intrathecal route
  • No other chem/med dispense at the same time
  • The person ordered will review w/ pharmacist, verify his/her status w/ MD, fellow or chemo certified nurse by signing of the med
74
Q

Tyrosine Kinase Inhibitors

A

Tyrosine Kinase Inhibitors

  • Form: Only come in PO forms
  • SEs: Diarrhea and Nausea
75
Q

Gleevec

  • Class
  • SEs
  • DDI
  • Monitor
A

Imatinib

  • Class: Tyrosine kinase inhibitors
  • SEs: fluid retention
  • Substrate; strong inhibitor of 3A4
  • Monitor: CBC, LFT, wt gain
76
Q

Tarceva

  • Indication
  • Administration
  • SEs
A

ErLOtinib

  • Class: Tyrosine kinase inhibitors
  • Indication: lung & pancreatic cancer
  • Adm: 100-150mg PO on Empty stomach

SEs

  • Increase LFT
  • Pulmonary sx
  • GI bleeding
  • Corneal ulceration
77
Q

Tykerb

  • Class
  • Indication
A

Lapatinib

  • Class: Tyrosine kinase inhibitors
  • I: breast cancer
78
Q

Tasigna

  • Class
  • Indication
  • Watch out for
A

NilOTinib

  • Class: Tyrosine kinase inhibitors
  • I: Leukemia
  • Watch for QT prolongation
79
Q

Bosulif

  • Class
A

Bosutinib

  • Class: Tyrosine kinase inhibitors
80
Q

Iclusig

  • Class
A

Ponatinib

  • Class: Tyrosine kinase inhibitors
81
Q

Inlyta

  • Class
A

Axitinib

  • Class: Tyrosine kinase inhibitors
82
Q

CarBOXantinib (Cometriq)

  • Administration
  • Class
A

CarBOXantinib

  • Take on empty stomach = Empty BOX
  • Class: Tyrosine kinase inhibitors
83
Q

Sprycel

  • Class
A

Dasatinib

  • Class: Tyrosine kinase inhibitors
84
Q

Iressa

  • Class
A

Gefitinib

  • Class: Tyrosine kinase inhibitors
85
Q

PaZOpanib (Votrient)

  • Class
A

PaZOpanib

  • Class: Tyrosine kinase inhibitors
86
Q

SORAfenib (Nexavar)

  • Class
A

SORAfenib

  • Class: Tyrosine kinase inhibitors
87
Q

Sutent

  • Class
A

Sunitinib

  • Class: Tyrosine kinase inhibitors
88
Q

VANdetanib (Caprelsa)

  • Class
A

VANdetanib

  • Class: Tyrosine kinase inhibitors
89
Q

REGOrafenib (Stivarga)

  • Administration
  • Class
A

REGOrafenib

  • Take with food
  • Class: Tyrosine kinase inhibitors
90
Q

VorinOstat (Zolinza)

  • Class
  • Indication
  • Administration
  • Caution
A

VorinOstat

  • Class: Histone Deacetylase Inhibitor
  • I: lymphoma
  • Adm: 400 mg cap PO with FOOD
  • Caution: QT prolongation
91
Q

RomiDEPsin (Istodax)

  • Class
  • Indication
  • DF
A

RomiDEPsin

  • Class: Histone Deacetylase Inhibitor
  • I: cutaneous T-cell lymphoma
  • DF: IV
92
Q

Hydrea

  • Indication
A

Hydroxyurea

  • Indication: antineoplastic use, sickle cell anemia
93
Q

Thalomide

  • SEs
  • Special program
A

Thalidomide

SEs

  • Birth defect
  • Thrombo-embolitic events
  • Peripheral neuropathy

=> Require Thalidomide Education & Prescribing Safety (STEPS): dispensing right to authorized MDs or pharmaCIES
=> Pt must be on 2 forms of contraceptive

94
Q

Pomalidomide (Pomalyst)

  • Indication
  • Derivative of
  • Special Program:
A

Pomalidomide

  • I: mulitple myeloma
  • Derivative of thalidomide
  • Program: Women of reproductive potential must use 2 forms of contraception or continuously abstain from heterosexual sexual intercourse during and for 4 weeks after stopping treatment. Pomalidomide is only available through a restricted distribution program called Pomalyst Risk Evaluation and Mitigation Strategy (REMS)
95
Q

Chemo Man

96
Q

Erythropoetin/Darbepoetin

  • CI
  • Warning/Precaution
  • Monitoring Parameters
A

CI:
- Uncontrolled HTN

Warning/Precaution
- Thromboembolism events
- Tumor Progression
=> High Hgb: inc risk of MI, stroke, clot
=> Keep Hgb b/w 10-12g/dL
=> Once chemo stop, stop Epogen or Aranesp

Monitoring

  • BP, CBC w/ diff, platelet, Hgb
  • Sr Ferritin => start Fe if Start if saturation Correct Fe, B12, Folate prior to tx
97
Q

How long does the followings live?

  • Platelets
  • RBC
  • Granulocytes
A
  • Platelets: 10 days
  • RBC: 120 days
  • Granulocytes: 6-8H => neutropenia occurs w/in hrs of chemo.
98
Q

Tumor lysis syndrome

  • Results in:
  • Problems
A

Result in ARF, multiple organ failure, death

  • Hyperkalemia
  • Hyperuricemia
  • Hyperphosphatemia
  • Hypocalemia

Problems

  • Cardiac arrhythmia: hyperK = arrhythmia. HypoCa = QT int lengthening = V. arrhythmia
  • Electrolytes: transcellular shift of K
  • Hyperuricemia: give allopurinol & hydration to prevent uric acid crystal within collecting ducts = ARF
99
Q

Treatment of tumor lysis syndrome

A

Administer IV CaCl

  • Tx HyperK or HypoCa
  • Protect myocardium from arrhythmias
  • CaCl contains 3x Ca++ element (1g = 290mg) than Ca gluconate (1g = 90 mg).

Na Bicarbonate
- Shift K intracellular

Insulin (Novolin, Humulin) & dextrose
- Shift K intracellular

Kayexalate

  • Exchange Na for K and binds to K in gut => decr total body K.
  • OSA: PO 2-12H. Per rectal = longer osa
  • Give as 2nd stage of therapy to reduce total body K
  • SEs: constipation
  • Don’t give w/ sorbital = GI necrosis
100
Q

General Policy & Procedures of Fan/Blower

A

See Book page 5

101
Q

Disulfiram reaction

A
  • Procarbazine

- PacliTAXel

102
Q

Alterna Gel

  • Class
  • Indication
A

Aluminum hydroxide

  • Class: Phosphate binder
  • Indication: hyperphosphatemia
103
Q

PhosLow

  • Class
  • Indication
A

Calicium acetate

  • Class: Phosphate binder
  • Indication: hyperphosphatemia
104
Q

Fosrenol

  • Class
  • Indication
A

Lanthanum carbonate

  • Class: Phosphate binder
  • Indication: hyperphosphatemia
105
Q

Renagel

  • Class
  • Indication
A

Sevelamer

  • Class: Phosphate binder
  • Indication: hyperphosphatemia
106
Q

Velphoro

  • Class
  • Indication
A

Sucroferric oxyhydroxide

  • Class: Phosphate binder
  • Indication: hyperphosphatemia
107
Q

CaCl and Ca-gluconate

Which has more Ca

A

CaCl has more Ca

1gCaCl = 270mg Ca
1g CaG = 90 mg Ca

108
Q

Aloprim

A

Allopurinol

109
Q

Zyloprim

A

Allopurinol

110
Q

Elitek

A

Rasburicase

111
Q

Kayexalate

  • SEs
A

Sodium polystyrene sulfonate

  • SEs: constipiation
112
Q

Chemo induced neuropathy

  • Drugs
A

PPT

P = platinum drug
P = Plan alkaloids
T = Taxanes
113
Q

Valchlor

  • Storage
  • Form
  • Major SE:
A

Mechlorethamine

  • Storage: fridge
  • Form: topical gel
  • Major SEs: Fertility imp
114
Q

Voraxaze

  • Indicatio
A

Glucarpidase

  • Indication: MTX rescue med
115
Q

Vectibix

  • Form
  • Class
  • Indication
A

Panitumumab

  • Form: IV
  • Class: EGFR
  • Indication: Colorectal cancer
116
Q

Erbitux

  • Form
  • Class
A

Ceteximab

  • Class: EGFR
  • Form: IV
117
Q

Avastin

  • Mix with
  • Class
A

Bevacizumab

  • Mix with NS
  • Class: VEGF
118
Q

Beleodaq

  • Class
  • Indications
  • Form
A

Belinostat

  • Class: histone deacetylase inhibitor
  • Indication: lymphoma
  • Form: IV

12. Chemotherapy (6 decks)

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