Brain Tumours Flashcards
Stage IV Automatic
Glioblastoma multiforme
Fried egg tumour
Oligodendroglioma
Piloid hairy cell
Pilocystic Astrocytomas
Necrotic core
Glioblatsoma multiforme
Progress to Glioblastoma multiforme
Diffuse Astrocytoma
Rosenthal fibres and granular bodies
Pilocystic adenomas
Prominent brain tumour in children
Medulloblastoma
30% contain calcification
Oligodendroglioma
According to the WHO criteria a grade III tumour causes death within
5 years
According to the WHO criteria a grade IV tumour causes death within
6m - 1 Year
Does not infiltrate
Compression
Encapsulated
Meningioma
cerebellar signs, cranial hypertension
Medulloblastoma
Grade IV
Mutation of IDH1 in 80% of cases.
Diffuse Astrocytomas
Pallisades: build up of cells to fence off necrotic tissue
Glioblastoma Multiforme
Chemosensitive
Better prognosis than astrocytomas – resection is important
80% mutation of IDH1; 75% codeletion 1p19q; usually normal p53
Oligodendroglioma
= fried egg tumour