Brain Tumors Flashcards

1
Q

brain tumors are the leading cause of what in children under 20?

A

Solid tumor!

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2
Q

primary tumors MC in who, secondary tumors MC in who?

A

children

adults

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3
Q

common secondary forms of cancer that can mets to the brain?

A
breast
lung 
melanoma
lymphoma
renal cell 
thyroid
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4
Q

benign brain tumor cells do not contain what?

A

cancer cells

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5
Q

some major s/s?

A

HA usually worse at night

N/V, changes in speech, vision, hearing, balance, changes in mood, concentration, memory problems, SEIZURES, numbness or tingling

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6
Q

meningiomas may occur where? and arise from what cells?

A

intracrainally or within spinal cap

arachnoidal cap cells

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7
Q

where are meningoimas commonly found?

A

surface of the brain (skull base or convexity)

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8
Q

MC brain tumor?

A

astrocytoma (glioma)

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9
Q

grading of astrocytomas:

1:
2:
3:
4:

A

children, tx with surgery, juvenile pilocytic astrocytoma, occurs in cerebellum

low grade, adults

anaplastic astrocytoma or malignant astrocytoma

glioblastoma multiforme contain dead tissue within it

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10
Q

most pituitary adenomas are what?

A

benign (located in the anterior part of the gland)

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11
Q

microadenomas <1cc
macroadenomas > 1cc

this is important why?

A

pituitary fossa is 1cc

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12
Q

anterior pituitary adenomas effect what hormones?

A
FSH
LH
ACTH
TSH
GH
ILF-1
Prolactin
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13
Q

posterior pituitary adenomas effect what hormones?

A

ADH

Oxytocin

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14
Q

medulloblastoma arises from what cells where?

A

medulobastic cells in cerebellum

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15
Q

acoustic neuroma:

what kind of tumor?
what cells?
seen with what?

A

bening tumor of the Schwann cell of CN VIII

neurofibromatosis

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16
Q

some txs of tumors?

A

surgery
focused beam radiation (Gamma knife)

transsphenoidal surgery for pituitary adenomas

chemo

17
Q

some s/s of pseudotumor cerebri?

A
obese female of childbearing age 
transient visual obscurations
intracranial noises 
photophobia
retrobulbar pain 
diplopia 
sustained vision loss
18
Q

etiologies of pseudotumor cerebri

A
venous thrombosis 
otitis media
obesity
addisons 
head injury 
pregnancy 
cystic fibrosis 
iron def anemia
steriod withdrawl
hypoparathyroidism 
meds (tetracycline, vit A, cipro, pehnytoin, ASA, amphotericin B)
19
Q

on PE what do we want to look for for pseudotumor cerebri?

A

papilledema
visual field loss
6th nerve palsy

20
Q

dx of pseudotumor cerebri?

A

LP >250mmH2O is abnormal

21
Q

tx of pseudotumor cerebri?

A

weight loss/low sodium
Acetazolamide
Topiramate