Brain- Lower Flashcards
What are the major parts of the brain?
Brain stem
Cerebellum
Diencephalon
Cerebrum
What does the brain stem consist of?
Medulla oblongata
Pons
Midbrain
What is posterior to the brain stem?
Cerebellum
Little brain
What is superior to the brain stem?
Diencephalon
What is the diencephalon comprised of?
Thalamus
Hypothalamus
What is the largest part of your brain?
Cerebrum
Continuous with spinal meninges
Cranial meninges
What is the basic structure of the meninges?
Dura mater (outer) Arachnoid mater (middle) Pia mater (inner)
hat are the two layers of the cranial dura mater?
External periosteum layer
Internal meninges layer
What does the BBB protect the brain cells from?
Harmful substances and pathogens by preventing them from entering the brain
What are the places that lack the BBB?
Pineal gland
Pituitary gland
Hypothalamus
- They hall secrete hormones directly into the bloodstream
What can break down or disrupt the BBB?
Trauma
Certain toxins
Inflammation
What is the BBB formed by?
Combination of tight junctions of the endothelial cells of brain capillaries and astrocyte foot processes
How do some water soluble substances (such as glucose) cross the BBB
Active transport
What substances cross the BBB very slowly
Creatinine
Urea
Most ions
What substances do not cross the BBB?
Proteins
Most antibiotic drugs
What substances cross easily?
Oxygen
CO2
Alcohol
Most anesthetic agents
What makes the BBB more leaky?
High concentration of sugar mannitol produces high osmotic pressure that causes endothelial cells of capillaries to shrink, which opens gaps between their tight junctions
What does CSF do?
- Protect the brain and spinal cord against chemical and physical injuries
- Carries oxygen, glucose, and other needed chemicals from the blood to neurons and neuroglia
- Continuously circulates through cavities in the brain and spinal cord, and around brain and spinal cord in subarachnoid space (between arachnoid mater and pia mater)
What is the mechanical protection of the CSF?
Shock-absorbing medium that protects tissues of the brain and spinal cord
- causes it to float in cranial cavity
What is the chemical protection of the CSF?
Providing optimal ionic composition chemical environment for accurate neuronal signaling
What is the circulation that contributes to the homeostasis of CSF?
Acting as a medium for exchange of nutrients and waste products between the blood and nervous tissue
What is CSF produced by?
Choroid plexuses in walls of ventricles
What are networks of capillaries covered by ependymal cells that form CSF from blood plasma by filtration (some secretion)
Choroid plexuses
CSF flows into their ventricle through two small openings called?
Interventricular foramina
The roof of the third ventricle produces more?
CSF
How does the CSF reach the fourth ventricle/.
Flows through cerebral aqueduct
Does the choroid plexus in the fourth ventricle produce more CSF?
Yes
From the fourth ventricle, the CSF enters the
Subarachnoid spaces
How does the CSF enter the subarachnoid space?
Through three openings
A median aperture
Two lateral apertures
What is continuous with the subarachnoid spaces?
The spinal cord
What is CSF reabsorbed into blood through?
Arachnoid villi
- project the CSF into the circulatory spaces
How is CSF reabsorbed?
As fast as it is formed, meaning the pressure remains constant
A condition in which excess cerebrospinal fluid builds up in the brain
Hydrocephalus
How is hydrocephalus treated?
Place a shunt system with diverts the flow of CSF to another area of the body