brain disorders Flashcards
review: what makes up the nervous system
1) central nervous system: composed of brain + spinal cord
2) peripheral nervous system: composed of 12 pairs of cranial nerves, 31 pairs of spinal nerves, and autonomic nervous system
- somatic: voluntary movements
- autonomic: involuntary movements (sympathetic/parasympathetic)
sympathetic nervous system
“fight/flight”
- dilated pupils
- increase HR/BP
- increased rate of breathing
- decreased peristaltic movements of digestive tube
- thick viscid saliva secretion
- increased conversion liver glycogen to glucose
- relaxed urinary bladder muscles
- increased secretion of sweat
- secretion of epinephrine and norepinephrine
parasympathetic nervous system
“rest/digest”
- constricted pupils
- decreased HR/BP
- decreased rate of breathing
- increased peristaltic movements of digestive tube
- thin, watery saliva secretion
- contracted urinary bladder muscles
- dilated blood vessels
review: neurotransmitters acetylcholine
- major transmitter of the parasympathetic nervous system
- source: many areas of the brain, autonomic nervous system
- action: EXCITATORY, parasympathetic effects sometimes inhibitory (stimulation of heart by vagal nerves)
review: neurotransmitters serotonin
- source: brain stem, hypothalamus, dorsal horn of spinal cord
- action: INHIBITORY, controls mood and sleep, inhibits PAIN PATHWAYS
review: neurotransmitters dopamine
- source: substantia nigra and basal ganglia
- action: usually INHIBITORY, affects behavior (attention/emotions) and fine movement
review: neurotransmitters norephinephrine
- major transmitter of the sympathetic nervous system
- source: brain stem, hypothalamus, postganglionic neurons of the sympathetic nervous system
- action: usually EXCITATORY, affects mood and overall activity
review: gamma aminobutyric acid (GABA)
- source: spinal cord, cerebellum, basal ganglia, some cortical areas
- action: INHIBITORY
review: endorphin
- source: nerve terminals in spine, brain stem, thalamus, hypothalamus, pituitary gland
- action: EXCITATORY, pleasurable sensation, inhibits PAIN transmissions
excitatory
excites (activates) activity of target cell
inhibitory
inhibits (stops) activity of target cell
meninges
fibrous connective tissue that cover brain/spinal cord provides protection, support, and nourishment
- 3 layers: dura mater, subarachnoid, arachnoid
dura mater
tough, inelastic, fibrous, gray
- “top mother”
subarachnoid mater
“weblike, cushions, delicate”
- arachnoid villi absorbs CSF -> venous system
pia mater
“inner most layer of the brain, delicate”
- thin, goes into different folds of the brain
- transparent
frontal lobe
largest lobe, front of brain
function:
- concentration
- abstract thought
- information storage or memory
- motor function
- affect
- judgement
- personality
- inhibitions
parietal lobe
sensory lobe, posterior to frontal
function:
- analyzes sensory information and relays interpretation of this information to other cortical areas
- essential to person’s awareness of body position and orientation
- taste, touch, pressure, body awareness
temporal lobe
inferior to parietal and frontal lobe
- auditory receptive areas, memory of sound and understanding language and music
- facial recognition
occipital lobe
back of head
- visual interpretation, memory
cerebellum
coordination, positional (postural) sense
changes in nervous system related to aging (neuro changes associated with aging) (7)
1) slower processing time (provide sufficient time for patient to respond to questions or instructions)
2) recent memory loss (reinforce teaching by repetition, written language, employing memory aids like electronic alarms or applications for devices that provide recurrent alerts)
3) decreased sensory perception of touch (remind patient to look where they are positionally)
4) change in perception of pain (assess pain and monitor for health problems)
5) change in sleep patterns (assess sleep habits and preferences and provide usual routine)
6) altered balance and/or decreased coordination (move slowly when changing positions, assess needs for mobility aids)
7) increased risk for infection (monitor carefully for infection s/sx)
brain disorder assessment PE
1) compare each assessment with pt. baseline, R vs L, UE vs. LE
2) evaluate mental status, cranial nerves, mobility, motor function, sensation, reflexes and cerebellar function
- brainstem, thalamus, cortex lesions -> loss of sensation on contralateral sides of the body (opp)
- cerebellar lesions -> sensory deficits on same side of the body
3) assess memory
- long term, recall/recent, immediate memory
- loss of memory, especially recent memory, tends to be an early sign neurologic problems (dementia)
decorticate
damage to hemispheres (higher functioning)
- flexed hands
- adducted arms
- flexed elbows
- internally rotated legs
- plantar flexed
decerebrate
damage to brain stem
- adducted arms
- extended elbows
- pronated forearm
- flexed hands
- plantar flexed
Romberg test
close eyes and balance, can be standing/sitting
- positive: loss of balance (abnormal)
- negative: no loss of balance (normal)
babinski test
- stroke lateral aspect of sole, patient toes will contract and draw together
- CNS disorder
- if toes fan out and draw back (adult) -> abnormal
- if toes fan out and draw back (newborn) -> normal
diagnostic evaluation labs
1) labs: glucose, cmp, cbc, abg, blood cultures, toxins, lumbar puncture (CSF)
- “spinal tap”
- needle is subarachnoid space to draw CSF -> lab (trauma at site, bit will be come more clear as continue to draw up)
- meds can be given through spinal canal
- tense/nervous: might artificially change pressure reading
- complications: post lumbar puncture headache, infection, nerve damage
normal CSF values
diagnostic evaluation imaging
- XRAY
- cerebral angiography (arteriography)
- ultrasound
- computed tomography (CT)
- magnetic resonance imaging/angiogram (MRI/MRA)
- positive emission tomography (PET)
- electroencephalography (EEG)
altered level of consciousness
- present when patient is not oriented, does not follow commands, or needs persistent stimuli to achieve a state of alertness
- most important indicator of the patient’s condition
- LOC is gauged on a continuum, with normal state of alertness and full cognition (consciousness) on one end and coma on other end
- initial alterations in LOC may be reflected by subtle behavioral changes, such as restlessness or increased anxiety
stages of altered LOC
1) coma
2) akinetic mutism: no voluntary movements
3) persistent vegetative state
4) minimally conscious state
5) locked in syndrome: lesions affects pons -> paralysis, doesn’t speak, have vertical eye movement and lid elevation
nursing assessment for altered LOC (12)
1) level of responsiveness or consciousness (eye opening, verbal and motor responses, pupils)
2) pattern of respiration (RR, cheyne-stroke respiration, hyperventilation, ataxic respiration with irregularity in depth/rate)
3) eyes/pupils (size, equality, reaction to light) (PERLA)
4) eye movements (side to side)
5) corneal reflex (brisk response when touched with clean cotton)
6) facial symmetry (asymmetry - sagging, decrease in wrinkles)
7) swallowing reflex (drooling vs. spontaneous swallowing)
8) neck (stiff neck)
9) respond of extremity to noxious stimuli (firm pressure on a joint of UE/LE)
10) deep tendon reflexes (tap patellar and biceps tendon)
11) pathologic reflexes (firm pressure w/ blunt object on sole of foot, moving along lateral margin and crossing ball of foot)
12) abnormal posture (observation for posturing, flaccidity with absence of motor response, decorticate or decerebrate posturing)
altered LOC nursing interventions
- maintain airway
- aspiration precautions
- protect the patient
- maintain fluid balance and nutritional needs
- provide oral hygiene
- maintaining skin and joint integrity
- preserve corneal integrity
- maintain body temperature
- promoting urinary elimination and bowel function
increased intracranial pressure (what, cause, example)
- rise in pressure inside the skull that can result from or cause brain injury
- causes: decreases cerebral perfusion, stimulates further swelling (edema), and may shift brain tissue, resulting in herniation
- monro Kellie hypothesis
what is monro Kellie hypothesis
pressure volume relationship that aims to keep. dynamic equilibrium among the essential non-compressible components inside rigid compartment of the skull
- blood
- CSF
- brain matter
changes in ICP are closely linked with
cerebral perfusion pressure (CPP)
cerebral perfusion pressure
- pressure gradient over which the brain is perfused
- through auto regulation, normal cerebral vasculature maintains an adequate cerebral blood flow with a wide range (50-150 mmHg) of mean arterial blood pressure (MAP) -> perfusion
- maintenance of CPP above 70 mmHg is generally accepted as an expected outcome of therapy
- rise in MAP -> elevated ICP
- decrease in MAP -> hypoperfusion
- equation: MAP - ICP = CPP
s/sx increased intracranial pressure (9)
- decreased LOC
- behavior changes (restlessness, irritability, confusion)
- headache
- N/V
- changes in speech (aphasia, slurred speech)
- seizures
- changes in sensorimotor status (pupillary changes, cranial nerve dysfunction, ataxia)
- Cushing’s triad (increased SBP w/ widened pulse pressure, bradypnea, bradycardia)
- abnormal posturing
complications of increased intracranial pressure
1) brainstem herniation
2) diabetes insipidus (DI)
3) syndrome of inappropriate antidiuretic hormone (SIADH)
brainstorm herniation
shifting of brain tissue from an area of high pressure to an area of lower pressure
- herniated tissue exerts pressure on the brain area into which it has shifted, which interferes with the blood supply in that area -> cessation of cerebral blood flow results in cerebral ischemia, infarction, and brain death