Brain Development Flashcards

1
Q

When does the anterior neuropore close? posterior?

A

day 25 and 28

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2
Q

What transition must NC cells undergo?

A

epithelial to mesenchymal

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3
Q

What do dorsal NC cells become? Ventral? Other things?

A

melanocytes and skin follicles

ganglia and neurons

neurons of head and face as well

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4
Q

What day do the three primary brain vesicles form? from what?

A

day 28

expansions of the cranial neural tube

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5
Q

What three primary brain vesicles form as expansions from the cranial neural tube? what will they become?

A

prosencephalon -> forebrain
mesencephalon -> midbrain
rhombencephalon -> hindbrain

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6
Q

The prosencephalon divides into: ________ and _______ on day ____.

A

telecephalon and diencephalon

32

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7
Q

The Rhombencephalon divides into: ________ and _______ on day ____.

A

metencephalon

myelencephalon

32

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8
Q

The metencephalon is the future site of what two structures?

A

pons and cerebellum

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9
Q

What does the neural canal expand into in each vesicle?

A

a primitive ventricle

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10
Q

What does the primitive ventricle become in the rhombencephalon, mesencephalon, diencephalon, and telencephalon?

A

rhomb: 4th ventricle
mes: aqueduct of Sylvius
di: becomes 3rd ventricle
tel: lateral ventricles

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11
Q

How many places does the brain tube fold? When?

A

3 places

4-8weeks

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12
Q

What are the folds in the brain tube?

A

mesencephalic flexure within midbrain

cervical flexure between the myelencephalon and spinal cord

pontine flexure within the metencephalon

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13
Q

What does the rhombencephalon/hindbrain become?

A

brain stem

myelencephalon -> medulla oblongata (heart beat, breathing, swallowing)

metencephalon -> pons, cerebellum (coordination center for posture and movement)

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14
Q

Cerebellum begins forming around what time? until?

A

6th week -> birth

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15
Q

What can be found in the midbrain?

A

massive tracts of white matter than connect fore and hindbrains

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16
Q

What does the telencephalon become? What happens in later 3rd tri?

A

cerebral hemisphere

folding to form lobes and gyri

17
Q

What % of births have a CNS malformation?

A

1%