Brain Flashcards

1
Q

What is an Arnold Chiari Malformation?

A

A condition affecting the brain. Consists of a downward displacement of the cerebellar tonsils through the foramen magnum causing non-communicating hydrocephalus as a result of obstruction of CSF outflow

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2
Q

Where do meningioma arise from?

A

The arachnoid “cap” cells of the arachnoid villi in the meninges

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3
Q

What structures do meningioma’s lie between

A

Falx and cerebral hemisphere

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4
Q

What are of the body is represented on the medial side of the motor area?

A

Lower limbs (feet nearest the midline)

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5
Q

What area is located in the pre-central gyrus of the brain?

A

The primary motor cortex

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6
Q

Which layer of meninges is a meningioma attached to?

A

The dura

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7
Q

What type of contrast is used for an MRI brain

A

Gadolinium

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8
Q

What is meant by ring enhancement?

A

An abnormal radiological sign on MRI or CT using radiocontrast.
On the image there is an area of increased density surrounded by a bright rim from concentration of the enhancing contrast dye
This enhancement may represent breakdown of the blood brain barrier and the development of an inflammatory capsule

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9
Q

What are the differential diagnoses for ring enhancement?

A

Metastasis
Abscess
Glioblastoma
Infarct (subacute phase)
Contusion
Demyelinating disease
Radiation necrosis or resolving haematoma

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10
Q

What is the aggressive form of glioma

A

Glioblastoma multiforme

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11
Q

How does CSF circulate

A

Produced by the choroid plexuses within the lateral ventricles > Interventricular foramen (Foramen of Monroe) > Third ventricle > aqueduct of sylvius > fourth ventricle > Foramen of Luschkam and Magendie > Subarachnoid space > arachnoid villi > superior sagittal sinus

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12
Q

What is the circle of Willis?

A

An anastomosis between the internal carotid arterties and vertebral arteries on the inferior surface of the brain

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13
Q

What is the circle of Willis formed from?

A

Anterior communicating artery
Anterior cerebral artery
Internal carotid artery
Posterior communicating artery
Posterior cerebral arteries and the termination of the basilar artery

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14
Q

What are the features of the vertebral arteries?

A

Enter the cranial canal via the foramen magnum
Lie in the subarachnoid space
Ascend on anterior surface of the medulla oblongata
Unite to form the basilar artery at the base of the pons

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15
Q

What are the branches of the vertebral arteries?

A

Posterior spinal artery
Anterior spinal artery
Posterior inferior cerebellar artery

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16
Q

What are the branches of the basilar artery?

A

Anterior inferior cerebellar artery
Labyrinthine artery
Pontine artery
Superior cerebellar artery
Posterior cerebellar artery

17
Q

What are the branches of the internal carotid artery?

A

Posterior communicating artery
Anterior cerebral antery
Middle cerebral artery
Anterior choroid artery

18
Q

What is the entry of the vertebral artery into the skull?

A

Vertebral artery enters the skull through the foramen magnum
It crosses transversely across the posterior arch of the atlas

19
Q

What is the course of the vertebral artery?

A

Inside the skull, the 2 vertebral arteries pass upwards, forwards and medially in the subarachnoid space to reach the anterior aspect of the medulla oblongata, then they unite together at the lower border of the pons to form the basilar artery

20
Q

What do the Vertebral and basilar arteries supply within the brain?

A

The vertebrobasilar artery system supplies the medulla, cerebellum, pons, midbrain, thalamus and occipital cortex

21
Q

Which vein drains the dangerous area of the face?

A

Inferior ophthalmic vein

22
Q

Where does the ICA enter the skull and what is it’s course?

A

Enters the skull via the carotid canal in the petrous part of the temporal bone

23
Q

What branch is given off the ICA before the anterior and middle cerebral arteries?

A

Ophthalmic artery

24
Q

What condition does a berry aneurysm lead to?

A

Subarachnoid haemorrhage

25
Q

What are the signs of an MCA infarct?

A

Hemiplegia of the lower 1/2 of the contralateral face
Hemiplegia of the upper and lower extremities
Aphasia if in the dominant hemisphere

26
Q

What is the anterior attachment of tentorium cerebelli?

A

Superior angle of the petrous part of temporal bone

27
Q

Which blood vessel supplies the inner table of the temporal bone?

A

Middle meningeal artery

28
Q

If there is a tumour in the precentral gyrus which bone should be penetrated to get to the tumour?

A

Parietal bone

29
Q

Relationship between ICP and oculomotor nerve?

A

An increase in ICP leading to a oculomotor nerve palsy which leads to a dilated pupil

30
Q

What are false localising signs?

A

Neurological signs which reflect dysfunction distant or remote from the expected anatomical locus of pathology. They occur in two major contexts - as a consequence of raised ICP or with spinal lesions

31
Q

Which muscles are supplied by the oculomotor nerve?

A

Levator palpebrae superioris
Superior rectus
Inferior rectus
Medial rectus
Sympathetic fibres to Muller’s muscle
Inferior oblique
Sphincter pupillae

32
Q

Paralysis of the oculomotor nerve leads to

A

THe eye being displaced downwards and outwards

Outward because the lateral rectus maintains muscle tone in comparison to the paralyed medial rectus as it is supplied by CN VI

Downwards because the superior oblique is un-anatgonised by the paralysed superior rectus, inferior rectus and inferior oblique

They will also have ptosis and mydriasis

33
Q

What is the structure on which the oculomotor nerve is pressed against?

A

Petrous part of the temporal bone, attached border of the tentorium cerebelli