Brachial Plexus Injuries & Reconstruction Flashcards

1
Q

Where do the roots, truncks, cords, divisions and terminal branches lie and what are their contributions

A
  • 5 Roots - C5-T1 (C8 and T1 exit from above named formina)
    • located betwene anterior and middle scalene
    • prefixed C4
    • post fixed T2
  • 3 Truncks - Upper (C5-C6), Middle (C7), Lower (C8-T1)
    • located in posterior triangle
  • 6 Divisions - Anterior and Posterior division of each
    • located posterior to clavicle
  • 3 Cords (Lateral, Medial, Posterior) in relation to axillary artery
    • located posterior to pectoralis minor
  • 5 Terminal branches (Rad, Ax, Uln, Med, MSC)
    • located in limb
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2
Q

CORDS

what forms and what is formed by each cord

A
  • LATERAL CORD
    • made up of C5-7 (anterior division of upper and middle trunks)
    • forms Lateral pectoral (ant division upper and middle T)
    • forms MSC (anterior division of upper and middle T)
    • forms lateral contributing branch of median nerve => contributes to sensation
  • MEDIAL CORD
    • made up of C5-T1 (anterior division of Lower trunk + gets lateral contributing branch to median nerve)
    • forms medial pectoral nerve, MABC, MBC
    • forms medial contributing branchof median nerve => contributes to intrinsics fx
  • POSTERIOR CORD
    • made up of C5-T1 (posterior division of all trunks)
    • forms upper, lower subscapular n and Td
    • forms Radia and Axilary branches
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3
Q

What nerves arises proximal to the cords on the brachial plexus?

A
  • Dorsal scapular nerve (C5 root)
  • Phernic nerve (C3,4,5 roots)
  • Long thoracic nerve (C5,6,7 roots)
  • Suprascapular nerve (upper trunk = C5,6)???
  • Lateral pectoral nerve (upper ttrunk anterior div = C5,6)???
  • Subclavius (upper trunk C5,6)
  • Paraspinal muscle nerves (longus colli, scalene muscles C5,6,7,8)
  • 1st intercostal (T1 root)
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4
Q

What is the incidence of OBPP

A

1-2/1000

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5
Q

How do you classify BP injuries

A

Pathology

  • root avulsion
  • nerve rupture
  • NIC

Location

  • preganglionic (~root avulsion)
  • postganglionic( ~nerve rupture)
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6
Q

What is important points on Hx and PE for BP injury assessment

A

Hx

  • mechanism, arm position when injured
  • associated injuries (spine/head/limbs/chest)
  • weakness/paresthesia
  • improvement with time (delayed assessment)
  • LOC/lifethreatening injuries (acute assessment)

PE

  • ABC, general exam if acute
  • peripheral pulse
  • BP exam - according to MRC grading
    • root avulsion
      • horners (C8,T1 avulsion or traction near)
      • head deviated away from injured side (weak paraspinals)
      • winging scapula and difficulty raising arm above horixontal ( weak serratus ant)
      • winging scapula and cannot be drawn close to vertebral column (weak rhomboids/levator scap)
      • subluxed humerus + inability to lift above horizontal (Supraspinatus)
    • tally functional and non-functional
  • BP exam sensation
    • light touch, 2PD static dynamic, vibration, joint position
    • root avulsion
      • painful limb
      • intact histamine response in anesthestic arm
      • intact SSEP in anesthetic arm
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7
Q

Spot diagnosis

Spontaneous recovery following diffuse BP injury with weak/slowly recovery arm abduction/external rotation

A

compression of SSN in Scapular Notch

May require release

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8
Q

What nerve injury would you suspect with posterior shoulder dislocation

A

axillary nerve rupture

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9
Q

Contrast findings for preganglionic vs postganglionic BP injuries

A
  • On inspection
    • flail arm for both
    • head direcetd away from injury in preGG
    • winging scapula preGG
    • horners preGG
  • On palpation and muscle testing
    • paralysis of limb for both
    • paralysis of diaphragm, serratus, rhomboids preGG
  • On palpation and sensory testing
    • paresthesia in both
    • intact histamine response in preGG
    • deafferentiation PAIN in preGG
    • Tinels ABSENT preGG
  • On investigation
    • pseudomeningocele in myelogram preGG
    • NCS: absent motor EP for both
      • sensory EP in postGG
      • ABSENT SENSORY EP in preGG
    • EMG: denervation limb for both
      • paraspinal denervation preGG
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10
Q

What investigations would you order for BP assessment, when and why?

A
  • On initial assessment
    • Chest X-ray - Fractured cpsine, clavicle, ribs, humerus/shoulder girdle
    • Ins/Exp CXR - diaphragm injury (or U/S)
    • Arteriogram
      • penetrating injury
      • normal initial exam then abnormal exam (R/O expanding hematoma)
  • 4weeks post trauma
    • CT/Myelogram
      • to assess root avulsion - traumatic pseudomeningocele correlates w avulsion
  • >3wks post trauma
    • ElectoDiagnostic studies:
    • EMG
      • identify denervation injury
        • fibrillation ant rest
        • reduced MUP with voluntary effort
    • NCS
      • identify interruptions in nerve continuity and level of injury
      • postive SNAP in paresthetic arm = pathognomoni for root avulsion
        *
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11
Q

What are treatment options for BP injuries

A
  • Non-operative
    • PT to maintain ROM/joint mobility
    • treat fractures with immobilization
  • Operative management
    • neurolysis
    • autogenous nerve grating
    • nerve transfers
    • secondary procedures (NT, TT, osteotomies)
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12
Q

What are principles for deciding on operative management for BP injuries

A
  • Outcomes are better with spontaneous recovery compared to operative Tx
  • Patients who require operative Tx have better outcomes if done earlier
  • Patients with SUnderland 4-5 injuries benefit from operative intervention, not sunderland 1-2
  • Patients w sunderland 3 recvere with some partial deficits with can be corrected w 2’ procedures
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13
Q

what are indications for operative intervention for BP injury

A
  • Penetrating injury with BP deficits
  • clear indication of injury to Roots
  • lack of functional recovery after period of observation
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14
Q

What are contraindications to primary reconstruction of BP injury

A

ABSOLUTE

  • Medically unfit
  • demonstrates spontaneous recovery

RELATIVE

  • comorbidities, TBI, SCI
  • over 1yr since injury in adults
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15
Q

How do you prioritize reconstruction of total branchial pleoxpathy

A

Based on principles of

  • function significance
  • likelihood of regained fx w operation
  • degree of difficulty achieving function w 2’ surgery

Order of reconstruction

  • Elbow Flexion
  • Shoulder stabilization (abdunction,external rotation, flexion)
  • Sensation to C5,6 (lateral cord)
  • Wrist and finger flexion (with consideration of Triceps extension if planning FFMT for elbow)
  • Wrist and finger extension
  • Intrinsics
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16
Q

How do you provide shoulder stability and goals of recon

A
  • stabilize shoulder to prevent pain of subluxation and for platform to properly tuilize elbow flexion
  • reinnervate Supraspinatus (abduction) and Infraspinatus (external rotation) with SA to SSN
  • reinnervate Deltoid (abduction/flexion) via triceps br to Axllary
17
Q

How do you manage Open BP injuries?

A

OPEN AND EXPLORE

  • Sharp laceration
    • => 1’ epineurial repair
    • => vascular repair with vein grafts in conjunction b/w vascualr and plastic Sx
  • Crush/nerve loss
    • => identify, tag and map out injury
    • return in 3wks (following completion of any WD likely to occur) for grafting as required
  • Gunshot
    • expected sunderland 1,2 and 3 injuries
    • most improve in 3mths
    • EARLY EXPLORATION ONLY if associated vascular injury
    • observe 4 mths - if no evidence on PE or EDS of improvement, explore
18
Q

What is the difference between SS Evoked potential/ Motor Evoked potential and Nerve Actional potential?

A
  • EP determine continuity across Scord and peripheral nerve
  • AP determine contuity across nerve segment
19
Q

What are intraoperative adjuncts unsed for BP recon and why?

A
  • AP and EP to determine continutiy across nerve segment (AP) and continuity form Scord to peripheral nerve (EP)
  • Biopsies/frozen sections to determine healthy axon ends for grafting, and distinguishing ganglions cells (avulsion injury) and scar tissue
    *
20
Q

What histochemical stians are used on proximal stump to distinguish sensory from motor?

A
  • Sensory: Carbonic anhydrase
  • Motor: Thiocoline (cholinesterase enzyme)
  • Motor: Choline Acetyl trasnferase activity

**can only stain distal stump up to 5 days post injury

21
Q

What are options for surgical management of BP injuries

A
  • 1’ neurorrhaphy
    • Indicated: sharp trasnsection (rare)
    • Indicated: nerve rupture and no tension
  • neurolysis
    • Indicated - Neuroma with intact NAP
    • external (epineurium fro surrounding)
    • internal (perineural - along fascicles
  • Nerve grafting
    • Indicated - Neuroma with no NAP
    • NIC w no NAP=>excision and grafting
    • INdicated: Nerve rupture
  • Nerve transfer
    • Indicated - root avulsion
22
Q

What are options for autogenous nerve grafts

A
  • Non-vascularized
    • Sural (3-40cm)
    • Supraclvicula rn from cervical plexus
    • MABC, LABC, MBC
    • DSRn
  • Vascularized
    • ulnar n
    • radial n
    • sural n
23
Q

What are indications for nerve transfers

A
  • Irreparable PreGG
  • Select PostGG
    • insufficient proximal stump
    • prohibitively long distance for reinnervation
    • undefined level of nerve injury
    • prohibitively difficult surgery in zone of injury
    • BP neuritis
  • Reinnervation of FFMT
24
Q

What are 3 principles of nerve trasnfer

A
  • select donor nerve close to end organ
  • select expandable donor nerve
  • select donot nerve w synergy/easy to relearn
25
Q

Shoulder stabilization:

  • SAN to SSN and Medial Triceps to Axillary

Why is posterior approach favored over anterior approach

A
  • preserve proximal fibers of SAN to upper muscle fibers of Trapezius and divide DONOR as DISTAL as possible
  • release scapular notch
  • dissect Axillary N proximally to include fibers and reinnervate Teres minor (external rotation) and divide RECIPIENT as PROXIMAL as possible
  • Get donor trasnferring nerve as close to end organ as possible
26
Q

What are the anatomic landmarks for SAN

A

40% the distance from midline to acromion, along superior border of scapula

Nerve runs on undersurface of trapezius

27
Q

What is the anaotmic landmark of the SSN

A

50% the distance between the acromion and the superomedial edge of the scapula

At this point, the SSN is in Scapular notch

28
Q

What is the oberlin trasnfer and the double fascicular trasnfer

A
  • Oberlin trasnfer: nerve trasnfer of ulnar nerve motor fascicles from FCU to biceps branch for elbow function (MSC origin)
    • ulnar nerve br is carefully selected by stimulation to ensure donot flexes wrist and is not involved in intrinsics
  • Double Fascicular trasnfer = Oberlin’s trasnfer + median nerve fascicle from FCR/PL transferred to Brachialis
29
Q

Whata re the arguments for and against contralat C7 donor for panplexopathy

A
  • C7 nerve trasnfer using vascularized ulnar n to reinnervation shoulder, elbow, hand contralaterally
  • Argument for:
    • large donor with many axons avialable for reinnervation of many targets
    • no permanent functional deficit in donor arm (get transient motor weakness and paresthesia in C7 dermatome which resolves in 6mths
  • Argument against:
    • risk neuropathic pain, permant sensory/motor deficit
    • difficult to activate recipient without activating donor limb
    • long distance for reinnervation
30
Q

What nerve trasnfers are performed for restoration of sensation?

A

Depends on whether partial (1stage) or complete plexopathy (need 2stages)

  • Partial plexopathy - use web space donor of non-critical to restore critical.
    • eg. upper trunk plexopathy => use ulnar nerve donor 4th Webspace CDN to trasnfer to 1st webspce for median nerve
  • Complete plexopathy - 2 stages - restore one nerve proximally an once evidence of reinnervation , use reinnervated nerve non critical sensosry br for critical nerve restoration
    • eg. total plexopathy => restor eulnar n with IC trasnfer then once reinnervtion present, do trasnfer listed above (4thWS to 1stWS)
31
Q

What are options for secondary reconstruction for BP injury

A
  • TT
  • FFMT
  • arthrodesis
  • pedicled musle trasnfers
32
Q

What are options for 2’ recon of shoulder abduction/external rotation/flexion?

A
  • Trapezius to humerus
  • Episco procedure - Lat dorsi and teres major trasnfer posterolateral on humerus
  • Biceps and triceps long head advanced to acromion
  • Posterior deltoid rotated anteriorly

If not possible, then arthrodesis

33
Q

What are options for secondary recon of elbow flexion? (all indicated for upper trunk/MSC injury with delayed presentation or no evidence of elbow function recovery)

A
  • Steindler modified flexorplasty
    • medial epicondyle w flexor pronator mass transfered to anterolat humerus
  • Triceps to biceps
    • medial triceps to biceps tendon
  • Pedicled muscle trasnfer
    • Lat dorsi - bipolar => both origin and insertion are trasnferred. HUmeral origin to Coracoid, Tubed insertion of lat to biceps tendon
    • Pec major - bipolar => origin on humerus trasnfered ot acromion, insertions with rectus abdo fascia sutured to biceps
  • FFMT
    • gracilis
34
Q

How do you manage pain syndromes associated with BP injury

A

50% without root avulsions, 80% with root avulsions

  • good response to nerve repair
    • neurolysis, nerve grafting, neuroma excision and grafting
  • PT
  • pain specialist
  • TENS
35
Q

How do you classify obstetrical BP injuries

A
  • Upper plexus palsy C5,6 +/- C7
    • most common
    • shoulder adducted, internally rotated, wrist & fingers flexed, pronated
  • Lower plexus palsy C8 T1
    • rare
    • hand atrophy and weak wrist flexors +/- horners
36
Q

What are indications surgical intervention in OBPP

A
  • EARLY at 1-2months
    • Total plexopathy with Horners and NO improvement in 1st month - operate at 2mo
    • they will demonstrate no sponaneous recovery
    • if evidence of some recovery at 1mth , continue to observe until 3mths
  • At 3mths
    • Surgery if no elbow flexion Plus No elbow/wrist/finger extension
    • if score >3.5 (motion >1/2 gravity eliminated) continue to observe
    • if some biceps function, continue to observe
  • At 9 months
    • Surgery if elbow flexion< 6 (= less than half of normal motion) -. Cookie test - elbow held adducted and child encouraged to eat cookie with less than 45’ neck flexion
  • Surgery recommended at any time if reocvery stops
37
Q
A