Boyer Stuff Flashcards
Cell type
Acute or chronic?
Job?
Special contents
Notes
Nuetrophils
Acute
Phage and damage bugs
Lysosomes, acid hydrolases, ROS
Monocytes/Macropahges
Chronic
Phage, reg inflammation, reg coagulation. Start repair
Lysozymes, cytokines, elcosanoids, ROS,cations, GFs
Some sentinel cells
Lymphocytes
Chronic
Secrete Ab, adaptive immunity
Contents vary between types
Some sentinel cells
Eosinophils
Chronic
Phage, Type 1 hypersensitivity, attack parasites
Lysosomal granule enz, ROS, prostaglandins
Some sentinel cells
Mast cells/Basophils
Neither/both?
Type 1 hypersensitivity
Preformed histamine, serotonin, heparin, serine. Prostaglandins, luekotrienes, eosinphils, chemokines.
Some sentinel cells
Platelet
Neither
Thrombosis, reg permeability of vessels
Delta: Serotonin, Ca, phosphate, ATP. Alpha: Fibrinogen. Lysosomes: acid hydrolases
Vasodilators
histamine, PG, PAF, NO
Increase Vascular Permeability
histamine, serotonin, LT, PAF, substance P
WBC chemotaxis
C3a, C5a, LT, PAF, IL, TNF, chemokines, cytoplasmic granule content, thrombin
Tissue or Microbe damage
ROS, cytoplasmic granules, MAC
Pain
Substance P, bradykinin, PGs
Fever
PGs, IL, TNF