Bowel, Bladder, and Sexuality in Neurologic Disease

Question 1

Filling: involves relaxation of detrusor muscle, and contraction of sphincters. Accomplished by [___ inhibition and __ stimulation at the T__-L_ level. The somatic system via pudendal nerve (S2-4)

Voiding phase: When bladder is full, signal sent to brain, ___ input modulates the parasympathetic inhibition. Afferent cortical info from the stretch receptors of the bladder go to the brain. Sphincter relaxes and detrusor contracts.

Answer 1

Filling: involves relaxation of detrusor muscle, and contraction of sphincters. Accomplished by [parasympathetic inhibition and sympathetic stimulation at the T10-L2 level. The somatic system via pudendal nerve (S2-4)

Voiding phase: When bladder is full, signal sent to brain, cortical input modulates the parasympathetic inhibition. Afferent cortical info from the stretch receptors of the bladder go to the brain. Sphincter relaxes and detrusor contracts.

Question 2

Parasympathetic and peripheral innervation is important for normal voiding processes. Parasymp is innervated by the __ __ (S2-S4). This is mainly acting on detrusor. __ is main NT, acting on muscarinic receptors on the detrusor.

Sympathetic innervation is the __ __. At detrusor, its __ adrenergic, at internal sphincter, its __ adrenergic. SOmatic innervation is via __ nerve (nicotinic cholinergic external sphincter).

Answer 2

Parasympathetic and peripheral innervation is important for normal voiding processes. Parasymp is innervated by the pelvic nerve (S2-S4). This is mainly acting on detrusor. Ach is main NT, acting on muscarinic receptors on the detrusor.

Sympathetic innervation is the hypogastric nerve. At detrusor, its beta adrenergic, at internal sphincter, its alpha adrenergic. SOmatic innervation is via pudendal nerve (nicotinic cholinergic external sphincter).