Bowel-associated dermatosis arthritis syndrome (bowel bypass syndrome)

Question 1

What patients classically get bowel-associated dermatosis arthritis syndrome (bowel bypass syndrome)?

Answer 1

patients with jejunoileal bypass surgery and blind loops of bowel

Question 2

What causes the arthritis and dermatosis in bowel-associated dermatosis arthritis syndrome (bowel bypass syndrome)?

Answer 2

Bacteria in blind loop of bowel leads to immune complexes that get deposited in skin and synovium

Question 3

clinical presentation fo bowel-associated dermatosis arthritis syndrome (bowel bypass syndrome)?

Answer 3

• constitutional symptoms preceding rash
• red to purpuric papulopustules over proximal extremities and trunk
• EN-like lesions
• Diarrhea/malabsorption, hepatic failure, kidney stones, gallstones

Question 4

Treatment of bowel-associated dermatosis arthritis syndrome (bowel bypass syndrome)?

Answer 4

• Antibiotics and immunosuppressive agents lead to temporary improvement
• surgical correction of blind loop of bowel is curative