Borrelia

Question 1

Where are the flagella located in borrelia?

Answer 1

Periplasmic space

Question 2

Structure of borrelia?

Answer 2

Loose spirals

Question 3

What stain can be used for borrelia?

Answer 3

Giemsa and Wright

Question 4

disease caused by borrelia burgforgeri?

Answer 4

lyme disease
in US and europe
also caused by b afzelii and b garinii

Question 5

b recurrent causes

Answer 5

Louse borne relapsing fever

Question 6

Ticke borne relapsing fever is caused by

Answer 6

Various borrelia species

Question 7

What is the most common vector borne disease in the US?

Answer 7

Lyme disease

transmitted by ticks from genus Ixodes

Question 8

How long does the tick cycle of Lyme disease last?

Answer 8

2 yrs

Question 9

What are the hosts for the ticks that transmit Lyme disease?

Answer 9

larva and nymph - white footed mouse

adult - whitetail dear

Question 10

Which form of tick is responsible for transmission?

Answer 10

Nymph
during a blood meal, spirochaete ( borrelia) is transferred from the tick’s saliva
the human is an incidental host

Question 11

Red papule with central clearing

• name of lesion?
• stage?

Answer 11

Erythema migrans
bull’s eye
Stage 1 - early localised disease

Question 12

When does stage 2 occur?

Answer 12

weeks - months post infection

Question 13

multiple erythematous macule
confusion
achy joints
flu-like

Answer 13

Stage 2 lyme disease

early disseminated disease

Question 14

Features of stage 3 infection borellia?

Answer 14

months - yrs post infection
arthralgia, chronic arthritis
encephalopathy, peripheral neuropathy
bluish-red lesions on swollen -atrophic ankles and elbows

Question 15

Screening and Confirmatory test for Lyme disease?

Answer 15

Use ELISA to screen

Western blot = confirm

Question 16

Lyme disease treatment

Answer 16

• Early disease - oral 
— Doxycycline or amoxicillin 
— Cefuroxime 
• Late - oral or IV 
— Ceftriaxone or Penicillin G