Book Flashcards

1
Q

Units of length

A

CM, Feet

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2
Q

Units of area

A

Length squared
Cm squared
Ft squared

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3
Q

Volume

A

Length cubed
CM to the third power
FT to the third power

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4
Q

No exponent is between numbers____ and_____

A

1&10

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5
Q

10 to the -6

A

0.000001 is 10 to the -6 or mirco

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6
Q

Hz=

A

Cycles per second

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7
Q

How much bigger is 1 billion than 1 million?

A

1,000 times

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8
Q

Macro - bigger
Micro- smaller

A

True

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9
Q

Biologic effects

A

The effects of a sound wave upon the biologic tissue

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10
Q

Sound is a series of______ and_____

A

Compressions and rarefactions

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11
Q

Compressions

A

Areas of increased pressure and density

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12
Q

Rarefactions

A

Areas of decreased pressure and density

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13
Q

Sound is a mechanical, longitudinal wave

A

True

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14
Q

What are the three acoustic variables?

A

Pressure, density, distance

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15
Q

Pressure*

A

Concentration of force within an area
Force/area
Units-Pascals (Pa)

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16
Q

Density

A

Concentration of mass within a volume
Kg/cm 3

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17
Q

Distance

A

Measure of particle motion
Units- Distance
Ex- mm or cm

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18
Q

Transverse wave

A

Particles move in a perpendicular direction (right angles, or 90°)

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19
Q

Longitudinal wave

A

Particles move back-and-forth in the same direction as the wave

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20
Q

Compressions

A

Regions of higher pressure and density

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21
Q

Rare factions

A

Regions of lower pressure and density

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22
Q

Can a sonographer change period and frequency?

A

No

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23
Q

Can a sonographer change amplitude, power, intensity?

A

Yes

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24
Q

Acoustic variables

A

Identify which waves are sound waves

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25
Acoustic parameters
Describe the features of a particular sound wave
26
Period
The time required to complete a single cycle
27
Frequency
How often are cycle sent out The frequency of a wave is the number cycles of an acoustic variable that occur in one second
28
Frequency units
Per second Hz
29
Frequency values
2 MHz - 15 MHz
30
Lower frequency
Better penetration with decreased resolution
31
Higher frequency
Poor penetration with increased resolution
32
Frequency between 20 Hz and 20,000 Hz
Audible
33
Greater than 20,000 Hz
Ultrasound
34
Less than 20 Hz
Infra sound
35
Frequency and period are inversely related
When one goes up, the other goes down
36
When period is unchanged , frequency is____
Unchanged
37
Shorter period uses ____ frequency
Higher frequency
38
Longer period Uses ___ frequency.
Lower
39
Frequency and period equation
Frequency x Period
40
Amplitude, power, intensity. All decrease sound travels.
True
41
Amplitude
The difference between the average value and the maximum value of an acoustic variable. The variation of an acoustic variable. Units Pressure- Pascals Density- grams/ cubic cm Particle motion – centimeters, inches, units of distance
42
Power
The rate of energy transfer Units- watts * Power is proportional to the waves amplitude squared
43
Intensity
The concentration of energy in a sound beam Units- watts/ square cm or watts/cm squared
44
Amplitude, power, intensity are proportional to each other
When one goes up, the other goes up
45
Wavelength
The length or distance of a single cycle and influences image quality (axial resolution) Units- any units of length Determined by both the source and the medium
46
**Wavelength equation **
Wavelength(mm) = prop speed 1.54mm/us divided by frequency (MHz)
47
Higher frequency sound has shorter wavelengths (better imaging) Lower frequency sound has longer wavelengths
48
Wavelengths in soft tissue
In soft tissue, sound with a 1 MHz frequency has a wavelength of 1.54mm In soft tissue, sound with a 2 MHz frequency has a wavelength of 0.77mm
49
Propagation speed
The rate that sound travels through a medium (aka- velocity or speed) Units- meters per second mm/us Determined by medium only (density and stiffness)
50
Propagation speed
All sound travels at the same speed through any specific medium. Cant be changed by sonographer
51
Propagation speed values **
1,540m/s 1.54km/s 1.54mm/us
52
Speed and wavelength are directly related
Sound in a slow medium has a short wavelength Sound in a fast medium has a long wavelength
53
Tissue types**
Lung(air)<
54
Stiffness is related to change in shape “squishability” Density is related to weight
Stiffness & speed- same direction Density & speed- opposite directions
55
Bulk modulus *
Same as stiffness When bulk modulus increases, speed increases
56
Constructive & Destructive interference
In phase waves interfere constructively Out of phase waves interfere destructively
57
What are the units of intensity?
Watts/ cm squared
58
Units of power?
Watts
59
In diagnostic imaging, short, pulses of acoustic energy are required to create an atomic images
Continuous wave sound cannot create an atomic images. CW is used for Doppler.
60
Pulsed sound
 A pulse is a collection of cycles that travel together A pulse must have a beginning and an end, otherwise the sound is continuous wave
61
What are the five parameters that describe pulsed sound?
Pulse duration Pulse repetition period PRF Duty factor Spatial pulse length
62
Pulse duration
The actual time from the start of a pulse to end of that pulse Units-time, seconds Determined by sound source Changed by sonographer – no Typical values – 0.5 - 3us In clinical Imaging a pulse is comprised of 2 to 4 cycles Equation- pulse duration= number of cycles x period
63
Spatial pulse length
The distance from the start to the end of one pulse Units/distance, MM Determined by the source and the medium Sonographer cannot change Typical values/0.1 - 1mm Equation - SPL(mm)= # of cycles x wavelength(mm)
64
SPL affects mage quality (Axial resolution)
Shorter pulses create higher quality images
65
Pulse Repetition Period
Pulse repetition period (PR) is the time from the start of one pulse to the start of the next pulse. It includes one pulse duration and one listening time. Determined by Sound source Units - time, msec Changed by sonographer- yes Values- 100us to 1ms
66
As PR period increases, imaging depth increases. As PR period decreases, imaging depth decreases.
67
PRF
PRF is the # of pulses created by the system in one second. Hertz, Hz, per second Determined By sound source Sonographer can change it Values In clinical imaging, from 1,000-10,000Hz (1-10kHz) » • The PRF is determined by imaging depth only. Shallow image, higher PRF Deep image, lower PRF PRP/ PRF- one goes up, other goes down pulse repetition period (sec) × pulse repetition frequency (Hz) = 1
68
Duty factor
The percentage or fraction of time that the system transmits sound. Unitless Determined by sound source Can be changed by sonographer Typical values From 0.1% to 1% or 0.001 to 0.01 Shallow image, higher duty factor (little talking, lots of listening) » Deep image, lower duty factor Duty factor is always a small value, typically less than 1%. With deeper imaging, the duty factor is even smaller.» Note An imaging system must use pulsed ultrasound. Therefore, the duty factor always less than 100% Continuous wave sound has a duty factor of 100%. CW cannot create anatomical images.»
69
shallow imaging high pulse repetition frequency (PRF) short pulse repetition period high duty factor
deep imaging low pulse repetition frequency (PRF) long pulse repetition period low duty factor
70
Pulse duration, and SPL are determined by both source and medium
PRP PRF DF All determined by sound source
71
Intensity
The concentration of the power in a beam
72
Intensity keywords
• Peak the maximum value • Average the mean value • Spatial referring to distance or space • Temporal referring to all time (transmit & receive) •Pulsed referring only to the time the pulse exists (transmit only)
73
Intensity descriptions
SPTP- spatial peak, temporal peak **highest value SPTA- spatial peak, temporal average **most relevant for thermal bioeffects SATA- spatial average, temporal average **lowest value
74
Intensities
SPTA- related to tissue heating SPTP - greatest SATA -smallest
75
Logarithms
a novel way of rating numbers, a peculiar combination of addition and multiplication. The logarithm of any number represents the number of "1Os" that are multiplied together to create the original number. What is the log of 100? 10 x 10 = 100, the log of 100 is 2. What is the log of 1000? 10 x 10 × 10 = 1000, the log of 1,000 is 3.
76
Decibels
A logarithmic scale, a relative, comparison or ratio between the final to the initial strengths A comparison, therefore, two intensities are needed calculate decibels. Db report the of relative bigness of a sound beam
77
Positive decibels
Means getting bigger, the intensity is increasing 3 dB means two times bigger 10 dB means 10 times bigger
78
Negative decimals
Means getting smaller, the intensity is decreasing -3 dB means 1/2 -10 dB means 1/10
79
Attenuation
A decrease in strength, (intensity, power, and amplitude) have a sound wave as it travels. Unrelated to speed the further sound travels, the more attenuation occurs. Units -dB/must be negative since attenuation causes intensity to decrease Less attenuation = shorter distance/lower frequency More attenuation = longer distance/higher frequency
80
What are the three components of attenuation?
Absorption/primary sound converted into heat Scattering Reflection / 1%
81
Attenuation in different media
Air/ much more attenuation, then in soft tissue. Gel is used to remove air from the path of ultrasound. Lung and bone/bone absorbs and reflects. Lung scatters. Water/ much less than soft tissue Air>> bone & lung >> soft tissue>> water Attenuation and blood is less than that in soft tissue
82
Attenuation and penetration
In soft tissue, lower, frequency results in less attenuation. Thus we penetrate further with lower frequency sound.
83
Reflection**
Occurs when propagating sound energy, strikes a boundary between two media, and some returns to the transducer
84
Specular reflection
Occurs when the wave length is smaller than the irregularities in the boundary Strongest reflections are produced with normal incidence 90° These aren’t as well seen when the wave strikes the boundary at angles other than 90°. Example vessel wall.
85
Diffuse (Backscatter) reflection
The reflection of sound generally back towards the transducer, but in a number of directions When boundary is rough, reflected, sound is disorganized and random
86
Scattering
The distribution of sound randomly in all directions. Higher frequency, sound scatters to a great extent. **If a reflector is much smaller than the wave length of sound, sound is uniformly distributed in all directions
87
Rayleigh scattering
As frequency increases, scattering increases Blood is black due to Rayleigh scattering
88
Attenuation coefficient
The amount of attenuation per centimeter. A way to report attenuation without dealing with how far sound travels. Units- dB, dB per centimeters As frequency increases, the attenuation coefficient increases Remains the same, regardless of how far the sound waves travel Attenuation coefficient is half of the frequency
89
Impedance
A number associated with a medium. *It is Calculated not measured. Units- Rayls, Z Reflection of an ultrasound wave depends upon different acoustic impedances of the media on either side of the boundary *Equation- impedance (rayls) = density (kg/m3) X propagation speed (m/s)
90
Normal incidence
90°
91
Oblique incidence
Not 90°
92
In soft tissue, attenuation coefficient is directly related to_____
Frequency If frequency, doubles, attenuation coefficient, will double
93
The amount of Rayleigh scattering is related to____
Frequency If frequency, doubles Rayleigh scattering increases by a factor of 16 2x2x2x2=16
94
Normal incidence
Perpendicular Orthogonal Right angle 90° PORNN
95
Oblique incidence
Anything other than 90°/not at right angles
96
Reflection and transmission
Incident intensity- intensity of a sound wave prior to striking a boundary (100%) Reflected intensity -the intensity that after striking a boundary changes direction, and returns back from where it came from (less than 1% reflected) Transmitted intensity - the intensity that after striking a boundary continues on in the same direction that it was originally traveling (99%) Units W/CMsquared Incident= reflected + transmitted
97
Reflection and transmission
IRC/ intensity reflection coefficient- the percentage of the ultrasound intensity that bounces back when sound strikes a boundary ITC/ intensity transmission coefficient- the percentage of the incident intensity that after striking a boundary continues on the same direction that it was originally traveling No units, percentages Both are unitless Range from 0% to 100% or 0 to 1.0
98
Conservation of energy
Exists at a boundary
99
In biologic media
Boundary. Reflection % Soft tissue -air. 99% Soft tissue -bone. 50% Soft tissue- soft tissue. <1%
100
Reflection with normal incidence
**Reflection occurs only if the two media at the boundary have different acoustic impedances Intensity Reflection Coefficient (%) = Z2-Z1/Z2+Z1 squared With greater impedance differences between the two media, the IRC increases and the amount of reflection increases. Z= impedance
101
Transmission with normal incidence
Whatever is not reflected, must be transmit it 
102
Reflection and transmission with oblique incidence
Transmission and reflection may or may not occur with oblique incidence 
103
Refraction
Transmission with a band. Refraction is a change in direction at sound transmits from one medium to another. Requires both oblique incidents and different speeds Snells law describes the physics of refraction Sin(transmission angle) —— divided by——- Sin (incident angle) = Propagation, speed 2 ——-divided by———- Propagation, speed one
104
Angles
Smaller angle = slower medium Greater angle = faster medium
105
Time of flight
The time needed for a post to travel to and from the transducer, and the reflector is called time of flight or round-trip time What time of flight is measured we can determine reflector Depth Since the average speed of sound in soft tissue is 1.54 KM/SEC the time of flight and distance that sound travels in the body are directly related. Time of flight flight is increased by a factor of two. When one reflector is twice as deep as another pulses timer fly is doubled for the deeper reflector.
106
The 13 µs (microsecond) rule
In soft tissue, every 13 µs of go return time means the reflector is 1 cm deeper in the body.  Time of flight/Depth/ Distance trvld 13 µs 1 cm. 2 cm. 26 µs 2 cm 4cm
107
Speed equation
Speed= distance/ time
108
Piezoelectric effect
A property of certain materials to create a voltage when pressure is applied, or when the material is mechanically deformed
109
Piezoelectric materials
Synthetic- lead zirconate (PZT) aka/ ferroelectric material. Natural- quartz, tourmaline PZT ceramic Active element Crystal
110
Curie temperature Or Curie point
When PZT is heated above the temperature (approx 360°C or 680°F) its properties are destroyed, depolarized. Never heat sterilize or auto clave transducers
111
Sterilization
The complete destruction of all living microorganisms by means of exposure to heat, chemical agents, or radiation
112
Disinfection
The application of a chemical agent to reduce or eliminate infectious organisms.
113
Transducer architecture
Wire, case, backing material, crystal, matching layer Active element- Piezoelectric crystal, also called ceramic, PZT or crystal It is 1/2 wave length thick
114
Matching layer of transducer
The matching layer has an impedance between those of the skin and active element to increase transmission between the active element and the skin 1/4 wave length thick Impedances - PZT> Matching layer> gel> skin Going from the PZT crystal to the face of the probe, the impedance of each layer is less than less
115
Damping element, or backing material
Short pulses, create more accurate images Immaterial is bond it to the active element to reduce it’s ringing Z= impedance
116
Bandwidth and quality factor
The range of frequencies between the highest, and the lowest frequency emitted from the transducer Bandwidth (Hz)= highest frequency-lowest frequency Imaging probes are wide bandwidth or broadband because they use backing material Main frequency emitted is called the center, resonant, primary or natural frequency
117
Quality factor
A Unitless number related to extent of damping Low Q= damping, and wide bandwidth, Imaging transducers High Q= no damping and narrow bandwidth, CW and therapeutic transducers
118
Continuous wave transducers
Electrical frequency >>> sounds frequency
119
Pulsed transducers
The main frequency of sound from a pulse transducer is determined by two characteristics of the Crystal: 1) the thickness 2) propagation speed The propagation speed of PZT is approximately 4-6 mm/us When a PZT crystal is half as thick that sounds frequency is twice as high High frequency // Lower frequency Thin Crystal. Thick Crystal. Fast, PZT Slow, PZT Component // Thickness PZT crystal 1/2 wavelength thick Matching layer 1/4 wavelength thick
120
When a transducer is covered with a sterile cover with gel on the inside, what must the transducer avoid touching in order to create an image?
Talcum powder
121
Sound beams
Narrow beams create better images Starts out at exactly the same size as the transducer diameter or aperture Focus or focal point - the location where the beam reaches its minimum diameter Focal depth -the distance from the transducer to the focus. Also called focal length or near zone length. Near zone (Fresnel zone)-the zone in between the transducer and the focus. Sound beams coverage in the near zone. Far zone (Fraunhofer zone)-zone deeper than the focus, beyond the near field . Sound beams diverge in the far zone. Focal zone -the region surrounding the focus where the beam is sort of narrow and the picture is relatively good
122
Beam diameter
See picture
123
Focal depth
Distance from transducer to the focal point Determined by transducer diameter, or aperture and frequency Shallow Focus.- small diameter/low frequency Deep focus - large diameter/high frequency
124
Sound beam divergence
Describe the spread of the sound beam in the deep far zone Larger diameter, crystals, producing higher frequency, sound produced beams that diverge less in the far Field Smaller diameter crystals, producing lower frequency sound produced beams that diverge substantially in the far field
125
Diffraction pattern
V- shaped wave, also called Huygens wavelet
126
Huygens principle
The hourglass shape of an imaging transducers sound beam The overall hourglass shape of a sound beam is the result of the constructive and destructive interference of the mini sound wave. Let’s omit it from these numerous sound sources.
127
Axial resolution
The ability to distinguish two structures that are close to each other, front to back or along the beams main axis Units/ distance , mm cm Not changed by sonographer Short pulse means a short, spatial pulse length or a short pulse duration Images are more accurate with shorter pulses Typical values 0.05 - 0.5 mm Equation - Axial resolution (mm)= SPL(mm)/2
128
Axial resolution improves with
Less ringing(if you are cycles in a pulse) and higher frequency Higher frequency, transducers create more accurate images. As frequency increases, the numerical value of the axial resolution decreases.
129
Lateral resolution
The minimum distance that two structures are separated by side to side or perpendicular to the sound beam Units - distance mm Lateral resolution = being diameter Beam diameter, and lateral resolution varies with depth. Also called beam width variation, or point spread artifact Best at the focus or one near zone length from the transducer Degrades at deeper depths in the far zone
130
High frequency pulsed ultrasound
Improved axial resolution Improved lateral resolution in far field
131
Phased array
Adjustable or multi focusing Better overall lateral resolution Sonographer can move the focus to anatomic region
132
Focusing alters beam three ways
Narrow waist in the beam Shallower focus Smaller focal zone Focusing is effective, mainly in the near field and focal zone
133
Two types of focusing
Fixed- conventional or mechanical Adjustable by electronics called phased array
134
Mechanical scanning
One disc shaped element Active element mood by a motor, oscillating crystal or mirror Focusing/conventional or fixed Image shape/sector (fan) Defective, crystal/destroys entire image
135
Transducer arrays
A collection of active elements in a single transducer PZT cut into separate pieces called elements Combination of electronic circuitry, the wire, and the element Linear array/a collection of elements in a line. Linear switched (or sequential) and linear phase array Annular array/a group of ringed elements (bull’s-eye) with a common center Curvilinear array/elements arranged in an arc. Curvilinear, switched, or curvilinear phased.
136
Linear arrays (switched, or sequential)
Approximately 200 rectangular shaped elements 3 -10 but not all are fired at exactly the same time to create a narrow directional beam. Improving lateral resolution. No steering Parallel lines / rectangular shaped Defective crystal/drop out, extending from superficial to deep
137
Phased array’s
Adjustable, focus or multi focus electronically Approximately 200 rectangular shaped elements Electronic pulses delivered to mini or all elements and various patterns for each sound pulse. Sector shaped Time delays are called phase delays If one element malfunctions the staring and focusing become erratic Curvature pattern can change focal depth and amount of focusing The beam former creates the electronic patterns. 10 ns delays. Provides many focusing at many depths during reception 
138
Annular phase arrays
Rings, cut from the same circular slab a PZT. Looks like a bull’s-eye target. Small number of ring-shaped elements Selected focal zones. Inner crystals for shallow regions and outer crystals for deep regions. Small diameter rings, have a shallow focus, but divert rapidly Large diameter rings, have a deep focal length The image is pointed, fan, or sector shaped Multi focusing provides electronic, focusing and all planes at all depths Improved elevational resolution Steering is mechanically Defective, crystal/horizontal side to side drop out
139
Curvilinear arrays
PZT crystals arranged in a curve to provide a natural sector image Approximately 200 rectangular shaped elements Blunted sector, fan shaped image
140
Multi dimensional, arrays
2D arrays create 3D or 4D images 3D imaging more accurately measure is volumes of structures, such as cysts 4D Imaging is real time 3D imaging 3D Imaging quality is determined by the number of slices 3D Imaging provides more accurate value measurements
141
Vector arrays - trapezoidal imaging
Combined linear sequential and linear phased array technologies Trapezoidal shape / sector with a flat top Sector scanners are less useful when imaging superficial structures
142
Contrast resolution
Dynamic range Visualizing variety of gray shades in an image
143
Spatial resolution
Detail Affected by axial and lateral resolution, line density, and monitor
144
Temporal resolution
The ability to accurately locate moving structures are any particular incident in time Resolution pertaining to time **Depends only on frame rate. More images per second improves temporal resolution. Units / Hertz or per second Values / 20Hz - 100 Hz **Frame rate is determined by Imaging, depth and number of pulses **Limited by speed of sound, and imaging depth
145
Higher frame rate=
Better temporal resolution
146
Deeper imaging =
Lower frame rate
147
4 settings that affect temporal resolution
Sonographer controlled Maxximum Imaging depth Multi focus systems Sector size Line density
148
Temporal resolution improves-
When image is shallower or made of fewer pulses Less time to create an image More frames created each second
149
Temporal resolution, degrades-
When image is deeper or made of more pulses More time to create an image Frame rate decreases
150
Imaging depth
Shallow depth of you makes a frame faster and improves temporal resolution If Imaging depth is doubled, the frame rate will be halved 
151
Temporal resolution continued
Shallow Imaging Higher frame rate Better temporal resolution Deep Imaging Lower frame rate Worse temporal resolution
152
Single versus multi focus
Single focus- fewer pulses Higher frame rate Better temporal resolution Multi focus - more pulses Lower frame rate Worst temporal resolution
153
Sector size
Narrow sector- fewer pulses Higher frame rate Better temporal resolution Wide sector - more pulses Lower frame rate Worst temporal resolution
154
Line density
Low line density- fewer pulses Higher frame rate Better temporal resolution High line density - more pulses Lower frame rate Worst temporal resolution
155
Improved and reduced temporal resolution
Factors that shorten the time required to make each frame increase frame rate and improve temporal resolution Factors that lengthen the time required to make a frame will reduce frame rate and reduce temporal resolution
156
Frame rate vs. image quality
As temporal resolution improves (higher frame rate) image quality made degrade As temporal resolution degrades (lower frame rate) image quality may improve Increasing the line density degrades, temporal resolution, but improves spatial resolution Using multi focus, degrades temporal resolution by improves lateral resolution
157
Frame rate(FR) and time to create a frame (Tf)
Tf and frame rate are reciprocals Equation - Tf x FR = 1 Ex- 1/10th x 10 = 1 When one frame is created in 1/10 of a second, then the frame rate will be 10/second or 10 HZ
158
System components
Master synchronizer/organizes, synchronizes and times their functions so as to operate as a single integrated system Pulser/ controls the electrical signals sent to the elements. Creates the firing pattern for phased array system called being former. Transducer/converts electrical into acoustic energy during transmission Receiver/ the electronics associated with processing the electronic signal, produced by the transducer during reception, and producing a picture on display device Display/monitor, audio speakers Storage/computer memory, hard drives
159
Pulser
Receives timing signal from synchronizer. Produces electrical voltage up to 100 V that excites PZT Crystal during transmission. When the sonographer increases output power higher electrical voltages are created that strike the PZT crystals. This increases the sound intensity, created by the transducer and sent into the patient.
160
Pulser modes
Continuous wave/ continuous electrical signal Electrical frequency = sounds frequency Pulsed wave, single Crystal /short, duration, electrical, spike, one electrical spike per Ultrasound pulse Pulsed wave, arrays/mini elements fired for each ultrasound pulse. For phased array systems, the pulsar is also called the beam former.
161
Output power
Output power change the brightness of the entire image Signal-to-noise ratio changes Determined by the excitation voltage from the pulser PZT crystal vibrates with a magnitude related to pulser voltage Sonographer can change Brightness of the entire image changes
162
Signal to noise ratio (S/N)
High S/N ratio- high quality image Low S/N ratio- low quality image, degrades Increasing output power is the primary way to improve S/N ratio
163
Receiver functions order
Gain, TGC, dynamic range, reject Or Amplification Compensation Compression Rejection
164
Gain
Changes the brightness of the entire image. S/N ratio unchanged Adjusted by sonographer Units dB Every signal is treated identically (uniform amplification) Preamplification alters the signal before gain is applied. Usually performed in the probe Gain kill’s resolution
165
Compensation or TGC
Used to create uniform brightness Makes all echoes from similar reflectors appear identical regardless of depth Uniform from top to bottom Higher frequency = more TGC Lower frequency = less TGC
166
Dynamic range
Adjusts the grayscale range within the image Allows us to see all gray shades and differentiate tissues Changes the gray scale mapping Sonographers can adjust 
167
Reject
Illuminates, low level noise in our images Affects only low level signals everywhere on the image, but does not affect bright echoes. Fewer shades of gray. Sonographer can adjust 
168
Contrast agents
Micro bubbles of gas entrapped in a shell There is a large impedance difference between contrast agents and biologic tissues
169
Requirements for contrast agents
Safe Strong, reflector ultrasound Long persistence Metabolically inert
170
Output power vs gain
Adjustments to either output power, or gain alter the brightness of the entire image Output power affects patient exposure Gain doesn’t affect patient exposure Output power affects brightness, by adjusting the strength of the sound waves sent to the body from the transducer When the image is too bright due to high output power, the lateral and longitudinal resolution degrade Gain affects the brightness by changing the amplification of the electronic signals before returning to the receiver With increased gain, the electronic signals in the receiver, are boost it in the image will be brighter 
171
ALARA
As low as reasonably achievable
172
Lower frequency, transducers
To image deep, it is better to use a low frequency, transducer rather than increase output power
173
Harmonics
Harmonics are multiples of the transducer frequency Creates ULTRASOUND images by using reflections that are twice the transmit frequency. Harmonics are created in the tissues, not in the transducer Nonlinear behavior creates harmonics Nonlinear is uneven Sound moves slightly faster in regions of compression (higher pressure) Sound travel, slightly slower in regions of rarefaction. (lower pressure.)
174
Pulse inversion, harmonic imaging
The major disadvantage is that the frame rate is half that a fundamental imaging. Pulse inversion, imaging degrades, temporal resolution (lower frame rate) well improving spatial resolution (image detail) Transducer bandwidth must include transmit and harmonic frequencies
175
Harmonics are multiples of the transducer frequency? True or false
True
176
Bistable vs. Grayscale.
Bistable: black or white On or off High contrast * Narrow dynamic range * Poor contrast resolution Grayscale : Many shades of gray Multiple levels Low contrast Wide dynamic range Good contrast resolution
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Brightness*
 Related to the brilliance of the image, how ‘lit up’ is the image
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Contrast
Determines the range of brilliance is that are displayed. Are the whites white? Are the blacks black? Bistable images are high contrast
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Analog and digital
Analog: Real world/a variable obtains, a continuum of values Ex- actual weight of an individual Digital: Computer world/a variable attains only discrete values Ex- measuring weight on a digital scale
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Scan converters
Changes the data format from penetrations to horizontal lines of a display
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Computer memory is called…
RAM Random Access Memory
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Digital scan converter
A microprocessor digitizes images. This converts the image into zeros and ones which are stored in memory. The numbers (*digital image data) can be processed and then re converted for display as an image
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Pixel
The smallest element of a digital picture ** Pixel density- the more pixels per inch, the more detail in the image, spatial or detail resolution ** Low pixel density/ poor spatial resolution High pixel density/ good spatial resolution *spatial resolution on a digital display is determined by the pixel density (the # of pixels per inch) * spatial resolution is also related to the # of lines per frame
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Bit
*Binary digit, the smallest amount of digital storage *a bit is a bistable, having a value of either zero or one *a group of bits is assigned to each pixel to store the gray scale color assigned to that pixel *the more bits per pixel the more shades of gray, and the better the contrast resolution Binary number- group of bits. A series of zeroes and ones Digital (computer based) means binary Ex- 101 or 00110011 *Byte- a group of 8 bits is a byte. 2 bytes (16bits) is a word Ex- Byte 12345678 Word 12345678 12345678 Note- Binary numbers are based on 2 Decimal numbers are based on 10 *
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* how to calculate the # of gray shades that a collection of bits can represent
How many bits are assigned to each pixel. Multiply the number 2 by itself the same number of times as there are bits. Thats the answer. Ex- what # of shades that can be represented by 10 bits? 2x2x2x2x2x2x2x2x2x2= 1024 Or 2 to the 10th power So the largest # of shades represented by 10 bits is 1024 Note- digital means binary, not decimal Examples pg 106
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Image processing Pre-processing
Manipulating the data before storage in the scan converter. Preprocessing cannot be reversed TGC Dynamic range Write magnification Fill in interpolation Persistence / frame averaging Special compounding
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Image processing Post processing
Manipulating the data after it has been stored in the skin, converter memory, but prior to display. This can be undone * post processing is performed on frozen images Read magnification 3-D rendering
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Analog digital conversion See pg 107/ pix
Analog / real world that we live in is analog Digital/ computers is digital Analog to digital conversion/electrical signals, created by the PZT are analog However, a digital scan converter can only process computer information. The analog signal must be converted into digital form for the input into the scan converter this is done by analog to digital converter
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Read and write magnification
Read magnification- Post processing Does not rescan, only reads old image data in memory Same line density Larger pixels Spatial resolution not improved Temporal resolution unchanged Write magnification - Preprocessing Rescans and requires new data, discard old image data Increased line density More pixels Improved spatial resolution * Temporal resolution can change **If pixel size is unchanged, the number of pixels increase (write magnification) If number of pixels is unchanged, pixel, size increases (read magnification)
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Spackle artifact
Imaging artifact *Grainy appearance and tissues, that does not represent actual tissue anatomy * created by interference effects of scattered sound Spackle reduces image contrast, and spatial resolution
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Clutter artifact
Doppler artifact With Doppler blood velocity measurements, the reflection from blood cells are weak. Reflections from anatomic structures are much stronger. These strong reflections are called clutter. 
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Fill in interpolation
Preprocessing Improves image detail (spatial resolution) by filling in the missing data, especially for deeper parts of a sector shaped image. Example/edges of a circular structure will be better defined
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Spatial compounding
Creating an image by averaging images obtained from different angles. Scan lines are steered by the system in different angles or views Phased array transducers only Frames are averaged, improving signal to noise ratio -artifacts reduced -spatial resolution (detail) improved -temporal resolution (frame rate) reduced - shadows and edge shadows are reduced or eliminated
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Temporal compounding or Persistence
Creating an image by overlaying images obtained at different times Also called temporal averaging Used in color flow Doppler Resulting image is a consolidation of past frames Temporal resolution is decreased Moving anatomic structures appear blurred Improves dynamic range, and contrast resolution
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Frequency compounding 
Creating an image by averaging frames obtained from different frequency sub-bands. Images are averaged, improving signal-to-noise ratio *Spackle artifact is reduced Spatial resolution is improved
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Dynamic aperture
Improves lateral resolution *A form of electronic receive focusing *Accomplished, by varying the number of elements used to receive the reflected signal Minimizes beam width variation
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Edge enhancement
Increases the contrast at a boundary to make image appear sharper Most useful to emphasize different tissues Distinguish interfaces
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Coded excitation
Takes place in the pulser Improves : Axial resolution Penetration Spatial resolution Contrast resolution coded excitation creates long sound pulses that contain a complex pattern of frequencies and cycles, called a code. Special mathematical techniques process the long reflected codes, creating high quality images
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Elastography
a dynamic technique that produces images, called elastograms, based on the deformation (change in shape) when an force is applied to tissue. The force is exerted a sound pulse from the transducer. Tissue stiffness is often related to underlying disease. identifies tissues of different mechanical properties, or different stuffiness
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Dynamic range
Ratio* of the largest to the smallest signal strength that each component processes, the number of choices indicates the number of gray shades on an image. Can eliminate low level noise* Units - dB* Transducers process using the widest dynamic range. Recoding device date has the lowest dynamic range
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Recording and Archiving
PACS- Picture archiving and communications system DICOM- Digital imaging and communications in medicine NAS- Network attached storage
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Hemodynamics Steady, pulsatile & phasic flow
Steady, pulsatile & phasic flow Steady flow- fluid moving at a constant speed Pulsatile- Arterial Cardiac High rate Higher pressure Phasic- Venous Respiration Low rate Lower pressure
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Hemodynamics Flow vs velocity
Flow- Volume How much? Volume/ time Liters/ min Velocity- Speed How fast? Distance/ time Meters/ sec
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Laminar flow
Plug or parabolic Plug flow Layers travel at same speed Parabolic flow Layers travel at individual speeds, highest in the center of the lumen
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Turbulent flow
Chaotic flow in many directions and speeds Associated with cardiovascular pathology and increased velocities (ex stenosis) *Turbulence may be identified as doppler spectral broadening Vortex- swirling pattern Eddy currents- turbulent flow
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Reynolds number
A unitless number, indicating whether flow is laminar or turbulent Reynolds #. Flow Less than 1500 Laminar Between 1500 and 2000 ???? Greater than 2000 Turbulent
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Bernoulli’s principle
Law of conservation of energy Describes the relationship between pressure (potential energy,) and flow (kinetic energy)
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Doppler shift Or Doppler frequency
a change or difference in the frequency of sound as a result of motion between the sound source and the receiver. Greater velocities create greater Doppler shifts. *difference between received and transmitted frequencies» positive/ change (or shift) when source and receiver are approaching each other. Reflected frequency is higher than transmitted.* negative/ change when the source and receiver are moving apart. Reflected frequency is less than transmitted frequency. *doppler measures frequency shift not amplitude Units- Hertz, cycles per second Values- * 20 Hz - 20kHz *audible Created when sound reflects off of moving red blood cells We still use 2 MHz to 10 MHz transducers to perform a Doppler ultrasound study. but the change in frequency (Doppler shift) ranges from 20-20,000 Hz.• Demodulation extracts the Doppler frequency from the transducer frequency and is performed by a demodulator. Bidirectional Doppler is analyzed with phase quadrature processing. Doppler shift = received frequency - transmitted frequency
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Doppler Equation ***
Doppler shift = 2 x reflector speed x incident frequency x cos (angle) —— Divided by ——— Propagation speed *** in order to accurately determine velocity, the angle between the directions of flow and sound beam must be known 
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Doppler shift is directly related to the…… **
Blood cell speed Transducer frequency Cosine of the angle between flow and the sound beam
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Doppler shift is inversely related to… **
The speed of sound in the medium
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What does the 2 in the doppler equation represent?
In clinical Doppler, there is a double Doppler shift. The first occurs when the sound strikes the blood cell. The second shift results from sound wave, reflecting off of the moving blood cell and returning back to the transducer. 
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Speed versus velocity
*Doppler measures velocity not speed Speed/ magnitude only Velocity/magnitude and direction * Doppler frequency depends on direction. The magnitude of shift depends upon the cosine of the angle between the sound being in the direction of motion. You need to know the angle to accurately evaluates velocity Equation - Velocity (measured)= True velocity x cos (angle) Angle Cosine 0° 1 (100% of the info parallel) 60° 0.5 90° 0 Maximum doppler shift at 0° No Doppler shift at 90° 
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Continuous wave Doppler
Two crystals in the transducer > one crystal is continuously transmitting > the other is continuously receiving Advantage/high velocity is our accurately measured.* Disadvantage/echoes arise from entire length of overlap between the transmit and receive beams called range ambiguity (doesn’t focus on specific area.) Range means depth CW can be thought of as a ‘Jet Sniffer’
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Pulsed wave doppler
One Crystal, alternates between sending, and receiving * Echoes arise only from the area of interrogation, the sample volume or gate. We locate the gate.(center of the lumen, parallel to vessel walls.)* Disadvantage/aliasing, errors in measuring high velocities And imaging and pulse Doppler can be performed with a single Crystal transducer Simultaneous Imaging and Doppler is known as duplex, ultrasound Axes- >the horizontal axis (or X axis, side to side) of a doppler spectrum is time. > the vertical axis (or Y axis, up and down) of a Doppler spectrum is Doppler shift or velocity.
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Aliasing
High velocities appear negative. With pulse Doppler, high velocity, measurements are inaccurate if the pulsed doppler sampling rate, the PRF, is too low in comparison to measured Doppler shift. Aliasing grows from top or bottom, never from the baseline Wrap around aliasing / with extremely high velocities High frequency transducers tend to show aliasing
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Nyquist frequency
The doppler frequency at which aliasing occurs, equal to half the PRF Equation- Nyquist limit (kHz) = PRF/2
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Eliminating aliasing
1) use CW doppler (CW has no aliasing) 2) use a lower frequency transducer/ it reduces the doppler shift & shrink the spectrum 3) select new view with shallower sample volume (this increases PRF & nyquist limit) 4) increase the scale 5) baseline shift (move baseline) *when the transducer frequency is halved, the measured doppler shift is halved *the calculated velocity will be the same regardless of the transducer’s frequency perform doppler at angles closer to 90°
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Relationship between sample volume size and Doppler spectrum **
Smaller sample volumes create doppler spectra with cleaner spectra window Larger sample volumes create Doppler spectra with filled in spectra (spectral broadening)
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Gray shades on a Doppler spectrum are related to: *
Amplitude or strength of the reflected signal Or Concentration of blood cells creating the reflection
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Pulsed vs cw Imaging vs doppler
Pg 124 See picture chart
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Color Doppler is based on pulsed ultrasound and is subject to:
Range resolution, or specificity* Aliasing *
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Color Doppler provides information regarding :
Flow direction
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Average or mean velocity
Color flow measures mean velocities (average) Pulsed and CW space Doppler measures. Peak velocity is.
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Color Maps
Top color/ always flow toward or closer to the transducer Bottom color/ always flow away from the transducer Velocity mode/colors on map do not vary side to side Variance mode/ colors on map very side to side
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No color in a vessel
The vessel is without color due to 90° incidence between sound being and flow The cosine of 90° zero
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Flow directions with color/sector probe
For a sector shaped image, look at the map. The flow direction is always from the top color to the bottom color. What is the vertical black line in the center of the vessel on a sector image? No Doppler shift because a normal incidence
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Velocity & Variance mode
Velocity mode/ colors show information on flow direction Variance mode/ colors show information on flow direction AND the presence or absence of turbulence Left side-laminar or parabolic (normal) Right side-turbulent or disturbed (pathology)
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Doppler Packets
Multiple pulses are called a packet, or ensemble length Small packets- Less accurate doppler Less sensitive to slow velocity or low flow High frame rate, improved temporal resolution Large packet- More accurate doppler More sensitive to fast velocity or flow Lower frame rate, reduced temporal resolution Advantages- Greater accuracy of velocity measurements Sensitivity to low flows Disadvantages- More time to acquire information Frame rate and temporal resolution are reduced The packet size must balance between accurate velocity measurements and temporal resolution Color doppler measures mean velocity ** color flow measures mean velocity **pulsed and CW measures peak velocity
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Color power doppler
Energy mode, color angio Direction and velocity are not calculated. Any measured doppler shift is simply colorized without consideration of direction or speed Advantages- *increased sensitivity to slow flows (venous flow, small and deeper vessels) *angle independent, not affected by doppler angles, unless the angle= 90° no aliasing Limitations- *low frame rates, poor temporal resolution No information on velocity or direction
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Roles for doppler modalities
CW doppler- identifies highest velocity anywhere along length of ultrasound beam PW doppler- accurately identifies the location of flow (range resolution) Has good temporal resolution. Color flow doppler- provides 2-D flow information directly on anatomic image. Power mode doppler- greatest sensitivity. Allows the use of color with low velocities or small volumes of blood flow
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Spectral analysis
Spectral analysis is performed to extract or identify the individual frequencies making up the complex signal. It is used to interpret individual velocities in the signal. *Techniques: Pulsed and CW doppler= fast fourier transform (FFT) Color flow- autocorrelation or correlation function *both FFT and autocorrelation are digital techniques that are performed by computers * Autocorrelation used for color doppler -determines average velocities -used for variance mode (pg128)
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Doppler artifacts Using the wall filter
*Also known as high pass filter Wall filters serve as a reject for doppler. Removed low level doppler shifts around the baseline. *rejects clutter Increasing scale will eliminate clutter *Wall filter may eliminate end diastolic flows from the spectral display, since they are the lowest velocities
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Cross talk
Found in spectral doppler only “Mirror image” Causes- Doppler gain set too high Incident angle near 90 degrees when flow is at focus
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What feature does pulsed wave Doppler have that continuous wave Doppler does not?
Pulsed wave Doppler has a receive gate that is adjusted by the sonographer.
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*hyperechoic
Tissues that appear brighter than normal “Brighter”
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Hypoechoic
Tissues that appear less bright than normal
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Anechoic
Without echoes
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Isoechoic
Equal echo brightness
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Homogenous
Similar echos
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Heterogeneous
Different echos within the image
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Artifacts
Reverberations- Multiple equally spaced Parallel to the sound beam Appears like a ladder Created when ultrasound ping-pongs between reflectors Comet tail or ring down - Single, solid, hyperechoic line Parallel to sound beam Shadowing - Shadow is background color (too few reflections on the scan) Too much attenuation Hypoechoic or anechoic region beneath Absence of true anatomy on scan in the region of the shadow Parallel to sound beam Edge shadow or shadowing by refraction - Eliminated by spatial compounding * Hypoechoic color Often along the edge of a curved reflector Enhancement - Results from too little attenuation in the structure above the artifact Hyperechoic Mirror image - Extra reflections on the skin Artifact located deeper than the true reflector
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Propagation speed errors
*Speed errors appear as a step off, split, or cut When speed is faster than soft tissue / reflector beneath will be placed to shallow on the display When speed is slower than soft tissue/ reflector beneath will be placed too deep on the display Fat/ sound travel slower than 1540 ms in fat. Reflectors beneath that may be placed too deep on the display. 
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Refraction artifact
Cannot identify refraction artifact from true anatomy with a single static image -Artifact appear side-by-side with the true anatomic structure -Sound can change direction or bend while transmitting -Occurs with oblique, incidence and different speeds Degrades lateral resolution
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Side lobes and grating lobes
-Artifact appearance, side-by-side with the true anatomic structure -occurs when reflections arise from off axis sound * mechanical transducers create side lobes * array transducers create grading lobes * grating lobes can be reduced by dividing each element into even smaller pieces. This is called subdicing. Grading lobes are further reduced by exciting the sub diced elements with different voltages. Center of the sound beam are excited with high voltages and outer most further away from the center. Excited with low voltage is. This is called apodization, which reduces lobes. * lobe artifacts, degrade lateral resolution With lobe artifact, the assumption that reflections arise from the beams, main axis are violated
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Slice thickness
Slice thickness, artifact occurs when beam has a greater width than the reflector This is called elevational resolution Phil and I have an anatomic structure is called partial, volume artifact, or section thickness, artifact *Generally, linear array transducers, have poor, elevational resolution
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Speckle
*Grainy appearance * created by interference effects of the scattered sound 
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Range ambiguity artifact
Created by reflection from structure, located deeper than the maximum imaging depth Fixed by changing depth
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Doppler phantom
Tests flow Used to assess the accuracy of pulsed, continuous wave and color flow systems Vibrating string and moving belt phantoms maybe used to evaluate dollar systems
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Sensitivity performance measures
When adjustments make changes in display or echo brightness from scarcely visible to fully saturated, sensitivity is being assessed
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Organizations
SDMS/society of diagnostic medical sonographer’s -Assists in acquisition of data * acquires, and reviews data OSHA / occupational safety, and health administration -Regulatory agency * regulates
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Measuring the output of ultrasound machines
Hydrophone/a small needle with a Piezoelectric crystal at the end. Measures the pressure in a sound beam. Calorimeter/a transducer that turns acoustic energy into heat Thermocouple/ a small device and better in absorbing material. The intensity at specific locations are measured. ** the exam duration is the greatest way to decrease exposure
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In-VIVO and in-Vitro
In VIVO- in the natural setting In vitro- anything else; literal meaning in glass Difficult to study in vivo(living tissues) due to absorption, scattering, and reflection
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Dosimetry
The science of identifying, and measuring those characteristics of an ultrasound field, which are especially relevant to its potential for producing biological affects
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AIUM
American Institute of Ultrasound in medicine Evaluates science
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FDA
Food and drug administration Regulates
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Bioeffects intensity limit-
SPTA 100mW/cm squared unfocused 1,000mW/cm squared focused
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Study techniques
Mechanistic approach/ Identify “cause-effect” relationship Empirical approach/ Identify “exposure-response”. relationship
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Thermal mechanism
Tissues/bone is an absorber Fetal tissues/fetal soft tissues adjacent to bone are of great concern/greater harm than adults SPTA/related to tissue heating Any exam that causes the temperature elevation two greater than 41°C is considered potentially harmful to a fetus Thermal index is a number proposed in the most recent AIU, and guidelines that relates to tissue Heating
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Non-thermal (cavitation) mechanism
Gaseous nuclei/ microbubbles Mechanical index/a number proposed in the a RUM guidelines that relates to cavitation Higher with peak rarefaction pressure and lower frequency sound. -Micro bubbles get bigger during the rarefactions -cavitation is more likely to occur in lung than other tissues Equation- *MI=peak rarefaction pressure/freq
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Stable cavitation
Bubbles intercept, redirect and absorb acoustic energy. Effects *shear stresses & microstreaming in surrounding fluids
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Transient cavitation
Bubbles expand during rare factions, and the bubbles burst TIN- Transient Inertial Normal Threshold is 10% greater than stable cavitation Highly localized violent effects/ Enormous pressures/mechanical stress Colossal temperatures /thousands of degrees
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Epidemiology and statistics
Population studies/large number of patients, clinical studies, ultrasounds ***Best study is perspective and randomized ** Limitations Often retrospective Ambiguities Other risk factors, such as age nutrition Etc Potential benefits should outweigh the risks AIUM suggests/ Don’t perform studies without reason Don’t prolong studies Minimize exposure ALARA principal - use minimum output, power, and highest game