Bone Tumors and Tumor-like lesions

Question 1

Bone forming tumors include:

Answer 1

1. Benign:
   
   1. Osteoma
   2. Osteoid Osteoma
   3. Osteoblastoma
2. Malignant
   
   1. Osteosarcoma

Question 2

Cartilage forming tumors include:

Answer 2

1. Benign
   
   1. Osteocondroma
   2. encondroma
   3. chondroblastoma
2. Malignant
   
   1. Condrosarcoma

Question 3

Fibrous Bone tumors

Answer 3

1. Benign
   
   1. Fibrous Cortical Defect/non ossifying fibroma
   2. Fibrous Dysplasia
2. Malignant
   
   1. Fibrosarcoma

Question 4

What are other tumors of bone?

Answer 4

1. Benign
   
   1. Giant Cell (osteoclastoma)
   2. Aneurysmal Bone Cyst
2. Malignant
   
   1. Ewing Sarcoma

Question 5

What is the first imaging study for bone lesions?

Answer 5

Plain film x-ray

Question 6

What are the characteristics of Gardner Syndrome?

Answer 6

FAP

osseous and soft tissue tumors

congenital hypertrophy of retinal pigment epithelium

(impacted/supernumerary teeth)

Question 7

FAP is a mutation of what gene?

Answer 7

AD mutation of APC

Question 8

What type of tumor is typically found on the surface of facial bones?

Answer 8

osteoma (benign)

Question 9

A 22 y/o presents with nocturnal bone pain that is improved by taking aspirin

Answer 9

osteoid osteoma

Question 10

A 22 y/o comes in to the office with back pain that doesn’t respond to aspirin

Answer 10

osteoblastoma

(benign)

Question 11

A 14 year old with a family history of blindness comes to the office complining of knee pain.

What type of tumor is most likely?

Answer 11

Based on the family history (retinoblastoma) the teen has an increased risk for Osteosarcoma (malignant)

Question 12

This malignant bone matrix producing tumor most often occurs in the metaphyseal region of long bones

Answer 12

Osteosarcoma

Question 13

This type of tumor arises from a lateral projection of the growth plate and is contiguous with the marrow space. It has a cartilage cap

Answer 13

Osteochondroma

Question 14

Condromas are benign tumors of?

Answer 14

hyaline cartilage that arise within the medullary cavity

Question 15

what type of tumor has a preference for the hands and feet (small bones)?

Answer 15

Condromas (benign cartilage producing tumors)

Question 16

What are the characteristics of Maffuci syndrome?

Answer 16

Enchondromatosis (multiple enchondromas)

and hemangiomas

Question 17

Condrosarcoma

15% arise from a preexisting?

Answer 17

enchondroma or osteochondroma

Question 18

This is a cartilage producing tumor that usually arises in the central portions of the skeleton including pelvis, shoulder, and ribs.

it commonly presents as a painful, progressively enlarging mass

Answer 18

Chondrosarcoma