bone tumors

Question 1

Most malignant tumors are

Answer 1

painful

Question 2

aggravating behaviors of malignant bone tumors

Answer 2

weight bearing

Question 3

most benign tumors dont have

Answer 3

soft tissue masses

Question 4

soft tissue tumors are often

Answer 4

mobile over the bone

Question 5

osteoid osteoma is

Answer 5

benign but painful

Question 6

radiographic features of bone tumors

4 of them

Answer 6

1) destruction of bone
2) periosteal reaction
3) soft tissue mass
4) matrix produced by tumor

Question 7

Sunburst
onion-skinning and
codman’s triangle are
signs of

Answer 7

malignant periosteal reactions

Question 8

Periosteal neocortex is a sign of

Answer 8

benign periosteal reaction

Question 9

Sunburst or hair ends
and osteoid matrix
are typical features of

Answer 9

osteosarcoma

Question 10

What is codman’s triangle

Answer 10

an angle of new bone that is formed along the cortex as the periosteum is lifted up by the tumor

Question 11

Onion-skinning is a feature of

Answer 11

ewing’s sarcoma

Question 12

A thing egg shell of new bone formed by periosteum is

Answer 12

neocortex -

and is benign aggressive

Question 13

CLouds of bone that has been formed in medullary canal or soft tissue is

Answer 13

osteoid matrix - feature of osteosarcoma

Question 14

punctate or popcorn calcification is a feature of

Answer 14

benign or malignant chondromas

- chondroid matrix

Question 15

ground glass/ hazy matrix is

Answer 15

fibrous matrix

Question 16

only benign tumor that will destroy bone is

Answer 16

giant cell tumor

Question 17

no soft tissue mass
normal ROM
no malignant radiographic features
but some matrix lesions
punctate calcifications

Answer 17

endochondroma - hyaline cartilage involving medullary bone

Question 18

where do endochondromas occur?

Answer 18

small bones of hands and feet

long tubular bones

Question 19

how large are endochondromas

Answer 19

< 3cm
white-grey
translucent
often multi-nodular

Question 20

how do endochondromas look like histologically

Answer 20

resemble hyaline cartilage

lack invasion

Question 21

A tumor composed of hyaline cartilage

Answer 21

chondrosarcoma

Question 22

sites of involvement of chondrosarcoma

Answer 22

pelvis
long tubular bones
ribs

Question 23

gross features of a chondrosarcoma

Answer 23

large
blue-grey
translucent
destructive

Question 24

how do you treat a chondrosarcoma

Answer 24

no chemorad

- SURGERY -

Question 25

13 yr old F
pain and swelling
Fever and night sweats
Soft tissue mass
onion skinning

Answer 25

ewing sarcoma

Question 26

sites of involvement of ewing’s sarcoma

Answer 26

• pelvis, ribs

long bones - diaphysis

Question 27

Soft/friable tumor
tan-grey
hemorrhagic or necrotic

Answer 27

ewing’s

Question 28

Microscopic identification of ewing’s sarcoma

Answer 28

Small round cell tumor

scant cytoplasm, lots of glycogen

Question 29

malignant tumor very responsive to chemo

Answer 29

Ewing’s

Question 30

22 yr old
limp, effusion at knee 
swelling, tenderness, dec ROM
eroded and neocortex egg shell
neoplastic mononuclear cells

Answer 30

Giant cell tumor

Question 31

hemorrhagic

Mononuclear cells interspersed with reactive osteoclast type GIANT cels

Answer 31

giant cell tumor

Question 32

Tumor in which the metaphysis of long bones is involved

flat bones and spine on occasion

Answer 32

Giant cell tumor

Question 33

16 yr old F
progressive pain and swelling in left knee
tenderness, effusion
Osteoid - dense bone formation with soft tissue mass
sunburst

Answer 33

osteosarcoma

Question 34

tumor in which the neoplastic cells produce osteoid matrix

Answer 34

osteosarcoma

Question 35

two tumors that involve METAPHYSIS

Answer 35

OSTEOSARCOMA

GIANT CELL tumors

Question 36

large fleshy hard
gray-white necrotic
granular or densely sclerotic
transgresses cortex with soft tissue mass

Answer 36

osteosarcoma

Question 37

which tumors do not respond to radiotherapy

Answer 37

osteosarcomas

chondrosarcomas

Question 38

70 yr old 
cachectic
clubbing 
lymphadenopathy
lytic lesion 
erosion of cortex, no soft tissue mass or periosteal reaction

Answer 38

Metastatic disease with bone destruction

Question 39

first treatment for bone mets

Answer 39

radiotherapy