bone structure Flashcards

1
Q

long bone has two parts

A
  • diaphysis
  • epiphysis
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2
Q

diaphysis

A
  • tubular shaft
  • runs between proximal and sitar ends of bone
  • hollow region: medullary cavity; filled with yellow marrow
  • walls are composed of dense and hard compact bone
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3
Q

epiphysis

A
  • wider section at each bone
  • filled with spongy bone
  • red marrow fills the spaces in spongy bone
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4
Q

what is the metaphysis in a bone

A

narrow area where the epiphysis meets the diaphysis and contains the epiphyseal plate (growth plate) in a growing bone

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5
Q

what happens to the epiphyseal plate when a bone stops growing?

A
  • bone growth stops around 18-21
  • epiphyseal plate is replaced by osseous tissue=becoming the epiphyseal line
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6
Q

what is the endosteum and what is its function

A

delicate membranous lining inside the medullary cavity where bone growth, repair and remodelling occur

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7
Q

what is the periosteum and what does it do

A

-fibrous membrane covering outer surface of bones except at joints
- contains blood vessels, nerves, lymphatic vessels that nourish compact bone and serve as an attachment point for ligaments and tendons

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8
Q

role of articular cartilage in bone joints?

A
  • thin layer covering epiphyses where bones form joints
  • reducing friction
  • shock absorber
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9
Q

what is the diploe? (hint- flat bone like the cranium, how do they protect internal organs?)

A
  • flat bones consist of a layer of spongy bone ; diploe : between two layers of compact bone
  • this helps protect internal organs even if the outer layer fractures, the brain remains protected by the intact inner layer
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10
Q

what is the role of collagen fibres in bone

A

provide a surface for inorganic salt crystals to adhere to give bones flexibility, preventing them from being brittle

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11
Q

what are hydroxyapatite crystals and their role in bone

A
  • made from calcium phosphate, calcium carbonate and other inorganic salts form on collagen fibres and give bones their hardness and strength
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12
Q

how much bone volume is composed of bone cells?

A

small amount of bone volume but crucial to its function

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13
Q

4 types of bone cells?

A
  • osteoblasts
  • osteocytes
  • osteogenic cells
  • osteoclasts
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14
Q

osteoblasts

A
  • form new bone by synthesizing and secreting the collagen matrix and calcium salts
  • found in growing bone areas like the periosteum and endosteum
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15
Q

what happens to osteoblasts as the bone matrix calcifies?

A

as bone matrix calcifies around osteoblasts, they become trapped and transform into osteocytes, the primary cell of mature bone

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16
Q

function of osteocytes in bones?

A

maintain the mineral concentration of the bone matrix and receive nutrients and help communicate with other osteocytes through long cytoplasmic processes extending through canaliculi channels within the bone matrix

17
Q

osteogenic cells

A
  • only bone cell that divides
  • immature osteogenic cells are found in deep layers of periosteum and the marrow
  • differentiate and develop into osteoblasts
18
Q

what bone cell is responsible for bone reabsorption or breakdown?

A

osteoclasts

19
Q

osteoblasts

A
  • found on bone surfaces
  • multinucleated
  • originate from monocytes and macrophages
  • break down old bone and form new bone
20
Q

which cells help reshape bone

A

osteoclasts and osteoblasts

21
Q

what is compact bone

A
  • denser, stronger of the two types of bone tissue
  • can be found deep in periosteum and in diaphyses of long bones where it provides protection and support
22
Q

what is basic structural unit of compact bone?

A
  • called an ‘osteon’ or Haversian system
23
Q

what are lamellae in bone

A

concentric rings of calcified matrix that make up the osteon

24
Q

function of the central Haversian canal in an osteon

A

central canal contains blood vessels, nerves and lymphatic vessels that supply the bone

25
volkmann's canals
perforating canals that carry blood vessels and nerves from the central canal to the periosteum and endosteum
26
where are osteocytes located in the bone
located in small spaces called lucunae, found at the borders of adjacent lamellae
27
how do osteocytes communicate and get nutrients
through tiny channels called canaliculi which connect the lacunae and eventually lead to central canal
28
what is spongey bone also known as
also called cancellous bone
29
how are osteocytes arranged in spongey bone?
housed in lacunae, but not arranged in concentric circles (like hard bone) - in lattice-like structure called trabeculae
30
what are trabeculae?
matrix spikes that form a lattice-like network in spongey bone, providing strength by aligning along lines of stress
31
how does spongey bone make bones lighter?
spaces in trabeculae network reduce the density of the bone, making it lighter and allowing muscles to move bones more easily
32
hematopoiesis
- production of blood cells - In red marrow - found in spongey bones protected by trabeculae
33
how does spongey bone and medullary cavity receive nourishment
- from arteries that pass through compact bone via the nutrient foramen (small openings in the diaphysis)
34
what is the nutrient foramen?
nutrient foramen is a small opening in the diaphysis of the bone through which arteries enter to nourish the spongy bone and medullary cavity
35
how are osteocytes in spongy bone nourished?
nourished by blood vessels from periosteum that penetrate the bone, as well as blood circulating in the marrow cavities
36
what happens to the blood as it passes through the marrow cavities?
collected by veins, which then exit the bone through the nutrient foramen
37
what role do nerves play in bone
follow the same paths as blood vessels through the bone in metabolically active areas. - sense pain, regulate blood supply - play a role in bone growth
38