Bone pt 3 Flashcards
Intramembranous ossification
formation of bone without a cartilage template
locations of Intramembranous ossification
frontal and parietal bones, parts of occipital and temporal bones, most of mandible, clavicle and maxilla
osteoblasts secrete osteoid, which will then collect Ca salts and be called
a spicule
endochondral ossification
formation of bone from a cartilage template.
**hyaline cartilage
locations of endochondral ossification
most long and short bones
How does cartilage continue to grow within the epiphysis by
interstial cartilage growth
An increase in length results from
bone in metaphysis growing towards epiphysis as cartilage in epiphyseal growth plate continues to develop
An increase in width results from
bone growth in the osteogenic periosteum
In young people is bone development or resorption greater
bone development > bone resorption
In adults is bone development or resorption greater
bone development ~ bone resorption
Effects of HGH
influences bone growth by stimulating osteoblast and fibroblast formation.
If low HGH, bone density will be low
Scurvey
Vit C deficiency.
Affects collagen I: reduces matrix and bone development, delays healing
RIckets
Vit D deficiency in children.
ossification is disrupted therefore deformed bones and fractures likely
osteomalacia
prolonged vit D deficiency in adults.
newly formed bone does not ossify therefore fractures increase.
primary cells involved in osteoperosis
osteoclast and osteoblast
