Bone & Muscle ~ Histology Flashcards

1
Q

Inorganic constituents of bone matrix

A

Calcium hydroxyapatite (calcium phosphate)

Gives Rigidity to Bone

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2
Q

Extensions from lacunae are called

A

Canaliculi

Which joins with other canaliculi arising from neighbouring lacuni

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3
Q

Space between the lamellae is called

A

Lacunae

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4
Q

Osteoblast derived from

A

Osteogenic precursor cells

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5
Q

Canaliculi contains

A

Processes from osteocytes (located in the canaliculi)

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6
Q

Aggregation of muscle fascicle is called

A

Muscle

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7
Q

Organic constituents of bone matrix made up of

A

Dense bundle of collagen Fibres embedded in the ground substance

So, collagen and ground substance together is called Osteoid

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8
Q

The bone is made up of many layers

A

Called Lamellar Bone/Lamellae

Thin bony plate, In which calcium and collagen are deposited in ground substance

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9
Q

Osteocytes located in the

A

Lacuna

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10
Q

Characteristic of compact bone

A

Made up of lamellae, which has lacunae and canaliculi

Lamellae~arranged in concentric rings

In the Centre of ring ~ Haversian canal

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11
Q

Yellow Bone Marrow present in

A

Compact bone

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12
Q

Structures passing through Haversian canal

A

Nerves and blood vessels

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13
Q

Haversian canal along with lamellus is called

A

Osteon

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14
Q

Canal which connects 1 Haversian canal with the other Haversian canal or with Bone Marrow

A

Volkmann’s canal

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15
Q

Covering of each muscle is called

A

Epimysium

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16
Q

Cancellous bone / Spongy bone characteristic

A

Haversian canal is absent

Bone is arranged in the form of Trabeculae

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17
Q

Red bone marrow in spongy/cancellous bone present in

A

Inter trabecular space

18
Q

Trabeculae of spongy/cancellous bone has

A

Lacunae

Lucunae in turn consist osteocytes

Margins of Trabeculae has numerous osteoblasts and osteoclasts

19
Q

Compact bone is mainly found in the

A

Diaphysis

20
Q

Cancellous/spongy bone mainly found in the

A

Epiphysis

21
Q

Marrow cavity and space in the cancellous bone are filled with?

A

Bone Marrow

22
Q

Red bone marrow present in

A

Cancellous / Spongy bone

23
Q

Each muscle fibre is covered by

A

Endomysium

24
Q

Aggregation of muscle fibres is

A

Fascicle

25
Q

Trabecular System present in

A

Cancellous/Spongy Bone

26
Q

Consistency of Compact And Cancellous Bone

A

Hard/Ivory like ~ Compact bone

Spongy like ~ Cancellous Bone

27
Q

Skeletal Muscle Characteristics

A

Fibres run Parallel to each other

Flat Nucleus, found in periphery

Syncytium ~ formed by fusion of cells cytoplasmic mass containing numerous nuclei

28
Q

Haversian system Present in

A

Compact Bone

29
Q

Each fascicle is covered by

A

Perimysium

30
Q

Part of myofibril between 2 adjacent Z - Band

A

Sarcomere

31
Q

What is mineralization

A

Is a process in which calcium salts are deposited into the matrix under the influence of osteoblasts

32
Q

On the basis of pattern of development of bone, the bone is divide into

A

Three categories;

Membranous bones
Cartilaginous bones
Membranocartilaginous bones

33
Q

Membranous bones ossification?

A

These bones ossify from highly vascular membrane of primitive mesenchyme

At the centre of ossification, mesenchymal stem cells differentiate into osteoprogenitor cells which give rise to osteoblasts

Eg; skull and facial bones

34
Q

Ossification of cartilaginous bones

A

Bones ossify from hyaline cartilage

The deeper layers of the perichondrium surrounding the cartilage contain osteoprogenitor cells which help in the bone formation

Eg; bones of limbs, vertebral column, thoracic cage

35
Q

Ossification of membranocartilaginous bones

A

Ossify partly from cartilage and partly from mesenchymal condensations

Eg; clavicle, mandible, occipital, temporal, sphenoid

36
Q

A single sarcomere is defined as

A

The distance between two Z lines

39
Q

Cytoplasmic processes send signals to and exchange nutrients and waste products with the osteocytes within neighbouring lamellae via

A

Gap Junctions

39
Q

Thin (actin) filaments in the I-band are bound to structural proteins at the

A

Z-line

39
Q

Thick (myosin) filaments in the A-band are bound to structural proteins at the

A

M-line

39
Q

The region of the sarcomere in which myosin does not overlap with actin

A

H-band

39
Q

The region of the sarcomere in which actin does not overlap with myosin

A

I-band