Bone/Joint infections Flashcards

1
Q

Osteomyelitis

- what is it?

A

Infection of the bone

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2
Q

What are 3 ways that osteomyelitis can come about?

A

Haematogenous spread
Contiguous spread
Direct inoculatio (trauma surgeru)

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3
Q

In haematogenous spread to osteomyelitis, what is normaly affected, why?

A

Metaphysis due to slow blood flow in metaphyseal vascular loops

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4
Q

How does haematogenously spread osteomyelitis normally present?

A

Pus discharge from sinues

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5
Q

Who is at risk of haematogenous OM?

A
Infants and young children
Elderly patients
IV drug abusers
Central venous catheters
Joint disease
Immuno-supression
Trauma
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6
Q

Most common cause of haematogenous OM in neonates, children and adults?

A

S. aureus

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7
Q

In those with sickle cell disease/thalassaemia, what is most common micro-org responsible for haematogenous OM?

A

Salmonella species

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8
Q

Implant associated infections OM, most common microorg?

A

Coagulase-neg staphylococci

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9
Q

Radiography findings in OM?

A

2 week lag. Soft tissue swelling, periosteal thickening and focal osteopenia

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10
Q

What test can rule out OM?

A

Negative technetium diphosphonate test

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11
Q

3 primary sites for OM form contiguous spread?

A

Cellulitis
Septic arthritis
Diabetic foot infections

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12
Q

Septic arthritis

Similar to OM, what is an additional risk factor for SA specifically?

A

Steroid injection

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13
Q

Surgical treatment of SA?

A

Aspirate arthroscopic drainage or open washout

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14
Q

Medical treatment of SA?
Risk of N gon or E coli?
MRSA risk?

A

Flucloxacillin. alt clindeamicin
Ceftriaxone
Vancomycin

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15
Q

Prosthetic joint infections
- presentation?
Radiography?

A

Discharging sinus

Lucencies around prostheses

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16
Q

Treatment of PJI

  • 1 step
  • 2 step
A

Debridement and excision of joint
Antibiotic loaded cement –> permanent prosthesis

Remove joint and insert spacer +/- ABx
Samples for microbiology
6 weeks ABx
New prosthesis - stop ABx