bone infection Flashcards
what is osteomyelitis
bone infection
where is acute osteomyelitis seen?
in children following infection at the epiphyseal growth plates following haematogenous spread
where is chronic osteomyelitis seen?
in patients with limb neuropathy or ischaemia particularly in lower limbs of people with diabetes
presentation of osteomyelitis
red, hot, swollen, painful, decreased mobility
which organisms are commonly found in bone and joint infection
staphylococcus aureus primarily (especially in acute OM)
neisseria gonorrhoea
myobacterium tuberculosis (following respiratory TB)
what is Pott’s disease
TB affecting the vertebral bodies
what is septic arthritic
a joint infection
what organisms can cause septic arthritis
staphylococcus aureus
neisseria gonorrhoea
what is reactive arthritis?
arthritis observed in association with a variety of infections at other body sites
what two aspects should be aimed for in using antibiotics for bone infection and why?
high doses- ensure sufficient antibiotic penetrates into the bone
long period of time-reflects the relatively slow paced osteoblast/osteoclast activity
how is ceftriaxone given
by IV only once or twice daily
.˙. suitable for outpatient parenteral antibiotic therapy
ceftriaxone used against…
staphylococcus aureus
streptococcus pneumoniae
haemophilus influenza
what is ceftriazone used for?
first line for meningitis
how is doxycycline given?
per oral po only
doxycycline used against…
staphylococcus aureus streptococcus pneumoniae legionella pneumophila chlamidya trachomatis mycoplasma pneumoniae
