Bone and Soft Tissue Tumours Flashcards
1
Q
What is the incidence of primary bone tumours in the UK?
A
- osteosarcoma- 3/1,000,000/yr
- chondrosarcoma- 2/1,000,000/yr
- Ewing’s tumour- 1.5/1,000,000/yr
- malig. fibrous histiocytoma- < 1/1,000,000/yr
2
Q
What are features of bone tumours?
A
- mass
- pain
- on activity
- progressivly at rest + night
3
Q
What are the cardinal features of primary malignant bone tumours?
A
- increasing + unexplained pain
- deep-seated boring nature
- night pain
- difficulty weight bearing
- deep swelling
- osteosarcoma
- Ewing’s sarcoma
- chonrosarcoma
4
Q
What are investigations for bone tumours?
A
- XR
- calcification (synovial sarcoma)
- myositis ossificans
- phleboliths in haemangioma
- CT
- isotope bone scan
- MRI
- bloods
- biopsy
5
Q
What are clincal features of osteosarcoma?
A
- pain
- loss of function
- swelling
- pathological fracture
- joint effusion
- deformity
- neurovascular effects
- systemic effects of neoplasia
6
Q
What are treatments for bone tumours?
A
- chemotherapy
- radiotherapy
- surgery
7
Q
Bone is the most common site for secondary tumours, after what primary tumours?
A
- lung, breast, prostate, kidney, thyroid, GI tract, melanoma
- metastatic bone disease 25x more common than primary bone tumour
- vertebrae > proximal femur > pelvis > ribs > sternum > skull
8
Q
What is used to assess risk of pathological fracture in metastatic bone disease?
A
Mirel’s Scoring System
