Bone Flashcards
What tissues make up the musculo-skeletal system?
- Bone
- Cartilage
- Muscles and tendons
- Ligaments
Bone characteristics
Mechanical
Physiological
Mechanical structures
Structural
Protective
Physiological Structures
CA2+ Regulation
Blood Cell production in bone marrow
Components of bone
organic (35%) and inorganic (65%)
Organic
- Cells
• (osteoblasts, lining cells, osteocytes, osteoclasts)
– Matrix (mostly type 1 collagen) – gives bone flexibility
Inorganic
– Mineral content – hydroxyapatite – makes bone strong
– Hydroxyapatite = complex salt of calcium and phosphate
Locations on a bone
Diaphysis
Two Epiphyses
Types of Bone
Cortical/Compact
Cancellous/ Trabecular
Characteristics of cancellous/trabecular
- Lattice of fine bone plates
– Epiphyses of long bones, vertebral bodies and flat
bones
– Intercommunicating spaces in mesh filled with bone
marrow
– Reduces skeletal mass without compromising strength
Physical properties of bone
Material
Structural
Material properties
– Properties of the material itself independent of specimen – i.e. stress at which a sample of cortical bone breaks under compression • Density of bone – Cortical bone 1700-2000 kg/m3 – Lumbar vertebra 600-1000 kg/m3 • Compressive strength of bone – Femur (cortical) 131-224 MPa – Wood (oak) 40-80 MPa – Limestone 80-180 MPa – Steel 370 MPa
Structural
– Properties of a specific specimen
i.e. breaking force for tibia
– Much more difficult to define
Bone Skeletal Processes
Longitudinal Growth
Circumferential Growth
Bone Remodelling
Longitudinal Growth
– Endochondral ossification
– Primary ossification centre
– Secondary Ossification centre (Epiphyseal plates)
– Ceases when secondary growth plates fuse at adulthood (~18yrs)