Bone Flashcards
Ewing’s can be positive for…
cytokeratin
S100
desmin
Young patient, monotonous cell population, always think about….
Ewing’s
Radiologically looks permeative but histologically looks like very bland, almost acellular osteoid (or even amyloid-like)
Sclerotic osteosarcoma (these are high grade and aggessive but look benign!)
In a patient with multiple giant cell tumors of bone, consider this disease?
Paget’s
Looks like fibrous dysplasia
Low grade central osteosarcoma or parosteal osteosarcoma
Skinny “Kate Moss” giant cells
NOF
Obese, voluminous giant cells
Giant cell tumor of bone (note: nuclei of monocellular cells in background are the SAME as the giant cells- if they were not, then consider something higher grade like osteosarc)
?
seborrheic keratosis
?
epidermal nevus
?
acanthosis nigricans
?
ilven
?
nevus sebaceous
?
inverted follicular keratosis
?
clear cell acanthoma
?
actinic (solar) keratosis
