Bone Flashcards

1
Q

Bone matrix composition

A

collagen 1, water, proteoglycan, other non collagenous proteins, hydroxyapatite mineral

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2
Q

woven bone

A

collagen fibers that make up in random orientation

present in fetal developement and repairment

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3
Q

lamellar bone

A

sheets of bone made from lamallae

1 directional sheets every layer but different differections per layer for strength

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4
Q

osteoblasts characteristics

A

respond/secrete high levels of growth factors and cytokine
high levels of alkaline phosphatase
bone forming
seen on cell surfaces whether active or inactive
high amounts of ER and golgi to modify synthesize export proteins for bone formation

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5
Q

osteocyte functions

A

mechanosensors, secrete alot of cytokines for osteoblasts and osteoclasts modulation, detect microdamage

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