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PHARM.E2.Adrenergic Agonists and ANTagonists > BOLD TEXT DRUGS > Flashcards

BOLD TEXT DRUGS Flashcards

1
Q

EPINEPHRINE

A

Trade name: Adrenaline Chloride
Half life: short
Mechanism of action: alpha and beta agonist
Elimination: COMT-urine
Indication: anaphylaxis, shock, cardiac arrest, heart block

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2
Q

NOREPINEPHRINE

A

Trade name: (Levophed)
Half life: short
Mechanism of action: alpha agonist, beta ONE agonist
Elimination: MOA and COMT-urine
Indication: Acute hypOtension due to shock

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3
Q

DOPAMINE

A 
Trade name: DOPAMINE
Half life:~2min
Mechanism of action: beta agonist, some alpha agonist activity
Elimination: MOA and COMT
Indication: Cardiogenic shock
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4
Q

ISOPROTERENOL

A 
Trade name: (Isuprel)
Half life:short
Mechanism of action: beta agonist
Elimination: COMT-urine
Indication: Transient heart block, (broncho-spasm during anesthesia
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5
Q

DOBUTAMINE

A 
Trade name: (Dobutrex)
Half life:2-3 min
Mechanism of action: beta ONE agonist
Elimination: COMT-urine
Indication: short term RX for low cardiac contractility
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6
Q

TERBUTALINE

A 
Trade name: (Brethine)
Half life: (2.9)
Mechanism of action: beta TWO agonist
Elimination: (urine)
Indication: Prevent and reserve bronchospasm in asthma, bronchitis and emphysema
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7
Q

ALBUTEROL

A 
Trade name: (Ventolin)
Half life: (5hr)
Mechanism of action: beta TWO agonist
Elimination: (urine)
Indication: Bronchial smooth muscle relaxation
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8
Q

PHENYLEPHRINE

A

Trade name: (Neosynephrine)

Half life:

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9
Q

CLONIDINE

A 
Trade name: (Catapres)
Half life: (12-16hrs)
Mechanism of action: alpha TWO agonist
Elimination: urine
Indication: HypErtension, analgesia
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10
Q

AMPHETAMINE

A 
Trade name: (Adderall)
Half life: (10-13hrs)
Mechanism of action: Indirect sympathomimetic
Elimination: urine
Indication: ADHD
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11
Q

METHYLPHENIDATE

A 
Trade name: (Ritalin)
Half life: (2-3hr)
Mechanism of action: Indirect sympathomimetic
Elimination: urine
Indication: ADHD
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12
Q

EPHEDRINE

A

Trade name: Ephedrine
Half life: (3-6 hr)
Mechanism of action: Indirect sympathomimetic
Elimination: Urine
Indication: Pressor agent with anesthesia

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13
Q

PSUEDO-EPHEDRINE

A 
Trade name: (Sudafed)
Half life: (4.3-8hr)
Mechanism of action: Indirect sympathomimetic
Elimination: (LIVER)
Indication: Nasal decongestion
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14
Q

TYRAMINE

A 
Trade name: (tyramine)
Half life: normally VERY short
Mechanism of action: DISPLACES NE
Elimination: MAO
Indication: NOT therapeutic
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15
Q

PROPRANOLOL

A 
Trade name: (Inderal)
Half life: 4 hr
Mechanism of action: Beta blocker
Elimination: (liver)
Indication: HypErtension, angine due to arthesclerosis, MI
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16
Q

TIMOLOL

A 
Trade name: (Blocaden-po; Timoptic-opth)
Half life: 4hr
Mechanism of action: Beta blocker
Elimination: Lover
Indication: Glaucoma
17
Q

NADOLOL

A 
Trade name: (Corgard)
Half life: 20-24hr
Mechanism of action: Beta blocker
Elimination: Urine
Indication: Long-term angina, hypErtension
18
Q

ATENOLOL

A 
Trade name: (Tenormin)
Half life: (6-7hr)
Mechanism of action: Beta ONE blocker
Elimination: urine
Indication: HypErtension, angina, MI
19
Q

METOPROLOL

A 
Trade name: (Lopressor, Toprol)
Half life: (3-7hr)
Mechanism of action: Beta ONE ANTagonist
Elimination: Liver
Indication: Hypertension, long-term angina rx
20
Q

PINDOLOL

A 
Trade name: (Visken)
Half life: (3-4hr)
Mechanism of action: Beta ANTagonist (with partial agonist activity)
Elimination: Urine
Indication: Hypertension
21
Q

ESMOLOL

A 
Trade name: (Breviblock)
Half life: ~9 min
Mechanism of action: Beta ONE blocker
Elimination: (esterases in RBC)
Indication: supraventricular tachycardia
22
Q

PHENOXY-BENZAMINE

A 
Trade name: (Dibenzyline)
Half life: (24hr iv)
Mechanism of action: alpha blocker
Elimination: (conjugates to receptor)
Indication: Pheochromo-cytoma (small vascular tumor of the adrenal medulla, causing irregular secretion of E/NE, leading to attacks of raised blood pressure, palpitations, and headache)
23
Q

PHENTOLAMINE

A 
Trade name: (Regitine)
Half life: (19min)
Mechanism of action:alpha blocker
Elimination: (urine)
Indication: (test for pheochromocytoma) rx for pheochromocytoma before surgery, (catecholamine extravasation)
24
Q

PRAZOSIN

A 
Trade name: (Minipress)
Half life: (2.3hr)
Mechanism of action: alpha blocker
Elimination: liver
Indication: Hypertension
25
Q

DOXAZOSIN

A

Trade name: (Cardura)
Half life: 22hr
Mechanism of action: alpha ONE antagonist
Elimination: (liver)
Indication: (prostatic hyperplasia, hypErtension)

26
Q

TERAZOSIN

A 
Trade name: (Hytrin)
Half life: 12hr
Mechanism of action: alpha ONE blocker
Elimination: (urine and fecal)
Indication: Prostatic hyperplasia, hypertension

PHARM.E2.Adrenergic Agonists and ANTagonists (11 decks)

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