Body Fluid Compartments and Homeostasis Flashcards
Name the different body fluid compartments
A. Intracellular B. Extracellular 1. Interstitial fluid 2. Plasma C. Transcellular- fluid in transit the lumens of intestinal tract, lungs, kidneys, and bladder
Approximate volume of fluid in plasma
3 liters
Approximate volume of fluid in interstitial fluid
13 liters Bone- 2 liters Dense connective tissue- 3 liters Bulk- 8 liters
Approximate volume of fluid in transcellular fluid
1 liter
Approximate volume of fluid in intracellular fluid
25 liters
Describe the endothelial cells
- Between plasma and interstitial fluid
- Permeable to water and everything except large proteins
Describe epithelial cells (membrane)
- Between interstitial fluid and transcellular fluid
- Very selective (regulatory)
- Allows stuff to move in one direction
Describe plasma membrane
Very impermeable to electrolytes
How do four principle organs interface the internal environment
- Contents from external environment enter the lungs and intestinal tract
- Waste from the internal environment is eliminated by the kidneys, lungs, intestinal tract, and skin
Describe the balance between intake and output of water in the body
- Intake occurs through metabolism of fatty acids, water in food, and drink
- Output occurs through feces, insensible (vaporization in lungs and skin) water, and urine
- Output is regulated by kidneys
Concentration of major ions in blood plasma
Na= 142 mM K= 4.4 mM Cl= 102 mM Protein= 1 mM Osmolality= 290 mOsm
Concentration of major ions in interstitial fluid
Na= 145 mM K= 4.5 mM Cl= 116 mM Protein=0 mM Osmolality= 290 mOsm
Concentration of major ions in intracellular fluid
Na= 15 mM K= 120 mM Cl= 20 mM Protein= 4 mM Osmolality= 290 mOsm