Boards Prep: Ocular Disease: Book Flashcards
Trauma: Chemical Burns
- Epidemiology?
- Symptoms? (6)
- Signs?
- Pathophysiology?
- Common Alkali Agents (Worse one)?
- Common Acidic Agents?
- Normal pH of Tears?
- Sign of ISCHEMIA?
- Exposure to chemical/thermal agents. ~66% occur in industrial settings.
- Normal/decreased vision, Pain, FBS, Photophobia, Tearing, BLEPHAROSPASM
- Mild SPK to Sloughing of Epithelium. Conj. Injection, Chemosis, Ciliary Injection, AC RxN, Conj Hemes, Scleral and LIMBAL BLANCHING (Limbal = BAD: Eye will SCAR = COMPLETE BLINDNESS). SEVERE BURNS can INCREASE IOP.
- ALKALI Burns = WORSE Px d/t raising pH = breakdown of FAs = Faster Penetration. 2x’s more common than ACIDIC BURNS.
- MORE DANGEROUS (Most Common: CALCIUM HYDROXIDE); Ammonia. lye, magnesium hydroxide, lime (plaster, mortar, cement, mouthwash), Airbag residue.
- Hydrofluoric Acid, Sulfuric Acid, Nitric Acid, Chromic Acid, PAVA spray.
- 7.45
- Limbal Blanching
Trauma: Corneal Abrasion
- Epidemiology?
- Symptoms? (4-6)
- Signs?
- Hx of Trauma
- Sharp pain (esp after blinking); FBS, Photophobia, Tearing, Blurred vision; maybe AC RxN and Miotic pupil.
- Corneal defect. Stains w/Fluorescein w/NO SEI!
Trauma: Conjunctival Abrasion
- Epidemiology?
- Symptoms?
- Signs?
- Hx of Trauma
- Pain, FBS, Tearing
- Maybe Conj Injection, or Subconj Heme.
Trauma: Corneal and Conjunctival Superficial FBs.
- Epidemiology?
a. Most common Non metallic FBs? - Symptoms?
- Signs?
a. Metallic FBs usually have what surrounding them? - Upper EYELID FBs: usually cause what?
- Algar BRUSH will NOT GO THRU what?
- Hx of Ocular Trauma;
a. Vegetable matter, cloth particles, cilia, stone, glass. - FBS, Tearing, Redness, Photophobia, decreased vision.
- FB w/ or w/o Sterile Infiltrate. Corneal Edema and Mild AC RxN can occur.
a. RUST RING. - Linear, Vertical, Corneal Scratches.
- thru the STROMA!
Trauma: Ruptured Globe and Penetrating Ocular Injury
- Epidemiology:
a. Hx?
b. Common more in whom? - Symptoms?
- Signs?
- What Test should u perform and how do u perform it?
- a. Recent trauma
b. Males (3:1) esp. young to middle-aged males. - Blurred Vision, Pain, Photophobia, Redness, Tearing.
- Full thickness laceration, SEVERE Conj Heme, EOM Restriction, Leakage of intraocular contents, LOW IOP. POSITIVE SEIDEL’s SIGN, HYPHEMA, COMMOTIO RETINAE, Choroidal Rupture, Tractional RD.
- Seidel’s Test: want to know if a wound leak is present. Take Fluorescein Strip, put it at the wound site, and u will see what looks black and gel like stuff leaking out.
Trauma: Hyphema
- Epidemiology/Hx?
- Pathophysiology/Dx
a. Main cause d/t?
b. What 2 tests should NOT be performed and why?
c. What test is INDICATED? - Symptoms?
- Signs?
a. 8 Ball hyphema?
b. Microhyphemas? - Other possible Signs?
- What can occur in LATE STAGES of HYPHEMA?
- If there’s a significant increase in IOP, what should the pt do?
- Hx of blunt/penetrating trauma, Systemic Dx (sickle-cell retinopathy, clotting dz, etc), Idiopathic.
- a. Trauma to IRIS and/or CB.
b. Gonioscopy or Scleral Depression; Wait at least 1 month to prevent rebleeding, which is usually worse than original presentation.
c. B-SCAN if it’s occluding view of fundus or if u think there might be an RD.
3. Pain, Blurred Vision
- Blood in AC.
a. Black Hyphema that covers the entire AC (B-Scan; and Goldmann, but NO Gonio or Scleral Depression)
b. RBCs suspended in AC, seen with Slit Lamp.
5. Iris sphincter tears, Iridodialysis, cataract, lens subluxation, VOSSIUS RING (Pigmen ring) on Anterior lens capsule, Commotio Retinae, ANGLE RECESSION (60% of cases –> HIGH RISK for GLAUCOMA).
6. CORNEAL BLOOD STAINING. (~5% of pts: usually seen w/LARGE HYPHEMAS, rebleeds, elevated IOP, compromised Corneal endothelial cells)
7. Elevate their head ~30 degrees so RBCs can settle inferiorly and hopefully not continue to block TM.
Trauma: Idiopathic Hyphema
- Number 1 Cause?
- Always ask pt about the use of what meds?
- Consider ordering what blood tests?
- Sickle Cell and/or Clotting diseases should be considered in what ethnicities?
- TRAUMA
- Blood thinners (aspirin, NSAIDs, etc)
- CBC, Prothrombin time/partial thromboplastin time (PT/PTT), Sickle cell screen.
- AA, and Mediterranean Pts.
Trauma: Intraocular FB
- Epidemiology
- Symptoms
- Signs?
- Intraocular FBs
a. Types that can cause Major Inflammation?
b. Types that can stay in the eye for long periods of time w/o causing inflammation?
- Hx of Trauma. Consider Intraocular FB if injury from metal striking metal or if an object was flying at high speed towards the eye. DO NOT ORDER MRI if u suspect METALLIC FB.
- Decreased VA, Pain.
- FB seen on CT scan, B Scan; Iris Transillumination Defects, Distorted pupil, Hyphema, Cataract, Decreased IOP, + Seidel’s TEST. Microcystic Edema of Peripheral Cornea.
- a. Iron (BBs), Steel, Copper, Vegetable Matter
b. Glass, Stone, Precious Metals, Plastic.
Trauma: Orbital Fracture
- Epidemiology?
- Pathophysiology?
- Symptoms?
- Signs?
- What 4 things should you look for when u suspect this?
- What 2 tests should you not perform and for how long should you wait?
- Tell Pts not to do what?
- Hx of Trauma from a large object
- Usually Orbital Blow Out Fractures d/t MAXILLARY BONE in Posterior Medial Floor breaking.
- Pain, Binocular Diplopia, CREPITUS (crackling when blowing nose) and on palpation of medial orbital area.
- Depends. Subconj Heme, Enophthalmos, diplopia, step-off fracture of the orbital rim, globe ptosis, infraorbital hypesthesia, asymmetric monocular PDs (>3 mm difference), Hyphema, Angle Recession, etc.
- TRAPPED IR, damage to INFRAORBITAL NERVE (causes Hypoesthesia), + Forced Duction Test, PERIORBITAL CREPITUS (Orbitla Emphysema)
- Gonio and Scleral Depression; Wait at least 4 WEEKS after trauma.
- To not BLOW their nose w/in 48 hrs of trauma to limi risk of orbital infection.
Trauma: Commotio Retinae
- Epidemiology
- Pathophysiology?
- Symptoms?
- Signs?
- Hx of Recent Trauma
- Disruption of RPE and Photoreceptor Outer Segements. Usually resolves w/o Sequelae w/in 24-48 hrs. Permanent vision/VF loss can happen.
- Usually Asymptomatic. May have Acute Vision loss if trauma happens w/in the macula.
- Gray-White Discoloration in the retina; Called BERLIN’s EDEMA when found w/in the MACULA. May see Retinal Hemes or a Choroidal Rupture.
Trauma: Iridodialysis
- What is it?
- What does it look like on SLE?
a. Best seen with that technique? - Monitor Pts for what? Cause?
- Disinsertion of Iris Root from CB. (Weakest point of attachment)
- Peripheral Iris Hole
a. Retroillumination - Angle Recession Glaucoma; TM may be damaged secondary to trauma.
Trauma: Vossius Ring
- What is it?
- Cause?
- Pigment Ring on Anterior Lens Surface
2. d/t contact w/the Posterior Pigmented Iris Epithelium during Trauma
Trauma: Purtscher’s Retinopathy
- Retinopathy associated with what?
- What signs do we normally see with it? (3)
- ACUTE CHEST-COMPRESSION TRAUMA
2. Diffuse Retinal Hemes, Exudates, CWS
Trauma: Choroidal Rupture
- Occurs in what % of Blunt Ocular Trauma?
- Most common presentation?
- Associated with what risk?
- 5%
- single area or multiple areas of Subretinal Hemes, usually w/in TEMPORAL POSTERIOR POLE w/Crescent Shaped Tears Concentric to the ONH.
- Long Term Risk of CNV at margins of the TEAR (happens in ~5-10% of Pts)
Trauma: Eyelid Ecchymosis
- What is it?
- Bruise or Black Eye. d/t Leaking BVs in SUBCUTANEOUS TISSUE that’s likely d/t Trauma.
Trauma: Conjunctival and Corneal Lacerations
- What is it?
- What test should be done to see if an open globe wound is present?
- Px?
- What else can result from TRAUMA?
- Tear in corneal or Conj tissue, usually d/t Trauma
- Seidel’s Test
- Good; Unless laceration is in the Visual Axis.
- OPTIC NEUROPATHIES. Disc pallor seen several weeks later.
Prolapsed Orbital Fat
- Why does this occur as we age?
- What does it look like?
- Possible issues with it?
- d/t weakening of the Orbital Septum –> Extraconal fat to prolapse.
- Outpouching of skin in upper and lower lids
- Can cause lid malposition, exposure keratopathy d/t lid malposition; Ocular irritation, redness, tearing, blurred vision, etc.
Preseptal Cellulitis
- Epidemiology?
- Pathophysiology?
a. Ocular Infection
b. Systemic Infection
c. Skin Trauma - Signs?
- Young adults and children during WINTER. More common than orbital cellulitis.
- Infection ANTERIOR to ORBITAL SEPTUM
a. Acute Hordeolum (most common), Dacryocystitis
b. URI or Middle Ear Infection
c. Puncture wound, insect bite - Eyelid Edema, Erythema, Ptosis, Warmth. Hard bump on eyelid. No pain. Maybe mild tenderness.
NO SIGNS of Orbital Congestion
Orbital Cellulitis
- Epidemiology
- Pathophysiology
a. Sinus Infection
b. Orbital Infection
c. 2 other causes? - Most common cause in Adults?
a. In Children? - Symptoms?
- Signs?
- Prognosis?
- **Leading cause of Exophthalmos in Kids. Ask about Fever, Recent Sinus or dental infections, Trauma
- a. ETHMOID SINUSITIS is the most common. From here, infection can spread thru the Lamina Papyracea (Very thin)
b. Dacryoadenitis, Dacryocystitis, progression of Preseptal Cellulitis
c. Orbital Fracture, Dental Infection - Staph Aureus
a. H. Influenzae - Red eye, pain, decreased vision, HA, fever, general malaise, reduced color vision, APD, PROPTOSIS, DIPLOPIA w/PAIN on Eye movement (d/t EOM RESTRICTIONS)
- Eyelid Edema and Redness
- Can cause Cavernous sinus thrombosis, Brain Abscess, and/or MENINGITIS;
**Diabetics and immunocompromised Pts can get MUCORMYCOSIS (BAD!!!)…Fungal infection…life-threatening…Pt’s get “BLACK ESCHAR (Necrotic Tissue)”
Orbital vs. Preseptal Cellulitis
- Pts w/Orbital Cellulitis will have the following, while Preseptal Pts will not…(5)
- Decreased Vision, Proptosis, FEVER, Pain on Eye Movement, EOM Restrictions.
Thyroid Eye Disease (Graves’ Ophthalmology)
- Epidemiology
- Pathophysiology
- Symptoms?
- Signs?
- Females (8:1); 4th-5th decade of life; STRONGEST RISK FACTOR for developing TED: SMOKING (2-9x’s greater risk)
- AI: TSH Receptor Antibodies –> Cause major inflammation to EOMs and Orbital Tissue –> Thickening EOMs –> ON Compression. Hyperthyroidism. TED in 30-70% of PTs w/Graves’
- Prominent Eyes; Chemosis, FBS, Tearing, Photophobia, Pain, Diplopia, Decreased Vision, Color Vision Loss, Etc.
- U/L or B/L PROPTOSIS, UPPER LID RETRACTION, APD, Eyelid Erythema and Edema, Conj and Caruncle Injection, Decreased Color Vision; IOP can be increased in Primary and UPGAZE.
**MOST Common cause of U/L or B/L Proptosis in Middle-Aged Peeps
Thyroids: NO SPECS grading system
- N: No signs or symptoms
- O: Only signs but no symptoms. (DALRYMPLE’s SIGN: Stare appearance)
- S: Soft Tissue involvement (lid edema; Conj Chemosis)
- P: Proptosis
- E: EOM Involvement –> Diplopia. INFERIOR RECTUS affected first, then > MR > SR > LR
- C: Corneal Involvement (Punctate Keratitis, SLK, Ulceration)
- S: Sight loss d/t ON Compression. Enlarged EOMs at orbital apex –> Compressing the Optic Nerve –> Disc Edema, APD, Reduced Color Vision, VF Loss. Decreased VAs.
Signs
- Von Graefe’s Sign
- Kocher’s Sign
- Dalrymple’s Sign
- Upper Eyelid lag during Downgaze
- Globe lag compared to lid movement when looking up
- Lid retraction which gives a Stare Appearance.
Thyroid Eye Dz
- Diagnosis? (5)
- a. Forced Ductions to detect EOM Restrictions
b. CT/MRI to detect enlargement of the EOMs
c. Exophthalmometry to measure proptosis
d. VFs detect ON Compression
e. Blood Work (T3/T4/TSH)