Blue Baby and CHD Flashcards
Hypoplastic Left Heart Syndrome S/S
as PDA closes… Hypoxia, acidosis, CV collapse
Tx order for hypoxic, acidotic 2-10d old baby
O2, intubate, Dextrose, PGE, Gentamicin/Ampicillin
Intraembryonic blood vessels noted at day
20
the median heart tube is completely day
Days 21 – 23
heart starts beating on day
22
fetal circulation begins on day
Days 27-29
ductus venosus shunts blood from
umbilical vein -> Inferior Vena Cava allowing oxygenated blood to bypasses the liver
foramen ovale shunts blood from
Right atrium -> Left atrium allowing blood to bypass the lungs
Ductus arteriosis shunts blood from
Pulmonary artery -> Aorta allowing blood to bypass the lungs
First treatment for a BLUE baby?
Oxygen
Gestational Diabetes increases the risk for
Congenital heart defects by 2X
Umbilical vein PaO2 is 30-35 mmHg.
Fetus 70-80% saturated at this PaO2, why?
fetal Hgb functions to deliver O2 at a low O2 concentration
Fetal Hgb transitions at
~6months
Upon first breath, pulmonary pressure
Decreases, blood shifts from left to right
Upon first breath, systemic pressure
Increases, blood shifts from left to right
Foramen Ovale closes
functionally upon first breath, closed by 3 months
Ductus Arteriosus closes
2-3 days post birth, unless CHD is present
What may cause the Ductus Arteriosus to remain open past 2-3days
low O2 tension (hypoxia), PGE
In the fetus, the normal direction of the shunted blood is
Right side -> Left (bypass fetal lung)
What function does the PDA provide after birth in a baby w/ cyanotic CHD?
Provide a source of pulmonary blood flow
In the neonate, the normal direction of the shunted blood is
reverses, Left -> Right
Pulmonary resistance should drop by _______ in infants
6 weeks
What type of CHD’s present later (closer to 6 weeks)?
LEFT-TO-RIGHT shunts (ASD, VSD, PDA)
What S/S would you find in an infant with Persistent Pulmonary HTN?
Difficulty transitioning, differential pulse Ox sat > 10% (O2 sat in UE is normal, LE is low)
If you have a hole in the heart, what effects shunt flow?
Pressure
Main cause of CHD
No specific cause/Multifactorial
Maternal Gestational diabetes is associated with what CHD?
Transposition of vessels, VSD, Coarctation
Lupus is associated with what what CHD?
Complete heart block