Blood Vessels I Flashcards
What are the primary functions of blood vessels?
- Allow gas exchange: O2 supply to tissue & CO2 removal
- Carry nutrients
- Carry metabolic wastes
- Carry hormones and signaling substances
- Maintain tissue fluid
What changes occur in blood vessels with age?
- Largest arteries grow until age 25
- Intima and media involved
- Media stiffens starting at age 30 (lipid & calcium accumulation)
- Atherosclerotic plaques in the intima
- Calcification of the media of muscular arteries
- Coronaries can be threatened by plaque by age 25
Be able to identify the 3 tunics in a micrograph or section
Arteries and veins are composed of three tunics:
tunica interna
tunica media
tunica adventitia (externa)
Pulmonary circulation =
right atrium & ventricle
Systemic circulation =
= left atrium & ventricle
Which are more muscular, arteries or veins?
arteries
Tunica Intima
endothelium, basement membrane, subendothelial layer of loose CT, and an internal elastic lamina (in arteries)
Tunica Media
smooth muscle, variable amounts of elastic fibers and lamellae, reticular fibers, proteoglycans, and external elastic lamina (+/-)
Tunica Adventitia
fibroblasts, longitudinal collagen and elastic fibers, vasa vasorum (+/-)
What are the 3 layers of the heart?
epicardium (outermost)
cardiac muscle = myocardium
endocardium (innermost)
In elastic arteries, which layer is thickest?
tunica media is biggest
Describe elastic arteries
Aorta and its main branches
Physical properties of elastic arteries produce a more uniform pressure and flow
Describe Mixed or Musculo-Elastic Arteries
Parts of terminal abdominal aorta, iliac arteries, external carotids etc.
Transitional segments between elastic and muscular arteries
Large tunica adventitia
Describe muscular arteries
Most named arteries are of this type
Wavy IEL
Describe arterioles
Function to maintain blood pressure and reduce pressure ahead of capillaries