Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Hematology 2 > Blood Vasculature, Megakaryocytes, Platelets > Flashcards

Blood Vasculature, Megakaryocytes, Platelets Flashcards

(51 cards)

Start Studying
1
Q

The maintenance of circulatory hemostasis is achieved through process of balancing? 2)

A

Bleeding (hemorrhage) and clotting (thrombosis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the 4 components of hemostasis?

A

Vascular system
Platelets
Blood coagulation factor
Fibrinolytic component

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the processes involved in hemostasis following injury to a small blood vessel (5)

A

Blood vessel SPASM
Formation of PLATELET PLUG
CONTACT among damaged blood vessels, blood platelet, and coagulation proteins
DEVELOPMENT OF BLOOD CLOT around injury
FIBRINOLYTIC REMOVAL of excess hemostatic material to reestablish vascular integrity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

This includes all the blood vessels that EXIST OUTSIDE the heart

A

Blood vasculature

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

This transports NUTRIENTS TO organs/tissues and transports WASTE AWAY from organ/tissues in the blood

A

Blood vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Blood vessels includes (3)

A

Arteries and arterioles
Veins and venules
Capillaries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

They bring OXYGEN-RICH blood and nutrients AWAY from the heart to the tissues and organs

A

Arteries and arterioles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

They play a major role in NOURISHING ORGANS WITH BLOOD AND NUTRIENTS

A

Arteries and arterioles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

They are DEOXYGENATED blood BACK TO THE HEART and start again in superior vena cava for reoxygenation

A

Veins and venules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

A blood vessel that is ALWAYS UNDER HIGH PRESSURE

A

Arteries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Arteries has abundant elastic tissue and less smooth muscle to withstand pressure

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Presence of this protein in the large blood vessels enables vessels to INCREASE IN SIZE AND ALTER THEIR DIAMETER

A

Elastin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

A blood vessel that is SMALLER THAN ARTERIES but BIGGER THAN CAPILLARIES

A

Arterioles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

It connects arteries and capillaries

A

Arterioles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

A thin-walled blood vessel that is less elastic

A

Veins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

A blood vessel with LOW PRESSURE

A

Veins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

A blood vessel that can accommodate a LARGE VOLUME of blood

A

Veins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

A component inside the veins that allow for blood flow toward the heart in a forward direction

A

One-way valves

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

How many of the circulating blood volume is contained in the venous system?

A

3/4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Venous blood vessels that is ANALOGOUS IN SIZE WITH ARTERIOLES

A

Venules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

It connects veins and capillaries

22
Q

TINY blood vessels containing STRUCTURES THAT CONNECT ARTERIOLES TO VENULES

23
Q

These are the SMALLEST and MOST ABUNDANT FORM OF BLOOD VESSELS in the body

24
Q

A blood vessel that allows GAS EXCHANGE, NUTRIENT TRANSFER, and WASTER REMOVAL BETWEEN BLOOD AND TISSUE FLUIDS

25
What are the three layers of blood vessels?
Vascular INTIMA Vascular MEDIA Vascular ADVENTITIA
26
The inner layer of the blood vessels
Vascular intima
27
The middle layer of the blood vessels
Vascular media
28
The outer layer of the blood vessels
Vascular adventitia
29
The layer of the blood vessels where blood flows
Vascular intima
30
This provides INTERFACE BETWEEN CIRCULATING BLOOD and BODY TISSUES
Vascular intima
31
INNERMOST lining of blood vessels which is a monolayer of metabolically active endothelial cells
Vascular intima
32
SINGLE layer of SQUAMOUS epithelial cells that LINE the INTERIOR SURFACE of BLOOD AND LYMPHATIC VESSELS
Endothelium
33
It RELEASES SUBSTANCES that control vascular relaxation and contraction and PRODUCE ENZYMES that control blood clotting, immune functions, and platelet adhesion
Endothelium
34
Small proteins PRODUCED BY ENDOTHELIAL CELLS in a variety of tissues where they ACT AS MODULATORS OF VASOMOTOR TONE, CELL PROLIFERATION, and HORMONE PRODUCTION
Endothelins
35
Enumerate the 3 members of the endothelin family
Endothelin-1 Endothelin-2 Endothelin-3
36
The only endothelin family member PRODUCED IN ENDOTHELIAL CELLS and also produced in vascular smooth muscle cells
Endothelin-1
37
PRODUCED predominantly WITHIN KIDNEY AND INTESTINE with smaller amounts produced in myocardium, placenta, and uterus
Endothelin-2
38
Found in HIGH CONCENTRATIONS IN THE BRAIN and may regulate important functions such as PROLIFERATION AND DEVELOPMENT IN NEURONS AND ASTROCYTES. Also found throughout GI tract, lung, and kidney
Endothelin-3
39
Endothelins function is based on their location but generally ACTS AS MODULATORS of blood vessel tone which contributed to the integrity of blood vessel
True
40
What are the PROPERTIES of the VASCULAR INTIMA that INITIATE AND REGULATE HEMOSTASIS AND FIBRINOLYSIS
Anticoagulant property Procoagulant property Fibrinolytic property
41
Enumerate the 4 anticoagulant property of the vascular intima
Prostacyclin Nitric oxide Tissue factor pathway inhibitor (TFPI) Thrombomodulin
42
Inhibits platelet activation
Anticoagulant property
43
PLATELET INHIBITOR and VASODILATOR ; synthesized through the EICOSANOID PATHWAY and PREVENTS UNNECESSARY OR UNDESIRABLE PLATELET ACTIVATION IN INTACT VESSELS
Prostacyclin
44
Synthesized in ECs, vascular smooth muscle cells, neutrophils, and macrophages ; INDUCES SMOOTH MUSCLE RELAXATION AND SUBSEQUENT VASODILATION ; INHIBITS PLATELET ACTIVATION and promotes angiogenesis and healthy arterioles
Nitric oxide
45
CONTROLS ACTIVATION OF THE TISSUE FACTOR PATHWAY ; aka EXTRINSIC COAGULATION PATHWAY
Tissue factor pathway inhibitor
46
A known INHIBITOR OF THROMBIN FORMATION and a factor in coagulation pathway
Thrombomodulin
47
Vascular intima has procoagulant property because it is capable of secreting ________________.
von Willebrand factor
48
Enumerate the procoagulant property of the vascular intima
Vasoconstriction Collagen binding and platelet activation Secretion of von Willebrand factor Acts as the necessary bridge that binds platelets to exposed subendothelial collagen Exposes tissue factor and activate coagulation system
49
Refers to the ABILITY of the vascular intima or ECs TO REMOVE/DISSOLVE CLOT
Fibrinolytic property
50
Fibrinolytic property of vascular intima
Tissue plasminogen activator (TPA)
51
This ACTIVATES FIBRINOLYSIS by converting PLASMINOGEN TO PLASMIN which gradually digests fibrin and restores blood flow
Tissue plasminogen activator (TPA)

Hematology 2 (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions