Blood transfusions Flashcards
1
Q
Haemolytic disease of the new born (HDN)
How does it occur?
Which class of abs can cross placenta?
A
A person may from RBC abs through blood transfusion, or if fetal cells enter maternal circ during preg/delivery
Maternal ab high > destroy fetal RBCs > fetal anaemia + jaundice
only IgG can cross placenta
Ab most often responsible is anti-D > so give RhD -ve blood to RhD negative woman of child bearing age
Other abs - anti-c/K, IgG ABO
2
Q
When should you give a mother Anti-D Ig? (3)
A
High risk of feto-maternal haemorrhage
Routine antenal prophylaxis
during pregnancy if sensitizing event occur e.g. misccarage, amniocentesis
at delivery if baby is RhD +ve
3
Q
A
